6 research outputs found
Additional file 2: of Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2
- Author
- Adalgeir Arason (238680)
- Alessandra Viel (10416)
- Alfons Meindl (112058)
- Amanda Toland (3405350)
- Ana Osorio (81750)
- Anders Bojesen (447688)
- Andrea Gehrig (395248)
- Andrew Godwin (811543)
- Angel Izquierdo (3147192)
- Anita Bane (3529403)
- Anna Jakubowska (146752)
- Anna Mulligan (3437741)
- Anne Lincoln (759108)
- Anne-Marie Gerdes (395264)
- Antonella Savarese (3560741)
- Antonio Russo (168018)
- Antonis Antoniou (3405323)
- Ava Kwong (52115)
- Barbara Pasini (3560708)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Beth Karlan (233752)
- Bruce Poppe (797)
- Camille Elan (3560735)
- Christian Singer (3405338)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Rappaport-Fuerhauser (3405320)
- Christoph Engel (218744)
- Claudine Isaacs (59927)
- D. Evans (3405284)
- Daniel Barrowdale (395192)
- Darcy Thull (3560747)
- David Goldgar (29053)
- Debra Frost (154160)
- Dieter Niederacher (93623)
- Domenico Palli (23602)
- Dominique Stoppa-Lyonnet (29241)
- Doris Steinemann (214253)
- Dorothea Wand (3560714)
- Douglas Easton (25461)
- Edith Olah (395204)
- Emily Hallberg (553716)
- Eric Hahnen (112053)
- Esther John (413149)
- Eva Machackova (3560729)
- Evgeny Imyanitov (3405275)
- Fergus Couch (89911)
- Florentia Fostira (387775)
- Gabriella Ivady (3560750)
- George Fountzilas (8221)
- Georgia Chenevix-Trench (361)
- Gero Kramer (3560744)
- Gillian Mitchell (15508)
- Giuseppe Giannini (120417)
- Gord Glendon (146666)
- Heli Nevanlinna (83762)
- Ines Zanna (3560711)
- Inge Pedersen (3398390)
- Irene Andrulis (547071)
- Jan Lubinski (59925)
- Janos Papp (3560699)
- Javier Benitez (81758)
- Jeffrey Weitzel (269835)
- Jo Perkins (3560705)
- Johanna Rantala (547040)
- Joseph Vijai (102398)
- Judith BalmaĂąa (3560759)
- Judy Garber (59512)
- Julian Adlard (395223)
- Karin Kast (112042)
- Katherine Nathanson (547041)
- Kathleen Claes (203063)
- Kathryn Ruddy (3560726)
- Kenneth Offit (63812)
- Kristiina Aittomäki (3437822)
- Kristin Zorn (3405305)
- Laura Cortesi (59703)
- Laura Matricardi (3560738)
- Laura Ottini (395244)
- Laura Papi (395245)
- Laura Spugnesi (3560720)
- Laure Barjhoux (395412)
- Lauren Jacobs (484900)
- Leigha Senter (395286)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Liliana Varesco (381200)
- Linda Steele (395272)
- Louise Izatt (69449)
- Mads Thomassen (395200)
- Manuel Teixeira (3405287)
- Marco Montagna (238698)
- Maria Caligo (3560732)
- Marie Navratilova (197817)
- Mark Greene (3405302)
- Mark Robson (70145)
- Mary Daly (3405308)
- Mary Terry (3405278)
- Melissa Southey (81752)
- Miguel Pujana (3560756)
- Monica Barile (146605)
- Muriel Belotti (395413)
- Nadine Tung (238710)
- Natalie Carter (3560702)
- Norbert Arnold (112045)
- Olufunmilayo Olopade (3405344)
- Orland Diez (395209)
- Oskar Johannsson (55569)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Paul James (435612)
- Pedro Perez Segura (436095)
- Pedro Pinto (542484)
- Peter Hulick (433187)
- Petra Vasickova (3560717)
- Phuong Mai (3437750)
- Piera Rizzolo (3560753)
- Priyanka Sharma (77226)
- Radka Platte (238724)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Robert Nussbaum (3405335)
- Ros Eeles (238725)
- Rosa Barkardottir (3520688)
- Saundra Buys (196721)
- Siranoush Manoukian (146603)
- Sook-Yee Yoon (377792)
- Stefania Tommasi (62342)
- Stephen Fox (152886)
- Steve Ellis (395221)
- Sue Healey (41187)
- Sung-Won Kim (6452)
- Susan Domchek (3405314)
- Susan Neuhausen (3405332)
- Susan Ramus (3405266)
- Thomas Hansen (183190)
- Timothy Rebbeck (569599)
- Tom Van Maerken (105035)
- Trinidad Caldes (3147195)
- Uffe Jensen (3437735)
- Ute Hamann (89879)
- Valentina Silvestri (3560723)
- Valeria Pensotti (395247)
- Yuan Ding (617135)
- Publication venue
- Publication date
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List of local ethics committees that granted approval for the access and use of the data in present study. (DOCX 23 kb
Gene expression interactions in breast cancer survival.
