Determination of thermotolerant coliforms present in coconut water produced and bottled in the Northeast of Brazil

Abstract Coconut water is considered to be a natural isotonic drink and its marketing is gradually increasing. The objective of the present study was to evaluate the microbiological quality of the coconut water produced and bottled in the Northeast of Brazil. Products form ten industries from different states in the Northeast of Brazil were analyzed. The most probable number (MPN) method was used to quantify the coliforms. Samples showing positive for coliforms were seeded on ChromAgar Orient plates and the bacteria identified from isolated colonies using the automated system Vitek 2 (BioMérieux), according to the manufacturer's instructions for the preparation of the inoculum, incubation, reading and interpretation. The samples showed thermotolerant coliform counts between 6.0×102 and 2.6×104 MPN/100 mL. The presence of Klebsiella pneumoniae, Morganella morganii and Providencia alcalifaciens was observed. The implementation of preventive methods and monitoring of the water quality by the industries is required

Therapeutic approaches in inflammatory diseases: a review

Submitted by Ana Maria Fiscina Sampaio ([email protected]) on 2019-11-13T17:33:14Z No. of bitstreams: 1 Freitas, P.R. Abordagens....pdf: 845223 bytes, checksum: f65267eed486845476ba834b0553b894 (MD5)Approved for entry into archive by Ana Maria Fiscina Sampaio ([email protected]) on 2019-11-13T17:46:21Z (GMT) No. of bitstreams: 1 Freitas, P.R. Abordagens....pdf: 845223 bytes, checksum: f65267eed486845476ba834b0553b894 (MD5)Made available in DSpace on 2019-11-13T17:46:21Z (GMT). No. of bitstreams: 1 Freitas, P.R. Abordagens....pdf: 845223 bytes, checksum: f65267eed486845476ba834b0553b894 (MD5) Previous issue date: 2019Universidade Regional do Cariri. Laboratório de Microbiologia e Biologia Molecular. Cariri, CE, Brasil.Universidade Regional do Cariri. Laboratório de Pesquisa de Produtos Naturais. Cariri, CE, Brasil.Centro Universitário Leão Sampaio. Juazeiro do Norte, CE, Brasil.Centro Universitário Leão Sampaio. Juazeiro do Norte, CE, Brasil.Universidade Regional do Cariri. Laboratório de Microbiologia e Biologia Molecular. Cariri, CE, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.O processo inflamatório é resultante de uma resposta do organismo a uma lesão tecidual com o objetivo de restaurar a homeostase. Inicialmente ocorre o recrutamento e a ativação de leucócitos, mas com a remoção do agente agressor, a resposta inflamatória é programada para cessar, o que chamamos de resolução da inflamação. O presente estudo consiste em uma revisão de literatura sobre as abordagens terapêuticas nas doenças inflamatórias. Em que teve como critérios de inclusão: estudos em inglês, português ou espanhol, cujo o tema central fossem relacionados ao processo inflamatório ou ao tratamento farmacológico destes processos, assim fazendo parte do presente estudo 47 produções selecionadas. Os anti-inflamatórios não-esteroidais (AINEs) e glicocorticoides (GC) são os fármacos mais utilizados para tratar as doenças inflamatórias. Em geral, estas drogas são eficazes para conter o processo inflamatório, porém possuem muitos efeitos colaterais que trazem riscos aos pacientes. Deste modo, a busca por novos compostos que promovam a resolução da inflamação e tragam menos efeitos colaterais aos pacientes é um desafio para as pesquisas voltadas para a farmacologia da inflamaçãoThe inflammatory process is the result of an organism's response to a tissue injury to restore homeostasis. Initially there is recruitment and activation of leukocytes, but with the removal of the offending agent, the inflammatory response is programmed to cease, which we call inflammation resolution. The present study consists of a literature review on therapeutic approaches in inflammatory diseases. In which had as inclusion criteria: studies in English, Portuguese or Spanish, whose central theme were related to the inflammatory process or pharmacological treatment of these processes, thus being part of the present study 47 selected productions. Non-steroidal anti-inflammatory drugs (NSAIDs) and glucocorticoids (GC) are the most commonly used drugs to treat inflammatory diseases. In general, these drugs are effective in containing the inflammatory process, but have many side effects that pose risks to patients. Thus, the search for new compounds that promote inflammation resolution and bring less side effects to patients is a challenge for research focused on the pharmacology of inflammation