Einleitung. Radio und Identitätspolitiken

Das Radio erlebt in den letzten Jahren ein Comeback in den Kultur- und Geisteswissenschaften. Eine zentrale Fragestellung ist hierbei die identitäts- und kulturpolitische Nutzung von Klängen und Musik im Radio. Diesem Thema widmen sich die Beiträger_innen aus verschiedenen kulturwissenschaftlichen Disziplinen und knüpfen dabei an die aktuellen Forschungen zur sinnlichen Dimension der Alltagswelt an. Sie fragen nach Akteuren und Praktiken, Interessen und Diskursen sowie nach den institutionellen und gesellschaftlichen Kontexten im Zusammenhang mit Rundfunk und klingendem Kulturgut

Einleitung - Radio und Identitätspolitiken : Kulturwissenschaftliche Perspektiven

Das Radio erlebt in den letzten Jahren ein Comeback in den Kultur- und Geisteswissenschaften. Eine zentrale Fragestellung ist hierbei die identitäts- und kulturpolitische Nutzung von Klängen und Musik im Radio. Diesem Thema widmen sich die Beiträger_innen aus verschiedenen kulturwissenschaftlichen Disziplinen und knüpfen dabei an die aktuellen Forschungen zur sinnlichen Dimension der Alltagswelt an. Sie fragen nach Akteuren und Praktiken, Interessen und Diskursen sowie nach den institutionellen und gesellschaftlichen Kontexten im Zusammenhang mit Rundfunk und klingendem Kulturgut

Einfluss von Habitatmanagement auf die Reduktion von Schadlepidopteren im Kohl

Beneficials can prevent or reduce outbreaks of pest species. To strengthen the populations of beneficials, their food sources must be improved in cultivated areas. The effects of habitat management for augmenting beneficial population on parasitism and predation rates of three lepidopteran pest species were investigated on two organic fields in Alten (Switzerland). The aim was to improve pest regulation through wild flower strips along fields and by planting Centaurea cyanus as companion plant within the crop. Strips of Centaurea cyanus and Fagopyrum esculentum increased parasitsm on the lepidopteran pests. C. cyanus planted as companion plant furthermore increased predation on the eggs and parasitism of the larvae of Mamestra brassicae. Several technical and methodological aspects still need to be improved before the approach is ready for practical use

Discovery of Diverse Small Molecule Chemotypes with Cell-Based PKD1 Inhibitory Activity

Protein kinase D (PKD) is a novel family of serine/threonine kinases regulated by diacylglycerol, which is involved in multiple cellular processes and various pathological conditions. The limited number of cell-active, selective inhibitors has historically restricted biochemical and pharmacological studies of PKD. We now markedly expand the PKD1 inhibitory chemotype inventory with eleven additional novel small molecule PKD1 inhibitors derived from our high throughput screening campaigns. The in vitro IC50s for these eleven compounds ranged in potency from 0.4 to 6.1 µM with all of the evaluated compounds being competitive with ATP. Three of the inhibitors (CID 1893668, (1Z)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one; CID 2011756, 5-(3-chlorophenyl)-N-[4-(morpholin-4-ylmethyl)phenyl]furan-2-carboxamide; CID 5389142, (6Z)-6-[4-(3-aminopropylamino)-6-methyl-1H-pyrimidin-2-ylidene]cyclohexa-2,4-dien-1-one) inhibited phorbol ester-induced endogenous PKD1 activation in LNCaP prostate cancer cells in a concentration-dependent manner. The specificity of these compounds for PKD1 inhibitory activity was supported by kinase assay counter screens as well as by bioinformatics searches. Moreover, computational analyses of these novel cell-active PKD1 inhibitors indicated that they were structurally distinct from the previously described cell-active PKD1 inhibitors while computational docking of the new cell-active compounds in a highly conserved ATP-binding cleft suggests opportunities for structural modification. In summary, we have discovered novel PKD1 inhibitors with in vitro and cell-based inhibitory activity, thus successfully expanding the structural diversity of small molecule inhibitors available for this important pharmacological target

