Meta-Analysis for the Association between the <i>GAD2</i> −243 A>G Polymorphism and Class III Obesity

<p>French groups 1 and 2 refer to the genotype results from two sets of Caucasian class III obese cases and controls studied by Boutin et al<i>.</i> [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0030315#pbio-0030315-b18" target="_blank">18</a>]. US and Canadian groups were from the present study. The meta-analysis for the association between the −243 G allele and class III obesity yielded a summary OR of 1.11 (95% CI 0.90–1.36), obtained in a total sample of 1,252 class III obese cases and 1,800 controls using a Mantel-Haenszel method and a fixed effects model.</p