- Author
- Abul Islam (716100)
- Adam Lee (395196)
- Alejandro Sánchez-Gracia (42167)
- Alex Miron (716110)
- Alex Murray (395230)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda E. Toland (238696)
- Ana Osorio (81750)
- Anders Bojesen (447688)
- Andrea Gehrig (395248)
- Andreas Berger (547070)
- Andrew K. Godwin (131285)
- Anna Jakubowska (146752)
- Anna Petit (196517)
- Anne-Marie Gerdes (395264)
- Annelie Liljegren (716112)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Ans M. W. van den Ouweland (395407)
- Antoine de Pauw (196753)
- Antoni Berenguer (122672)
- Antonio Gómez (716114)
- Antonis C. Antoniou (146788)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Beth Y. Karlan (184236)
- Carol Chu (154167)
- Caroline Seynaeve (95368)
- Cecilia M. Dorfling (395285)
- Chiara Gorrini (60042)
- Chris Jacobs (395409)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Maugard (91027)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Christopher A. Maxwell (196486)
- Clare Oliver (196637)
- Conxi Lázaro (142579)
- Cora M. Aalfs (154133)
- Daniel Barrowdale (395192)
- Daniel Cuadras (489400)
- Danylko Villano (716118)
- Daphne Geschwantler-Kaulich (716109)
- David E. Goldgar (196718)
- David M. O'Malley (716106)
- David Margileth (716113)
- Dieter Niederacher (93623)
- Dominique Stoppa-Lyonnet (29241)
- Doris Steinemann (214253)
- Douglas F. Easton (89956)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elena S. Ratner (716107)
- Elisabeth J. van Rensburg (716111)
- Emma McCann (395229)
- Enrique Vidal (716115)
- Esther M. John (107266)
- Eva Tornero (403529)
- Evgeny N. Imyanitov (395207)
- Fergus J. Couch (146607)
- Fiona Lalloo (196644)
- Florentia Fostira (387775)
- Francesca Damiola (5331)
- Francesca Mateo (716101)
- Frans B. L. Hogervorst (146390)
- François Cornelis (260403)
- Gabriella Pichert (69450)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulietta Scuvera (547047)
- Gorka Ruiz de Garibay (535799)
- Gustavo C. Rodriguez (395256)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg J. Plendl (716108)
- Heli Nevanlinna (83762)
- Holger Heyn (126177)
- Huw Dorkins (239925)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene Konstantopoulou (387787)
- Irene L. Andrulis (107262)
- Isabel Català (196512)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benítez (5648629)
- Jeffrey N. Weitzel (238722)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Joan Paterson (716103)
- Johanna Rantala (547040)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judy Garber (59512)
- Julie Cunningham (395292)
- Julio Rozas (42168)
- Juul T. Wijnen (154144)
- Kai-Ren Ong (154173)
- Karin Kast (112042)
- Karoline Kuchenbaecker (547036)
- Katarzyna Durda (146758)
- Katarzyna Jaworska-Bieniek (547065)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- Kelly-Anne A. Phillips (716104)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristiina Aittomäki (89889)
- Lars Jønson (395270)
- Laura Ottini (395244)
- Laure Barjhoux (395412)
- Laurent Castera (38087)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Lidia Feliubadaló (5662999)
- Lone Sunde (547072)
- Loris Bernard (181285)
- Mads Thomassen (395200)
- Manel Esteller (74345)
- Manuel R. Teixeira (118886)
- Marco Montagna (238698)
- Margaret Cook (154156)
- Marie Stenmark-Askmalm (395253)
- Marina J. Corines (716117)
- Marinus J. Blok (395217)
- Marion Fassy-Colcombet (716116)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Matti A. Rookus (154108)
