Endotheliopathy is associated with higher levels of cell-free DNA following major trauma: A prospective observational study - Fig 2

<p><b>Association between (a) syndecan-1 and (b) thrombomodulin and cell-free DNA (cfDNA) according to time points.</b><i>P</i>-values are indicated according to Spearman’s rank correlation coefficient. For both concentrations of (a) syndecan-1 and (b) thrombomodulin, there is a significant correlation with concentration of cfDNA at both time points.</p

Endotheliopathy is associated with higher levels of cell-free DNA following major trauma: A prospective observational study - Fig 2

<p><b>Association between (a) syndecan-1 and (b) thrombomodulin and cell-free DNA (cfDNA) according to time points.</b><i>P</i>-values are indicated according to Spearman’s rank correlation coefficient. For both concentrations of (a) syndecan-1 and (b) thrombomodulin, there is a significant correlation with concentration of cfDNA at both time points.</p

Patient characteristics according to requirement for transfusion.

<p>Patient characteristics according to requirement for transfusion.</p

Biomarker concentrations at both time points compared between patients that received a blood transfusion and those who did not.

<p>Biomarker concentrations at both time points compared between patients that received a blood transfusion and those who did not.</p

Patient characteristics according to patient cohort.

<p>Patient characteristics according to patient cohort.</p

Biomarker concentrations at both time points compared between patients that had surgery between time points and those who did not.

<p>Biomarker concentrations at both time points compared between patients that had surgery between time points and those who did not.</p

Correlations between biomarker concentrations at both pre-hospital (<1h) and in-hospital (1-16h) time points and admission INR and PTT ratios.

<p>Correlations between biomarker concentrations at both pre-hospital (<1h) and in-hospital (1-16h) time points and admission INR and PTT ratios.</p

Correlations between biomarker concentrations at both pre-hospital (<1h) and in-hospital (1-16h) time points and length of stay outcomes.

<p>Correlations between biomarker concentrations at both pre-hospital (<1h) and in-hospital (1-16h) time points and length of stay outcomes.</p

Flow diagram of study patients and samples available for analysis.

<p>Flow diagram of study patients and samples available for analysis.</p