Behavioral responses of terrestrial mammals to COVID-19 lockdowns

DATA AND MATERIALS AVAILABILITY : The full dataset used in the final analyses (33) and associated code (34) are available at Dryad. A subset of the spatial coordinate datasets is available at Zenodo (35). Certain datasets of spatial coordinates will be available only through requests made to the authors due to conservation and Indigenous sovereignty concerns (see table S1 for more information on data use restrictions and contact information for data requests). These sensitive data will be made available upon request to qualified researchers for research purposes, provided that the data use will not threaten the study populations, such as by distribution or publication of the coordinates or detailed maps. Some datasets, such as those overseen by government agencies, have additional legal restrictions on data sharing, and researchers may need to formally apply for data access. Collaborations with data holders are generally encouraged, and in cases where data are held by Indigenous groups or institutions from regions that are under-represented in the global science community, collaboration may be required to ensure inclusion.COVID-19 lockdowns in early 2020 reduced human mobility, providing an opportunity to disentangle its effects on animals from those of landscape modifications. Using GPS data, we compared movements and road avoidance of 2300 terrestrial mammals (43 species) during the lockdowns to the same period in 2019. Individual responses were variable with no change in average movements or road avoidance behavior, likely due to variable lockdown conditions. However, under strict lockdowns 10-day 95th percentile displacements increased by 73%, suggesting increased landscape permeability. Animals’ 1-hour 95th percentile displacements declined by 12% and animals were 36% closer to roads in areas of high human footprint, indicating reduced avoidance during lockdowns. Overall, lockdowns rapidly altered some spatial behaviors, highlighting variable but substantial impacts of human mobility on wildlife worldwide.The Radboud Excellence Initiative, the German Federal Ministry of Education and Research, the National Science Foundation, Serbian Ministry of Education, Science and Technological Development, Dutch Research Council NWO program “Advanced Instrumentation for Wildlife Protection”, Fondation Segré, RZSS, IPE, Greensboro Science Center, Houston Zoo, Jacksonville Zoo and Gardens, Nashville Zoo, Naples Zoo, Reid Park Zoo, Miller Park, WWF, ZCOG, Zoo Miami, Zoo Miami Foundation, Beauval Nature, Greenville Zoo, Riverbanks zoo and garden, SAC Zoo, La Passarelle Conservation, Parc Animalier d’Auvergne, Disney Conservation Fund, Fresno Chaffee zoo, Play for nature, North Florida Wildlife Center, Abilene Zoo, a Liber Ero Fellowship, the Fish and Wildlife Compensation Program, Habitat Conservation Trust Foundation, Teck Coal, and the Grand Teton Association. The collection of Norwegian moose data was funded by the Norwegian Environment Agency, the German Ministry of Education and Research via the SPACES II project ORYCS, the Wyoming Game and Fish Department, Wyoming Game and Fish Commission, Bureau of Land Management, Muley Fanatic Foundation (including Southwest, Kemmerer, Upper Green, and Blue Ridge Chapters), Boone and Crockett Club, Wyoming Wildlife and Natural Resources Trust, Knobloch Family Foundation, Wyoming Animal Damage Management Board, Wyoming Governor’s Big Game License Coalition, Bowhunters of Wyoming, Wyoming Outfitters and Guides Association, Pope and Young Club, US Forest Service, US Fish and Wildlife Service, the Rocky Mountain Elk Foundation, Wyoming Wild Sheep Foundation, Wild Sheep Foundation, Wyoming Wildlife/Livestock Disease Research Partnership, the US National Science Foundation [IOS-1656642 and IOS-1656527, the Spanish Ministry of Economy, Industry and Competitiveness, and by a GRUPIN research grant from the Regional Government of Asturias, Sigrid Rausing Trust, Batubay Özkan, Barbara Watkins, NSERC Discovery Grant, the Federal Aid in Wildlife Restoration act under Pittman-Robertson project, the State University of New York, College of Environmental Science and Forestry, the Ministry of Education, Youth and Sport of the Czech Republic, the Ministry of Agriculture of the Czech Republic, Rufford Foundation, an American Society of Mammalogists African Graduate Student Research Fund, the German Science Foundation, the Israeli Science Foundation, the BSF-NSF, the Ministry of Agriculture, Forestry and Food and Slovenian Research Agency (CRP V1-1626), the Aage V. Jensen Naturfond (project: Kronvildt - viden, værdier og værktøjer), the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy, National Centre for Research and Development in Poland, the Slovenian Research Agency, the David Shepherd Wildlife Foundation, Disney Conservation Fund, Whitley Fund for Nature, Acton Family Giving, Zoo Basel, Columbus, Bioparc de Doué-la-Fontaine, Zoo Dresden, Zoo Idaho, Kolmården Zoo, Korkeasaari Zoo, La Passarelle, Zoo New England, Tierpark Berlin, Tulsa Zoo, the Ministry of Environment and Tourism, Government of Mongolia, the Mongolian Academy of Sciences, the Federal Aid in Wildlife Restoration act and the Illinois Department of Natural Resources, the National Science Foundation, Parks Canada, Natural Sciences and Engineering Research Council, Alberta Environment and Parks, Rocky Mountain Elk Foundation, Safari Club International and Alberta Conservation Association, the Consejo Nacional de Ciencias y Tecnología (CONACYT) of Paraguay, the Norwegian Environment Agency and the Swedish Environmental Protection Agency, EU funded Interreg SI-HR 410 Carnivora Dinarica project, Paklenica and Plitvice Lakes National Parks, UK Wolf Conservation Trust, EURONATUR and Bernd Thies Foundation, the Messerli Foundation in Switzerland and WWF Germany, the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Actions, NASA Ecological Forecasting Program, the Ecotone Telemetry company, the French National Research Agency, LANDTHIRST, grant REPOS awarded by the i-Site MUSE thanks to the “Investissements d’avenir” program, the ANR Mov-It project, the USDA Hatch Act Formula Funding, the Fondation Segre and North American and European Zoos listed at http://www.giantanteater.org/, the Utah Division of Wildlife Resources, the Yellowstone Forever and the National Park Service, Missouri Department of Conservation, Federal Aid in Wildlife Restoration Grant, and State University of New York, various donors to the Botswana Predator Conservation Program, data from collared caribou in the Northwest Territories were made available through funds from the Department of Environment and Natural Resources, Government of the Northwest Territories. The European Research Council Horizon2020, the British Ecological Society, the Paul Jones Family Trust, and the Lord Kelvin Adam Smith fund, the Tanzania Wildlife Research Institute and Tanzania National Parks. The Eastern Shoshone and Northern Arapahoe Fish and Game Department and the Wyoming State Veterinary Laboratory, the Alaska Department of Fish and Game, Kodiak Brown Bear Trust, Rocky Mountain Elk Foundation, Koniag Native Corporation, Old Harbor Native Corporation, Afognak Native Corporation, Ouzinkie Native Corporation, Natives of Kodiak Native Corporation and the State University of New York, College of Environmental Science and Forestry, and the Slovenia Hunters Association and Slovenia Forest Service. F.C. was partly supported by the Resident Visiting Researcher Fellowship, IMéRA/Aix-Marseille Université, Marseille. This work was partially funded by the Center of Advanced Systems Understanding (CASUS), which is financed by Germany’s Federal Ministry of Education and Research (BMBF) and by the Saxon Ministry for Science, Culture and Tourism (SMWK) with tax funds on the basis of the budget approved by the Saxon State Parliament. This article is a contribution of the COVID-19 Bio-Logging Initiative, which is funded in part by the Gordon and Betty Moore Foundation (GBMF9881) and the National Geographic Society.https://www.science.org/journal/sciencehj2023Mammal Research InstituteZoology and Entomolog

