2,676 research outputs found

    Experimentally Observed Features of the Turbulent Near-Wake of a Model Ship

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    http://deepblue.lib.umich.edu/bitstream/2027.42/116057/1/39015075172091.pd

    Experimentally Observed Features of the Turbulent Near-Wake of a Model Ship

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    https://deepblue.lib.umich.edu/bitstream/2027.42/154136/1/39015075172091.pd

    Understanding tsunami warning systems

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    The eastern Australian coastline faces some 8000km of active tectonic plate boundary that is capable of generating a tsunami thatcould reach Australia in two to four hours. This makes it imperative that coastal communities understand and can respond effectively to the Australian Tsunami Warning System. Activation of this warning system could result in warning times ranging from 90 minutes to three hours. Warning times of these durations could leave insufficient time for people to implement their emergency plan (e.g., to prepare their property, plan an evacuation etc.) on receipt of a warning. This project is researching key aspects of community response capability

    Tidal Streams as Probes of the Galactic Potential

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    We explore the use of tidal streams from Galactic satellites to recover the potential of the Milky Way. Our study is motivated both by the discovery of the first lengthy stellar stream in the halo (\cite{it98}) and by the prospect of measuring proper motions of stars brighter than 20th magnitude in such a stream with an accuracy of ∼4μas/\sim 4\mu as/yr, as will be possible with the Space Interferometry Mission (SIM). We assume that the heliocentric radial velocities of these stars can be determined from supporting ground-based spectroscopic surveys, and that the mass and phase-space coordinates of the Galactic satellite with which they are associated will also be known to SIM accuracy. Using results from numerical simulations as trial data sets, we find that, if we assume the correct form for the Galactic potential, we can predict the distances to the stars as a consequence of the narrow distribution of energy expected along the streams. We develop an algorithm to evaluate the accuracy of any adopted potential by requiring that the satellite and stars recombine within a Galactic lifetime when their current phase-space coordinates are integrated backwards. When applied to a four-dimensional grid of triaxial logarithmic potentials, with varying circular velocities, axis ratios and orientation of the major-axis in the disk plane, the algorithm can recover the parameters used for the Milky Way in a simulated data set to within a few percent using only 100 stars in a tidal stream.Comment: Revised version - original algorithm generalised to be applicable to any potential shape. LaTeX, 12 pages including 3 figures. To be published in ApJ Letter

    Molecular Analysis Expands the Spectrum of Phenotypes Associated with GLI3 Mutations

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    A range of phenotypes including Greig cephalopolysyndactyly and Pallister-Hall syndromes (GCPS, PHS) are caused by pathogenic mutation of the GLI3 gene. To characterize the clinical variability of GLI3 mutations, we present a subset of a cohort of 174 probands referred for GLI3 analysis. Eighty-one probands with typical GCPS or PHS were previously reported, and we report the remaining 93 probands here. This includes 19 probands (12 mutations) who fulfilled clinical criteria for GCPS or PHS, 48 probands (16 mutations) with features of GCPS or PHS but who did not meet the clinical criteria (sub-GCPS and sub-PHS), 21 probands (6 mutations) with features of PHS or GCPS and oral-facial-digital syndrome, and 5 probands (1 mutation) with nonsyndromic polydactyly. These data support previously identified genotype-phenotype correlations and demonstrate a more variable degree of severity than previously recognized. The finding of GLI3 mutations in patients with features of oral-facial-digital syndrome supports the observation that GLI3 interacts with cilia. We conclude that the phenotypic spectrum of GLI3 mutations is broader than that encompassed by the clinical diagnostic criteria, but the genotype-phenotype correlation persists. Individuals with features of either GCPS or PHS should be screened for mutations in GLI3 even if they do not fulfill clinical criteria
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