Chaperones and protein isomerases identified in pooled plasma from <i>T. b. rhodesiense</i>-infected patients with parasitologically confirmed late stage human African trypanosomiasis.

<p>Chaperones and protein isomerases identified in pooled plasma from <i>T. b. rhodesiense</i>-infected patients with parasitologically confirmed late stage human African trypanosomiasis.</p

Proteases and ubiquitin proteins discovered in pooled plasma from <i>T. b. rhodesiense</i>-infected patients with parasitologically confirmed late stage human African trypanosomiasis.

<p>Proteases and ubiquitin proteins discovered in pooled plasma from <i>T. b. rhodesiense</i>-infected patients with parasitologically confirmed late stage human African trypanosomiasis.</p

Variant Surface Glycoproteins (VSGs) discovered in pooled plasma from <i>T. b. rhodesiense</i>-infected patients confirmed to have late-stage human African trypanosomiasis.

<p>Variant Surface Glycoproteins (VSGs) discovered in pooled plasma from <i>T. b. rhodesiense</i>-infected patients confirmed to have late-stage human African trypanosomiasis.</p

List of human plasma proteins with mass spectrometric molar intensities similar to those from the most abundant trypanosome proteins found in plasma from sleeping sickness patients.

*<p>Protein concentrations were retrieved from reference <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0071463#pone.0071463-Hortin1" target="_blank">[19]</a>. Human proteins reported to be depleted by the LC20 IgY14 and Supermix LC10 columns <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0071463#pone.0071463-Patel1" target="_blank">[26]</a> have been omitted from this table.</p

Summary of patient information.

<p>Plasma and CSF were collected from <i>T. b. rhodesiense</i>-infected patients confirmed to have late stage human African trypanosomiasis at Lwala Hospital in central Uganda.</p

ELISA detection of trypanosome antigens in plasma from <i>T. b. rhodesiense</i> -infected patients with late-stage human African trypanosomisis.

<p>All samples were tested in duplicate and the average response is shown. Error bars represent 1 standard deviation.</p