MICRO DYNAMICS OF INCOME, DEBT MANAGEMENT AND FARM FINANCIAL PERFORMANCE

Agricultural Finance,

The development of a cislunar space infrastructure

The primary objective of this Advanced Mission Design Program is to define the general characteristics and phased evolution of a near-Earth space infrastructure. The envisioned foundation includes a permanently manned, self-sustaining base on the lunar surface, a space station at the Libration Point between earth and the moon (L1), and a transportation system that anchors these elements to the Low Earth Orbit (LEO) station. The implementation of this conceptual design was carried out with the idea that the infrastructure is an important step in a larger plan to expand man's capabilities in space science and technology. Such expansion depends on low cost, reliable, and frequent access to space for those who wish to use the multiple benefits of this environment. The presence of a cislunar space infrastructure would greatly facilitate the staging of future planetary missions, as well as the full exploration of the lunar potential for science and industry. The rationale for, and a proposed detailed scenario in support of, the cislunar space infrastructure are discussed

Biofilm-forming capability of highly virulent, multidrug-resistant Candida auris

The emerging multidrug-resistant yeast pathogen Candida auris has attracted considerable attention as a source of healthcare–associated infections. We report that this highly virulent yeast has the capacity to form antifungal resistant biofilms sensitive to the disinfectant chlorhexidine in vitro

Draft Genome Sequence for Pseudomonas aeruginosa Strain PAO579, a Mucoid Derivative of PAO381

Pseudomonas aeruginosa is an opportunistic pathogen that establishes a chronic lung infection in individuals afflicted with cystic fibrosis. Here, we announce the draft genome of P. aeruginosa strain PAO579, an alginate-overproducing derivative of strain PAO381

A note on reducing spurious pressure oscillations in fully conservative discontinuous Galerkin simulations of multicomponent flows

A well-known issue associated with the use of fully conservative schemes in multicomponent-flow simulations is the generation of spurious pressure oscillations at contact interfaces. These oscillations can rapidly lead to solver divergence even in the presence of smooth interfaces that are not fully resolved. In this note, we compare various strategies for reducing such oscillations that do not (a) introduce conservation error, (b) rely on artificial viscosity or limiting, or (c) degrade order of accuracy in smooth regions of the flow. The considered test case is one-dimensional advection of a high-pressure nitrogen/n-dodecane thermal bubble using the thermally perfect gas model. Several results are presented that contradict those corresponding to the more conventional hydrogen/oxygen thermal-bubble case

Photoreceptor Inner Segment Morphology in Best Vitelliform Macular Dystrophy

PURPOSE To characterize outer retina structure in best vitelliform macular dystrophy (BVMD) and to determine the effect of macular lesions on overlying and adjacent photoreceptors. METHODS Five individuals with BVMD were followed prospectively with spectral domain optical coherence tomography and confocal and nonconfocal split-detector adaptive optics scanning light ophthalmoscopy (AOSLO). The AOSLO cone photoreceptor mosaic images were obtained within and around retinal lesions. Cone density was measured inside and outside lesions. In 2 subjects, densities were compared with published measurements acquired ∼2.5 years before. One subject was imaged 3 times over a 5-month period. RESULTS The AOSLO imaging demonstrated that photoreceptor morphology within BVMD retinal lesions was highly variable depending on the disease stage, with photoreceptor structure present even in advanced disease. The AOSLO imaging was repeatable even in severe disease over short-time and long-time intervals. Photoreceptor density was normal in retinal areas immediately adjacent to lesions and stable over ∼2.5 years. Mobile disk-like structures possibly representing subretinal macrophages were also observed. CONCLUSION Combined confocal and nonconfocal split-detector AOSLO imaging reveals substantial variability within clinical lesions in all stages of BVMD. Longitudinal cellular photoreceptor imaging could prove a powerful tool for understanding disease progression and monitoring emerging therapeutic treatment response in inherited degenerations such as BVMD