Galaxy Morphology from NICMOS Parallel Imaging

We present high resolution NICMOS images of random fields obtained in parallel to other HST observations. We present galaxy number counts reaching H=24. The H-band galaxy counts show good agreement with the deepest I- and K-band counts obtained from ground-based data. We present the distribution of galaxies with morphological type to H<23. We find relatively fewer irregular galaxies compared to an I-band sample from the Hubble Deep Field, which we attribute to their blue color, rather than to morphological K-corrections. We conclude that the irregulars are intrinsically faint blue galaxies at z<1.Comment: 13 pages, including 4 figures. Accepted for publication in ApJ Letter

Constraining the unexplored period between reionization and the dark ages with observations of the global 21 cm signal

Observations of the frequency dependence of the global brightness temperature of the redshifted 21 cm line of neutral hydrogen may be possible with single dipole experiments. In this paper, we develop a Fisher matrix formalism for calculating the sensitivity of such instruments to the 21 cm signal from reionization and the dark ages. We show that rapid reionization histories with duration delta z< 2 can be constrained, provided that local foregrounds can be well modelled by low order polynomials. It is then shown that observations in the range nu = 50 - 100 MHz can feasibly constrain the Lyman alpha and X-ray emissivity of the first stars forming at z = 15 - 25, provided that systematic temperature residuals can be controlled to less than 1 mK. Finally, we demonstrate the difficulty of detecting the 21 cm signal from the dark ages before star formation.Comment: 11 pages, 14 figures, submitted to PR

Evolution of the 21 cm signal throughout cosmic history

The potential use of the redshifted 21 cm line from neutral hydrogen for probing the epoch of reionization is motivating the construction of several low-frequency interferometers. There is also much interest in the possibility of constraining the initial conditions from inflation and the nature of the dark matter and dark energy by probing the power-spectrum of density perturbations in three dimensions and on smaller scales than probed by the microwave background anisotropies. Theoretical understanding of the 21 cm signal has been fragmented into different regimes of physical interest. In this paper, we make the first attempt to describe the full redshift evolution of the 21 cm signal between 0<z<300. We include contributions to the 21 cm signal from fluctuations in the gas density, temperature and neutral fraction, as well as the Lyman alpha flux, and allow for a post-reionization signal from damped Ly alpha systems. Our comprehensive analysis provides a useful foundation for optimizing the design of future arrays whose goal is to separate the particle physics from the astrophysics, either by probing the peculiar velocity distortion of the 21 cm power spectrum, or by extending the 21 cm horizon to z > 25 before the first galaxies had formed, or to z < 6 when the residual pockets of hydrogen trace large scale structure.Comment: 15 pages, 11 figures, submitted to PR

Counts and Sizes of Galaxies in the Hubble Deep Field - South: Implications for the Next Generation Space Telescope

Science objectives for the Next Generation Space Telescope (NGST) include a large component of galaxy surveys, both imaging and spectroscopy. The Hubble Deep Field datasets include the deepest observations ever made in the ultraviolet, optical and near infrared, reaching depths comparable to that expected for NGST spectroscopy. We present the source counts, galaxy sizes and isophotal filling factors of the HDF-South images. The observed integrated galaxy counts reach >500 galaxies per square arcminute at AB<30. We extend these counts to faint levels in the infrared using models. The trend previously seen that fainter galaxies are smaller, continues to AB=29 in the high resolution HDF-S STIS image, where galaxies have a typical half-light radius of 0.1 arcseconds. Extensive Monte Carlo simulations show that the small measured sizes are not due to selection effects until >29mag. Using the HDF-S NICMOS image, we show that galaxies are smaller in the near infrared than they are in the optical. We analyze the isophotal filling factor of the HDF-S STIS image, and show that this image is mostly empty sky even at the limits of galaxy detection, a conclusion we expect to hold true for NGST spectroscopy. At the surface brightness limits expected for NGST imaging, however, about a quarter of the sky is occupied by the outer isophotes of AB<30 galaxies. We discuss the implications of these data on several design concepts of the NGST near-infrared spectrograph. We compare the effects of resolution and the confusion limit of various designs, as well as the multiplexing advantages of either multi-object or full-field spectroscopy. We argue that the optimal choice for NGST spectroscopy of high redshift galaxies is a multi-object spectrograph (MOS) with target selection by a micro electro mechanical system (MEMS) device.Comment: 27 pages including 10 figures, accepted for publication in the Astronomical Journal, June 2000, abridged abstrac

Generic local distinguishability and completely entangled subspaces

A subspace of a multipartite Hilbert space is completely entangled if it contains no product states. Such subspaces can be large with a known maximum size, S, approaching the full dimension of the system, D. We show that almost all subspaces with dimension less than or equal to S are completely entangled, and then use this fact to prove that n random pure quantum states are unambiguously locally distinguishable if and only if n does not exceed D-S. This condition holds for almost all sets of states of all multipartite systems, and reveals something surprising. The criterion is identical for separable and for nonseparable states: entanglement makes no difference.Comment: 12 page

