Supplement – Body size increases with elevation

Supplemental tables and figure associated with the Copeia publication "Effects of elevation on plethodontid salamander body size

Demographic and Baseline Data.

<p>LEGEND.</p><p>#Composite Score = (Accuracy/RT)*100, Level of difficulty increases from 1 to 3.</p><p>SIPS: Staged Information Processing Speed.</p><p>VSCPUT: Visual Sequence Comparison Thruput.</p><p>VSCRTC: Visual Sequence Comparison Median Response Time DATIRTC – Divided Attention Indicator Alone Median Response Time.</p><p>DIFSCPUT: Difference in Sequence Comparison Alone and Dual Thruput, i.e. DATSCPUT - VSCPUT.</p><p>DIFSCRTC: Difference in Sequence Comparison Alone and Dual Median Response Times.</p><p>DIFINDRTC: Difference Between Divided Attention Indicator Alone and combined with Visual Sequence Comparison, i.e. DATDRTC – DATIRTC.</p><p>SPWB: Scales of Psychological Well Being.</p><p>DASS42: Depression Anxiety & Stress Scales (42 items).</p><p>Average Handling Time: the average time taken to complete an activity, including documentation and review work.</p><p>Conversion Rate: conversion of actions to effective outcomes, a measure of how quickly the collections officer is turning over their cases.</p><p>Kept Rate: a measure of the % of payment arrangements that are adhered to in a defined period of time.</p><p>Quality: the overall grading of an IQF (internal quality framework) assessment.</p><p>Outbound: making telephone calls to clients.</p><p>Inbound: attending to written correspondence.</p><p>Level of Contribution (LOC):rating between 1 and 5 where 1 is Unsatisfactory and 5 is Exceptional.</p><p>Note 1. Productivity measures were provided by the work organisation, as opposed to other measures collected by the research team. There was hence more missing data across this set of outcome measures than others.</p

Short term effects of CT on Divided Attention and Language.

<p>Error bars represent SEMs. P-value is for TIME x TRAINING GROUP interaction.</p

Apolipoprotein levels in different <i>APOE ε</i>4 carrier groups.

<p>Statistics details: ANCOVA, Post-hoc: Bon Ferroni Covariates: age, sex.</p>*<p>Compared to non<i>APOE</i> ε4 carrier, p<0.05, **Compared to non<i>APOE</i> ε4 carrier, p<0.0005.</p>§<p>Compared to <i>APOE</i> ε4 heterozygote carrier, p<0.0005.</p>#<p>When heterozygous and homozygous carriers are pooled and compared with non <i>APOE</i> ε4 carriers the ApoH values are statistically significant (n = 156, mean = 158.95±42.78, F = 4.23, p = 0.04). Pooling of data from heterozygous and homozygous carriers makes no difference to the statistical outcomes for any of the other apolipoproteins, though the significant p values all become even slightly lower.</p

Demographic characteristics of nonconverters and converters at Wave 1.

<p>Demographic characteristics of nonconverters and converters at Wave 1.</p

Partial correlations between apolipoproteins and lipid profiles.

*<p>p<0.05, **p<0.01, *** p<0.001(FDR corrected p values) Covariates: age, sex.</p

Summary of correlations between apolipoproteins and cognitive impairment, cognitive decline and MRI changes over 2 years.

<p>+ Significantly indicates relationship in direction of pathology.</p

Logistic regression analyses for the prediction of conversion from CDR 0 at Wave 1 to CDR >0 at Wave 2 from Wave 1 plasma apolipoprotein levels.

<p>Covariates: age, sex, years of education and <i>APOE</i><b>ε</b>4 carrier status. CVD risk index was also included as a covariate in the series of analyses shown on the left side of table.</p>¶<p>CH, cholesterol; TG, triglycerides; HDL, high density lipoprotein; LDL, low density lipoprotein.</p

Participant Wave 1 demographic information and apolipoprotein levels.

<p>Data are presented as mean±SD.</p><p>Covariates in ANCOVA for effects of apolipoproteins: age, sex, years of education, <i>APOE</i><b>ε</b>4 carrier status, hypolipidaemic medications.</p

Association between pulse wave velocity (continuous) and cognitive domains.

*<p>p<0.05 analysis-wise, none was significant after Bonferroni correction (p<0.0125). Covariates: Age, Years of Education, BMI, Pulse Rate, Systolic BP, Cholesterol, Geriatric Depression Scale Score, ApoE genotype, daily alcohol intake, hormone replacement therapy, history of smoking, use of anti-hypertensive medication, history of cerebrovascular accident, myocardial infarction, transient ischaemic accident, angina, diabetes, and sex for whole sample analyses.</p