Reconsidering Universal Bibliographic Control in Light of the Semantic Web

The goal of universal bibliographic control (UBC) as a world-wide system for the control and exchange of bibliographic information acknowledges the resource discovery metadata requirements of modern, global scale users of information. The first decade of this millennium has seen a significant change in thinking about the functions of UBC and how they can best be realized

Versioning Vocabularies in a Linked Data World

Submitted for and presented to the IFLA 2014 satellite meeting on Linked Open Data in Paris, France, August, 2014.Policies regarding change management in open or public vocabularies used in the context of Linked Open Data have lagged behind those driving other web-based communities of practice. A fresh emphasis on vocabulary management and maintenance has begun to emerge, as the reliance on potentially volatile vocabularies, and the implications of their ongoing growth and change, has begun to permeate the conversation. Particularly in libraries, where management of commonly used vocabularies has long been a community-wide activity, management of vocabularies has been seen as the realm of larger institutions and organizations. This centralized control has been workable (if slow to evolve to incorporate new needs) so long as data distribution has also been centralized, but this pattern of distribution has become more questionable as a transition to the more open world of linked data begins to demonstrate the inflexibility of traditional practices. As more attention shifts to new vocabulary standards and usages outside libraries, researchers and innovative organizations have sought to take advantage of this boom in interest, but unlike librarians, they have little experience in implementation over time. Merging the technology of the Semantic Web with the information management experience of libraries seems a reasonable strategy, but better understanding by all of where practices must change is critical

Orchestrating Metadata Enhancement Services: Introducing Lenny

Harvested metadata often suffers from uneven quality to the point that utility is compromised. Although some aggregators have developed methods for evaluating and repairing specific metadata problems, it has been unclear how these methods might be scaled into services that can be used within an automated production environment. The National Science Digital Library (NSDL), as part of its work with INFOMINE, has developed a model of ser-vice interaction that enables loosely-coupled third party services to provide metadata enhancements to a central repository, with interactions orchestrated by a centralized software application

A Metadata Registry from Vocabularies Up: the NSDL Registry Project

The NSDL Metadata Registry is designed to provide humans and machines with the means to discover, create, access and manage metadata schemes, schemas, application profiles, crosswalks and concept mappings. This paper describes the general goals and architecture of the NSDL Metadata Registry as well as issues encountered during the first year of the project's implementation.This material is based upon work supported by the National Science Foundation under Grant No. DUE-0532828

Geogenomic segregation and temporal trends of human pathogenic Escherichia coli o157:H7, Washington, USA, 2005-2014

The often-noted and persistent increased incidence of Escherichia coli O157:H7 infections in rural areas is not well understood. We used a cohort of E. coli O157:H7 cases reported in Washington, USA, during 2005–2014, along with phylogenomic characterization of the infecting isolates, to identify geographic segregation of and temporal trends in specific phylogenetic lineages of E. coli O157:H7. Kernel estimation and generalized additive models demonstrated that pathogen lineages were spatially segregated during the period of analysis and identified a focus of segregation spanning multiple, predominantly rural, counties for each of the main clinical lineages, Ib, IIa, and IIb. These results suggest the existence of local reservoirs from which humans are infected. We also noted a secular increase in the proportion of lineage IIa and IIb isolates. Spatial segregation by phylogenetic lineage offers the potential to identify local reservoirs and intervene to prevent continued transmission

Core Services in the Architecture of the National Digital Library for Science Education (NSDL)

We describe the core components of the architecture for the (NSDL) National Science, Mathematics, Engineering, and Technology Education Digital Library. Over time the NSDL will include heterogeneous users, content, and services. To accommodate this, a design for a technical and organization infrastructure has been formulated based on the notion of a spectrum of interoperability. This paper describes the first phase of the interoperability infrastructure including the metadata repository, search and discovery services, rights management services, and user interface portal facilities

Best practices to maximize the use and reuse of quantitative and systems pharmacology models: recommendations from the United Kingdom quantitative and systems pharmacology network

The lack of standardization in the way that quantitative and systems pharmacology (QSP) models are developed, tested, and documented hinders their reproducibility, reusability, and expansion or reduction to alternative contexts. This in turn undermines the potential impact of QSP in academic, industrial, and regulatory frameworks. This article presents a minimum set of recommendations from the UK Quantitative and Systems Pharmacology Network (UK QSP Network) to guide QSP practitioners seeking to maximize their impact, and stakeholders considering the use of QSP models in their environment