Global 21cm signal experiments: a designer's guide

[Abridged] The spatially averaged global spectrum of the redshifted 21cm line has generated much experimental interest, for it is potentially a direct probe of the Epoch of Reionization and the Dark Ages. Since the cosmological signal here has a purely spectral signature, most proposed experiments have little angular sensitivity. This is worrisome because with only spectra, the global 21cm signal can be difficult to distinguish from foregrounds such as Galactic synchrotron radiation, as both are spectrally smooth and the latter is orders of magnitude brighter. We establish a mathematical framework for global signal data analysis in a way that removes foregrounds optimally, complementing spectra with angular information. We explore various experimental design trade-offs, and find that 1) with spectral-only methods, it is impossible to mitigate errors that arise from uncertainties in foreground modeling; 2) foreground contamination can be significantly reduced for experiments with fine angular resolution; 3) most of the statistical significance in a positive detection during the Dark Ages comes from a characteristic high-redshift trough in the 21cm brightness temperature; and 4) Measurement errors decrease more rapidly with integration time for instruments with fine angular resolution. We show that if observations and algorithms are optimized based on these findings, an instrument with a 5 degree beam can achieve highly significant detections (greater than 5-sigma) of even extended (high Delta-z) reionization scenarios after integrating for 500 hrs. This is in contrast to instruments without angular resolution, which cannot detect gradual reionization. Abrupt ionization histories can be detected at the level of 10-100's of sigma. The expected errors are also low during the Dark Ages, with a 25-sigma detection of the expected cosmological signal after only 100 hrs of integration.Comment: 34 pages, 30 figures. Replaced (v2) to match accepted PRD version (minor pedagogical additions to text; methods, results, and conclusions unchanged). Fixed two typos (v3); text, results, conclusions etc. completely unchange

Microlensing and the Surface Brightness Profile of the Afterglow Image of GRB 000301C

The optical afterglow of Gamma-Ray Burst (GRB) 000301C exhibited a significant, short-timescale deviation from the power-law flux decline expected in the standard synchrotron shock model. Garnavich, Loeb & Stanek found that this deviation was well-fit by an ad hoc model in which a thin ring of emission is microlensed by an intervening star. We revisit the microlensing interpretation of this variability, first by testing whether microlensing of afterglow images with realistic surface brightness profiles (SBPs) can fit the data, and second by directly inverting the observed light curve to obtain a non-parametric measurement of the SBP. We find that microlensing of realistic SBPs can reproduce the observed deviation, provided that the optical emission arises from frequencies above the cooling break. Conversely, if the variability is indeed caused by microlensing, the SBP must be significantly limb-brightened. Specifically, greater than 60% of the flux must originate from the outer 25% of the area of the afterglow image. The latter requirement is satisfied by the best fit theoretical SBP. The underlying optical/infrared afterglow lightcurve is consistent with a model in which a jet is propagating into a uniform medium with the cooling break frequency below the optical band.Comment: 14 pages, including 3 figures and 1 Table, very minor changes. Accepted to ApJ main journal. To appear in the November 1, 2001 issue (v561

CELLO: A fast algorithm for Covariance Estimation

We present CELLO (Covariance Estimation and Learning through Likelihood Optimization), an algorithm for predicting the covariances of measurements based on any available informative features. This algorithm is intended to improve the accuracy and reliability of on-line state estimation by providing a principled way to extend the conventional fixed-covariance Gaussian measurement model. We show that in experiments, CELLO learns to predict measurement covariances that agree with empirical covariances obtained by manually annotating sensor regimes. We also show that using the learned covariances during filtering provides substantial quantitative improvement to the overall state estimate. © 2013 IEEE.United States. National Aeronautics and Space AdministrationSiemens Corporate ResearchUnited States. Office of Naval Research. Multidisciplinary University Research InitiativeMicro Autonomous Consortium Systems and Technolog

Adenovirus-Mediated Gene Transfer of Viral Interleukin-10 Inhibits the Immune Response to Both Alloantigen and Adenoviral Antigen

Overview summary Adenoviral vectors are efficient for in vivo delivery of genes to a wide variety of tissue types, whereas the duration of expression is limited by the potent adenovirus-specific immune response directed to the infected cell. In this study, we demonstrate that adenovirus-mediated gene transfer and expression of viral interleukin-10 (vIL-10) not only prolongs murine cardiac allograft survival, but also inhibits the immune response toward adenoviral antigens, and thereby improves the persistence of the vector and extends transgene expression. These findings could be used to design a new generation of adenoviral vector that expresses both an immunosuppressive cytokine gene and another gene of interest. This strategy should have general application in many gene therapy settings other than transplantation. Nonetheless, although the efficacy of adenoviral vectors can be improved by incorporating immunosuppressive genes into the vector, there are also nonimmune mechanisms serving to limit vector gene expression.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/63260/1/hum.1997.8.11-1365.pd

Detecting Population III stars through observations of near-IR cosmic infrared background anisotropies

Following the successful mapping of the last scattering surface by WMAP and balloon experiments, the epoch of the first stars, when Population III stars formed, is emerging as the next cosmological frontier. It is not clear what these stars' properties were, when they formed or how long their era lasted before leading to the stars and galaxies we see today. We show that these questions can be answered with the current and future measurements of the near-IR cosmic infrared background (CIB). Theoretical arguments suggest that Population III stars were very massive and short-lived stars that formed at $z\sim 10-20$ at rare peaks of the density field in the cold-dark-matter Universe. Because Population III stars probably formed individually in small mini-halos, they are not directly accessible to current telescopic studies. We show that these stars left a strong and measurable signature via their contribution to the CIB anisotropies for a wide range of their formation scenarios. The excess in the recently measured near-IR CIB anisotropies over that from normal galaxies can be explained by contribution from early Population III stars. These results imply that Population III were indeed very massive stars and their epoch started at $z\sim 20$ and lasted past z\lsim 13. We show the importance of accurately measuring the CIB anisotropies produced by Population III with future space-based missions.Comment: Ap.J., in press. (Replaced with accepted version