Interindividual variability in mean EFV plasma concentrations and mean dose/weight.

<p>Variation in the mean dose/weight (left) and EFV mean plasma concentration (right) in all included patients (n = 36).</p

Summary of administration information for efavirenz (Stocrin).

<p>Summary of administration information for efavirenz (Stocrin).</p

Correlation between dose/weight and efavirenz plasma concentration.

<p>Scatterplot visualizing the EFV plasma concentrations from 36 patients with 182 samples and corresponding dose/weight. Linear regression with cluster robust standard errors: P-EFV (mg/L) = 4.34–0.0556*Dose/Weight (mg/kg/day); p = 0.36; r² = 0.0046.</p

Distribution of log_e mean efavirenz plasma concentration/(dose/weight) by geographical origin.

<p>Number of patients 36 (African 30, Asian 4, Latin American 2), number of samples 182. Mean, standard deviation and 95% confidence interval are incorporated.</p

Relation between genetic variants, age at treatment initiation, time from treatment initiation, sex and log_e EFV plasma concentration/(dose/weight).

<p>Relation between genetic variants, age at treatment initiation, time from treatment initiation, sex and log_e EFV plasma concentration/(dose/weight).</p

Genotype and allele frequency distribution.

<p>Genotype and allele frequency distribution.</p