Model-Based Selection of Cost-Effective Low Impact Development Strategies to Control Water Balance

Urbanization induces an increase of runoff volume and decrease of evapotranspiration and groundwater recharge. Low impact development (LID) strategies aim to mitigate these adverse impacts. Hydrologic simulation is a reasonable option to assess the LID performance with respect to the water balance and is applicable to planning purposes. Current LID design approaches are based on design storm events and focus on the runoff volume and peak, neglecting evapotranspiration and groundwater recharge. This contribution presents a model-based design approach for the selection of cost-effective LID strategies. The method is based on monitored precipitation time series and considers the complete water balance and life-cycle-costs, as well as the demand for land. The efficiency of LID strategies (ELID) is introduced as an evaluation measure which also accounts for emphasizing different goals. The results show that there exist several pareto-optimal LID strategies providing a reasonable basis for decision-making. Additionally, the application of LID treatment trains emerges as an option of high potential

Sensitivity of Model-Based Water Balance to Low Impact Development Parameters

Low impact development (LID) strategies aim to mitigate the adverse impacts of urbanization, like the increase of runoff and the decrease of evapotranspiration. Hydrological simulation is a reasonable option to evaluate the LID performance with respect to the complete water balance. The sensitivity of water balance components to LID parameters is important for the modeling and planning process of LIDs. This contribution presents the results of a global sensitivity analysis of model-based water balance components (runoff volume, evapotranspiration, groundwater recharge/storage change) using the US Environmental Protection Agency Storm Water Management Model to the parameters (e.g., soil thickness, porosity) of a green roof, an infiltration trench, and a bio-retention cell. All results are based on long-term simulations. The water balance and sensitivity analyses are evaluated for the long-term as well as single storm events. The identification of non-influential and most influential LID parameters for the water balance components is the main outcome of this work. Additionally, the influence of the storm event characteristics precipitation depth and antecedent dry period on the sensitivity of water balance components to LID parameters is shown