Obstetric history and mode of delivery in women with severe maternal morbidity caused by cardiovascular disease.

<p>(PP)CM: (peripartum) cardiomyopathy, VALVE: valvular disease, IHD: ischaemic heart disease, ARR: arrhythmias, AD: aortic dissection, MISC: miscelaneous.</p

Types of cardiovascular disease and its mortality.

*<p>more than one subcategory possible. PPCM: peripartum cardiomyopathy; CM: cardiomyopathy; CHD: congenital heart disease; ACS: acute coronary syndrome; SVT: supraventricular tachycardia; VT: ventricular tachycardia; SADS: Sudden Arrhythmic Death Syndrome.</p

Characteristics of women with severe maternal morbidity caused by cardiovascular disease.

*<p>not including pregnancy-induced hypertension or (pre) eclampsia,</p>∧<p>more than one option possible. (PP)CM: (peripartum) cardiomyopathy, VALVE: valvular disease, IHD: ischaemic heart disease, ARR: arrhythmias, AD: aortic dissection, MISC: miscellaneous.</p

Comparison of possible risk factors for developing severe maternal morbidity and mortality caused by cardiovascular disease between cases and the general pregnant population.

<p>n/a = data not available. RR = relative risk (95% confidence interval) <b>significant</b>.</p>*<p>includes hypertension, diabetes, cardiac disease and coagulation disorders. National reference values from.</p>**<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0056494#pone.0056494-Statistics1" target="_blank">[11]</a> Statistics Netherlands (exact study period) and.</p>***<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0056494#pone.0056494-LVRLandelijke1" target="_blank">[12]</a> The Netherlands Perinatal Registry (LVR-2, 2005).</p

Sum Score during pregnancy and post partum ^a.

<p>^a The repeated measures analysis has been performed using linear mixed effects models. Data are presented in mean and 95% Confidence Interval. Abbreviations: pp, post partum, HELLP, Hemolysis Elevated Liver enzymes Low Platelets.</p

Results of EQ-VAS. MFI and SF-36.

<p>Results of EQ-VAS. MFI and SF-36.</p

Visually assessed EEG.

<p>Visually assessed EEG.</p

Course of Alpha Peak Frequency in a patient who developed Severe Preeclampsia ^a,b,c.

<p>^a Data of patient is presented in red dots. ^b Black line and dotted lines are data of Severe Preeclampsia + HELLP, as presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0155299#pone.0155299.g002" target="_blank">Fig 2</a>. ^c Blue line and dotted lines are data of Normotensive women, as presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0155299#pone.0155299.g002" target="_blank">Fig 2</a>. ^d Red line: patient developed Severe Preeclampsia. Abbreviations: Hz, Hertz; pp, post partum; HELLP, Hemolysis Elevated Liver Enzymes Low Platelets.</p

EEG Sum Score ^a.

<p>^a EEG Sum Score is the sum of items 1 to 6, ranging 0–17 points.</p

Alpha Peak Frequency during pregnancy and post partum ^a.

<p>^a The repeated measures analysis has been performed using linear mixed effects models. Data are presented in mean and 95% Confidence Interval. Abbreviations: Hz, Hertz; pp, post partum, HELLP, Hemolysis Elevated Liver enzymes Low Platelets.</p