- Melanie Léoné (5663005)
- Miguel Angel Pujana (32854)
- Miguel de la Hoya (238670)
- Muy-Kheng Tea (308359)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane Lindor (154074)
- Norbert Arnold (112045)
- Núria Bonifaci (196493)
- Olga M. Sinilnikova (196738)
- Orland Díez (5663002)
- Pablo Librado (716099)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascaline Berthet (395233)
- Penny Soucy (21792)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Rita K. Schmutzler (112064)
- Rob B. van der Luijt (196627)
- Robert L. Nussbaum (263844)
- Rosa B. Barkardottir (238688)
- Sabine Preisler-Adams (395251)
- Sandra Fert Ferrer (196769)
- Sergi Sayols (126193)
- Shan Wang-Gohrke (89910)
- Shani Shimon Paluch (395262)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Stacy R. Nerenstone (716105)
- Steven A. Narod (230773)
- Sue Healey (41187)
- Susan L. Neuhausen (238692)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Teresa Ramón y Cajal (460449)
- Thomas V. Hansen (716102)
- Timothy R. Rebbeck (230766)
- Tom Van Maerken (105035)
- Torben A. Kruse (92928)
- Trinidad Caldés (196674)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yves-Jean Bignon (54433)
- Publication venue
- Publication date
- Field of study
<p>(<b>A</b>) Kaplan–Meier survival curves based on categorization of <i>HMMR</i> (probe NM_012484) and <i>AURKA</i> (NM_003600) expression in tertiles (low, medium or high expression). For simplicity, only the tertiles for “high” <i>AURKA</i> are shown. The tumours with high expression levels for both genes were not those with the poorest prognosis. (<b>B</b>) Kaplan–Meier survival curves based on categorization of <i>HMMR</i> (NM_012484) and <i>TUBG1</i> (NM_016437) expression in tertiles (low, medium or high expression). For simplicity, only the tertiles for “high” <i>HMMR</i> are shown. The cases with high expression levels for both genes were those with the poorest prognosis.</p
Potential GxG associated with breast cancer risk in <i>BRCA1/2</i> mutation carriers.
- Author
- Abul Islam (716100)
- Adam Lee (395196)
- Alejandro Sánchez-Gracia (42167)
- Alex Miron (716110)
- Alex Murray (395230)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda E. Toland (238696)
- Ana Osorio (81750)
- Anders Bojesen (447688)
- Andrea Gehrig (395248)
- Andreas Berger (547070)
- Andrew K. Godwin (131285)
- Anna Jakubowska (146752)
- Anna Petit (196517)
- Anne-Marie Gerdes (395264)
- Annelie Liljegren (716112)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Ans M. W. van den Ouweland (395407)
- Antoine de Pauw (196753)
- Antoni Berenguer (122672)
- Antonio Gómez (716114)
- Antonis C. Antoniou (146788)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Beth Y. Karlan (184236)
- Carol Chu (154167)
- Caroline Seynaeve (95368)
- Cecilia M. Dorfling (395285)
- Chiara Gorrini (60042)
- Chris Jacobs (395409)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Maugard (91027)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Christopher A. Maxwell (196486)
- Clare Oliver (196637)
- Conxi Lázaro (142579)
- Cora M. Aalfs (154133)
- Daniel Barrowdale (395192)
- Daniel Cuadras (489400)
- Danylko Villano (716118)
- Daphne Geschwantler-Kaulich (716109)
- David E. Goldgar (196718)
- David M. O'Malley (716106)
- David Margileth (716113)
- Dieter Niederacher (93623)
- Dominique Stoppa-Lyonnet (29241)
- Doris Steinemann (214253)
- Douglas F. Easton (89956)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elena S. Ratner (716107)
- Elisabeth J. van Rensburg (716111)
