3 research outputs found
TCAg1 supplementary information from A reversible fluorescent probe for monitoring Ag(I) ions
Supplementary figure
Multifunctional Hybrid Nanocarrier: Magnetic CNTs Ensheathed with Mesoporous Silica for Drug Delivery and Imaging System
Here we communicate the development of a novel multifunctional hybrid nanomaterial, magnetic carbon nanotubes (CNTs) ensheathed with mesoporous silica, for the simultaneous applications of drug delivery and imaging. Magnetic nanoparticles (MNPs) were first decorated onto the multiwalled CNTs, which was then layered with mesoporous silica (<i>m</i>SiO<sub>2</sub>) to facilitate the loading of bioactive molecules to a large quantity while exerting magnetic properties. The hybrid nanomaterial showed a high mesoporosity due to the surface-layered <i>m</i>SiO<sub>2</sub>, and excellent magnetic properties, including magnetic resonance imaging in vitro and in vivo. The mesoporous and magnetic hybrid nanocarriers showed high loading capacity for therapeutic molecules including drug gentamicin and protein cytochrome C. In particular, genetic molecule siRNA was effectively loaded and then released over a period of days to a week. Furthermore, the hybrid nanocarriers exhibited a high cell uptake rate through magnetism, while eliciting favorable biological efficacy within the cells. This novel hybrid multifunctional nanocarrier may be potentially applicable as drug delivery and imaging systems
Organosilica Nanoparticles with an Intrinsic Secondary Amine: An Efficient and Reusable Adsorbent for Dyes
Nanomaterials are
promising tools in water remediation because of their large surface
area and unique properties compared to bulky materials. We synthesized
an organosilica nanoparticle (OSNP) and tuned its composition for
anionic dye removal. The adsorption mechanisms are electrostatic attraction
and hydrogen bonding between the amine on OSNP and the dye, and the
surface charge of the OSNP can be tuned to adsorb either anionic or
cationic dyes. Using phenol red as a model dye, we studied the effect
of the amine group, pH, ionic strength, time, dye concentration, and
nanomaterial mass on the adsorption. The theoretical maximum adsorption
capacity was calculated to be 175.44 mg/g (0.47 mmol/g), which is
higher than 67 out of 77 reported adsorbents. The experimental maximum
adsorption capacity is around 201 mg/g (0.53 mmol/g). Furthermore,
the nanoparticles are highly reusable and show stable dye removal
and recovery efficiency over at least 10 cycles. In summary, the novel
adsorbent system derived from the intrinsic amine group within the
frame of OSNP are reusable and tunable for anionic or cationic dyes
with high adsorption capacity and fast adsorption. These materials
may also have utility in drug delivery or as a carrier for imaging
agents