24,220 research outputs found

    Observations of Large Scale Sidereal Anisotropy in 1 and 11 TeV cosmic rays from the MINOS experiment

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    The MINOS Near and Far Detectors are two large, functionally-identical, steel-scintillating sampling calorimeters located at depths of 220 mwe and 2100 mwe respectively. The detectors observe the muon component of hadronic showers produced from cosmic ray interactions with nuclei in the earth's atmosphere. From the arrival direction of these muons, the anisotropy in arrival direction of the cosmic ray primaries can be determined. The MINOS Near and Far Detector have observed anisotropy on the order of 0.1% at 1 and 11 TeV respectively. The amplitude and phase of the first harmonic at 1 TeV are 8.2±\pm1.7(stat.)×104\times 10^{-4} and (8.9±\pm12.1(stat.))^{\circ}, and at 11 TeV are 3.8±\pm0.5(stat.)×104\times 10^{-4} and (27.2±\pm7.2(stat.))^{\circ}.Comment: 32nd International Cosmic Ray Conference, August 201

    Altered brainstem responses to modafinil in schizophrenia: implications for adjunctive treatment of cognition.

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    Candidate pro-cognitive drugs for schizophrenia targeting several neurochemical systems have consistently failed to demonstrate robust efficacy. It remains untested whether concurrent antipsychotic medications exert pharmacodynamic interactions that mitigate pro-cognitive action in patients. We used functional MRI (fMRI) in a randomized, double-blind, placebo-controlled within-subject crossover test of single-dose modafinil effects in 27 medicated schizophrenia patients, interrogating brainstem regions where catecholamine systems arise to innervate the cortex, to link cellular and systems-level models of cognitive control. Modafinil effects were evaluated both within this patient group and compared to a healthy subject group. Modafinil modulated activity in the locus coeruleus (LC) and ventral tegmental area (VTA) in the patient group. However, compared to the healthy comparison group, these effects were altered as a function of task demands: the control-independent drug effect on deactivation was relatively attenuated (shallower) in the LC and exaggerated (deeper) in the VTA; in contrast, again compared to the comparison group, the control-related drug effects on positive activation were attenuated in LC, VTA and the cortical cognitive control network. These altered effects in the LC and VTA were significantly and specifically associated with the degree of antagonism of alpha-2 adrenergic and dopamine-2 receptors, respectively, by concurrently prescribed antipsychotics. These sources of evidence suggest interacting effects on catecholamine neurons of chronic antipsychotic treatment, which respectively increase and decrease sustained neuronal activity in LC and VTA. This is the first direct evidence in a clinical population to suggest that antipsychotic medications alter catecholamine neuronal activity to mitigate pro-cognitive drug action on cortical circuits

    Coarsening Dynamics of an Antiferromagnetic XY model on the Kagome Lattice: Breakdown of the Critical Dynamic Scaling

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    We find a breakdown of the critical dynamic scaling in the coarsening dynamics of an antiferromagnetic {\em XY} model on the kagome lattice when the system is quenched from disordered states into the Kosterlitz-Thouless ({\em KT}) phases at low temperatures. There exist multiple growing length scales: the length scales of the average separation between fractional vortices are found to be {\em not} proportional to the length scales of the quasi-ordered domains. They are instead related through a nontrivial power-law relation. The length scale of the quasi-ordered domains (as determined from optimal collapse of the correlation functions for the order parameter exp[3iθ(r)]\exp[3 i \theta (r)]) does not follow a simple power law growth but exhibits an anomalous growth with time-dependent effective growth exponent. The breakdown of the critical dynamic scaling is accompanied by unusual relaxation dynamics in the decay of fractional (3θ3\theta) vortices, where the decay of the vortex numbers is characterized by an exponential function of logarithmic powers in time.Comment: 13 pages, 26 figure

    Field efficacy of new compounds to replace copper for scab control in organic apple production

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    Efficacy of compounds was investigated in field experiments in Denmark and the Netherlands according to EPPO guidelines. Some Yucca extracts and potassium bicarbonate had an efficacy similar to sulphur on leaves. Addition of sulphur to Yucca 1 and to potassium bicarbonate increased the level of efficacy to that of copper. This confirms results from earlier years. Although a dose increase resulted in better efficacy, this was more prominent for Yucca1 than for potassium bicarbonate

    Searching for galaxy clusters in the VST-KiDS Survey

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    We present the methods and first results of the search for galaxy clusters in the Kilo Degree Survey (KiDS). The adopted algorithm and the criterium for selecting the member galaxies are illustrated. Here we report the preliminary results obtained over a small area (7 sq. degrees), and the comparison of our cluster candidates with those found in the RedMapper and SZ Planck catalogues; the analysis to a larger area (148 sq. degrees) is currently in progress. By the KiDS cluster search, we expect to increase the completeness of the clusters catalogue to z = 0.6-0.7 compared to RedMapper.Comment: 5 pages, 4 figures, to be published in the Proceedings of the Conference "The Universe of Digital Sky Surveys", Naples, November 25-28 201
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