- Emma McCann (395229)
- Enrique Vidal (716115)
- Esther M. John (107266)
- Eva Tornero (403529)
- Evgeny N. Imyanitov (395207)
- Fergus J. Couch (146607)
- Fiona Lalloo (196644)
- Florentia Fostira (387775)
- Francesca Damiola (5331)
- Francesca Mateo (716101)
- Frans B. L. Hogervorst (146390)
- François Cornelis (260403)
- Gabriella Pichert (69450)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulietta Scuvera (547047)
- Gorka Ruiz de Garibay (535799)
- Gustavo C. Rodriguez (395256)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg J. Plendl (716108)
- Heli Nevanlinna (83762)
- Holger Heyn (126177)
- Huw Dorkins (239925)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene Konstantopoulou (387787)
- Irene L. Andrulis (107262)
- Isabel Català (196512)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benítez (5648629)
- Jeffrey N. Weitzel (238722)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Joan Paterson (716103)
- Johanna Rantala (547040)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judy Garber (59512)
- Julie Cunningham (395292)
- Julio Rozas (42168)
- Juul T. Wijnen (154144)
- Kai-Ren Ong (154173)
- Karin Kast (112042)
- Karoline Kuchenbaecker (547036)
- Katarzyna Durda (146758)
- Katarzyna Jaworska-Bieniek (547065)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- Kelly-Anne A. Phillips (716104)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristiina Aittomäki (89889)
- Lars Jønson (395270)
- Laura Ottini (395244)
- Laure Barjhoux (395412)
- Laurent Castera (38087)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Lidia Feliubadaló (5662999)
- Lone Sunde (547072)
- Loris Bernard (181285)
- Mads Thomassen (395200)
- Manel Esteller (74345)
- Manuel R. Teixeira (118886)
- Marco Montagna (238698)
- Margaret Cook (154156)
- Marie Stenmark-Askmalm (395253)
- Marina J. Corines (716117)
- Marinus J. Blok (395217)
- Marion Fassy-Colcombet (716116)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Matti A. Rookus (154108)
- Melanie Léoné (5663005)
- Miguel Angel Pujana (32854)
- Miguel de la Hoya (238670)
- Muy-Kheng Tea (308359)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane Lindor (154074)
- Norbert Arnold (112045)
- Núria Bonifaci (196493)
- Olga M. Sinilnikova (196738)
- Orland Díez (5663002)
- Pablo Librado (716099)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascaline Berthet (395233)
- Penny Soucy (21792)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Rita K. Schmutzler (112064)
- Rob B. van der Luijt (196627)
- Robert L. Nussbaum (263844)
- Rosa B. Barkardottir (238688)
- Sabine Preisler-Adams (395251)
- Sandra Fert Ferrer (196769)
- Sergi Sayols (126193)
- Shan Wang-Gohrke (89910)
- Shani Shimon Paluch (395262)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Stacy R. Nerenstone (716105)
- Steven A. Narod (230773)
- Sue Healey (41187)
- Susan L. Neuhausen (238692)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Teresa Ramón y Cajal (460449)
- Thomas V. Hansen (716102)
- Timothy R. Rebbeck (230766)
- Tom Van Maerken (105035)
- Torben A. Kruse (92928)
- Trinidad Caldés (196674)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yves-Jean Bignon (54433)
- Publication venue
- Publication date
- Field of study
<p>*Each estimate is derived from the interaction term of a Cox regression model.</p><p>Potential GxG associated with breast cancer risk in <i>BRCA1/2</i> mutation carriers.</p
The <i>HMMR</i> locus and breast cancer risk in <i>BRCA1</i> mutation carriers.
