13 research outputs found
Examples of WMH and microbleeds.
<p>Left: T2-weighted FLAIR images from a mutation carrier with prominent posterior WMH, approximately 5 years prior to symptom onset. Right: example of microbleed (arrow) on a gradient echo MRI scan.</p
Mixed effect regression coefficients for total and regional WMH volumes and CSF biomarkers.
<p>Mixed effect regression coefficients for total and regional WMH volumes and CSF biomarkers.</p
Total and regional WMH volume by microbleed status.
<p>Total and regional WMH volumes are expressed in inverse hyperbolic sine transformation units. Individuals with microbleeds had significantly greater total WMH volumes and WMH volumes in temporal, parietal, and occipital lobes.</p
Covariate adjusted total, indirect and direct effects of mutation status. APOE-4 and age were adjusted in all the models.
<p>The 95% confidence intervals of total, direct and indirect effect were estimated from 1000 bootstrapped samples.</p
Demographic, clinical, and biomarker data in microbleed presence and absence.
<p>Demographic, clinical, and biomarker data in microbleed presence and absence.</p
Longitudinal SUVR analysis for mean cortical regions in mutation carriers.
<p>Longitudinal SUVR analysis for mean cortical regions in mutation carriers.</p
Reproducibility of PiB measurements based on the longitudinal non-carriers cohort (LNC).
<p>Reproducibility of PiB measurements based on the longitudinal non-carriers cohort (LNC).</p
Regional SUV for the cross-sectional cohort.
<p>Regional SUV for the cross-sectional cohort.</p
Mean cortical measurement for longitudinal cohort participants with full dynamic PiB.
<p>Mean cortical measurement for longitudinal cohort participants with full dynamic PiB.</p