Coefficients of significant findings (P < 0.05, adjusted R² > 0, sign consistent with literature) for 52 variables in the univariable analysis, divided by policy area¹.

<p>Coefficients of significant findings (P < 0.05, adjusted R² > 0, sign consistent with literature) for 52 variables in the univariable analysis, divided by policy area<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0188762#t002fn001" target="_blank">¹</a>.</p

Summary of 52 independent and 1 dependent variable in 14 policy areas, 1980–2010¹.

<p>Summary of 52 independent and 1 dependent variable in 14 policy areas, 1980–2010<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0188762#t001fn001" target="_blank">¹</a>.</p

Impact of multisectoral health determinants on child mortality 1980–2010: An analysis by country baseline mortality

<div><p>Introduction</p><p>Some health determinants require relatively stronger health system capacity and socioeconomic development than others to impact child mortality. Few quantitative analyses have analyzed how the impact of health determinants varies by mortality level.</p><p>Methods</p><p>149 low- and middle-income countries were stratified into high, moderate, low, and very low baseline levels of child mortality in 1990. Data for 52 health determinants were collected for these countries for 1980–2010. To quantify how changes in health determinants were associated with mortality decline, univariable and multivariable regression models were constructed. An advanced statistical technique that is new for child mortality analyses—MM-estimation with first differences and country clustering—controlled for outliers, fixed effects, and variation across decades.</p><p>Findings</p><p>Some health determinants (immunizations, education) were consistently associated with child mortality reduction across all mortality levels. Others (staff availability, skilled birth attendance, fertility, water and sanitation) were associated with child mortality reduction mainly in low or very low mortality settings. The findings indicate that the impact of some health determinants on child mortality was only apparent with stronger health systems, public infrastructure and levels of socioeconomic development, whereas the impact of other determinants was apparent at all stages of development. Multisectoral progress was essential to mortality reduction at all baseline mortality levels.</p><p>Conclusion</p><p>Policy-makers can use such analyses to direct investments in health and non-health sectors and to set five-year child mortality targets appropriate for their baseline mortality levels and local context.</p></div

Additional file 8: Table S6. of Overlapping cell population expression profiling and regulatory inference in C. elegans

Anatomy terms enriched in FACS-sorted samples. (XLSX 188 kb

Relative risk for receiving a postnatal home visit within 3 days after birth.

<p>Relative risk for receiving a postnatal home visit within 3 days after birth.</p

Distribution of independent variables¹.

1<p>Missing values were <3% for all variables.</p

Newborn care content of postnatal home visits within 3 days after delivery.

1<p>In Malawi, women were asked what was done by an HSA during any home visit; it was assumed that all reported actions applied to visits that occurred within 3 days of delivery for newborns that received multiple visits.</p>2<p>Counseling on breastfeeding included observation, demonstration, or assessment of breastfeeding.</p>3<p>Check the cord, counsel on breastfeeding, check temperature, and weigh baby were collected in both countries. Counseling on danger signs is excluded since it was only collected in Malawi.</p

Country context.

<p><b>Note:</b> Data for proportion of health facility births in Malawi is from 2010; all other data under the columns marked 2011 is from 2011.</p

Proportion of mothers¹ and newborns receiving CHW home visits in the first week after birth.

<p>This figure shows the percent of mothers and newborns that received a home visit from a community health worker within 0–3 days after birth and 4–7 days after birth in each of the 3 countries included in the analysis – Bangladesh, Malawi, and Nepal. ¹In Nepal, separate questions were asked about postnatal care for the mother and newborn. The woman was asked about only the first two post-discharge checks on her health, but was asked about the first three post-discharge checks for her newborn. Thus the percentage of women visited at home within three days after the birth appears lower than the percentage of newborns visited (41.3% versus 49.6%). Therefore, questions on post-discharge care for the baby were used to calculate the dependent variable in Nepal.</p

Community worker characteristics and home visit schedule, content, and incentives.

1<p>Catchment area population size varies in Nepal depending on terrain; 400 population is based on Terai region such as Bardiya.</p