- Author
- Abul Islam (716100)
- Adam Lee (395196)
- Alejandro Sánchez-Gracia (42167)
- Alex Miron (716110)
- Alex Murray (395230)
- Alfons Meindl (112058)
- Alison M. Dunning (146796)
- Amanda B. Spurdle (47489)
- Amanda E. Toland (238696)
- Ana Osorio (81750)
- Anders Bojesen (447688)
- Andrea Gehrig (395248)
- Andreas Berger (547070)
- Andrew K. Godwin (131285)
- Anna Jakubowska (146752)
- Anna Petit (196517)
- Anne-Marie Gerdes (395264)
- Annelie Liljegren (716112)
- Anneliese Fink-Retter (395258)
- Annemarie H. van der Hout (395213)
- Ans M. W. van den Ouweland (395407)
- Antoine de Pauw (196753)
- Antoni Berenguer (122672)
- Antonio Gómez (716114)
- Antonis C. Antoniou (146788)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Beth Y. Karlan (184236)
- Carol Chu (154167)
- Caroline Seynaeve (95368)
- Cecilia M. Dorfling (395285)
- Chiara Gorrini (60042)
- Chris Jacobs (395409)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Lasset (395236)
- Christine Maugard (91027)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Christopher A. Maxwell (196486)
- Clare Oliver (196637)
- Conxi Lázaro (142579)
- Cora M. Aalfs (154133)
- Daniel Barrowdale (395192)
- Daniel Cuadras (489400)
- Danylko Villano (716118)
- Daphne Geschwantler-Kaulich (716109)
- David E. Goldgar (196718)
- David M. O'Malley (716106)
- David Margileth (716113)
- Dieter Niederacher (93623)
- Dominique Stoppa-Lyonnet (29241)
- Doris Steinemann (214253)
- Douglas F. Easton (89956)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elena S. Ratner (716107)
- Elisabeth J. van Rensburg (716111)
- Emma McCann (395229)
- Enrique Vidal (716115)
- Esther M. John (107266)
- Eva Tornero (403529)
- Evgeny N. Imyanitov (395207)
- Fergus J. Couch (146607)
- Fiona Lalloo (196644)
- Florentia Fostira (387775)
- Francesca Damiola (5331)
- Francesca Mateo (716101)
- Frans B. L. Hogervorst (146390)
- François Cornelis (260403)
- Gabriella Pichert (69450)
- Gad Rennert (196538)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulietta Scuvera (547047)
- Gorka Ruiz de Garibay (535799)
- Gustavo C. Rodriguez (395256)
- Hanne E. J. Meijers-Heijboer (395215)
- Hansjoerg J. Plendl (716108)
- Heli Nevanlinna (83762)
- Holger Heyn (126177)
- Huw Dorkins (239925)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene Konstantopoulou (387787)
- Irene L. Andrulis (107262)
- Isabel Català (196512)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benítez (5648629)
- Jeffrey N. Weitzel (238722)
- Jenny Lester (395276)
- Joan Brunet (75020)
- Joan Paterson (716103)
- Johanna Rantala (547040)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judy Garber (59512)
- Julie Cunningham (395292)
- Julio Rozas (42168)
- Juul T. Wijnen (154144)
- Kai-Ren Ong (154173)
- Karin Kast (112042)
- Karoline Kuchenbaecker (547036)
- Katarzyna Durda (146758)
- Katarzyna Jaworska-Bieniek (547065)
- Katherine L. Nathanson (154077)
- Kathleen Claes (203063)
- Kelly-Anne A. Phillips (716104)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kristiina Aittomäki (89889)
- Lars Jønson (395270)
- Laura Ottini (395244)
- Laure Barjhoux (395412)
- Laurent Castera (38087)
- Lenka Foretova (162255)
- Lesley McGuffog (153865)
- Lidia Feliubadaló (5662999)
- Lone Sunde (547072)
- Loris Bernard (181285)
- Mads Thomassen (395200)
- Manel Esteller (74345)
- Manuel R. Teixeira (118886)
- Marco Montagna (238698)
- Margaret Cook (154156)
- Marie Stenmark-Askmalm (395253)
- Marina J. Corines (716117)
- Marinus J. Blok (395217)
- Marion Fassy-Colcombet (716116)
- Marion Piedmonte (238646)
- Marjolijn J. L. Ligtenberg (395218)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mary B. Daly (196724)
- Mary Beth Terry (2801)
- Matti A. Rookus (154108)
- Melanie Léoné (5663005)
- Miguel Angel Pujana (32854)
- Miguel de la Hoya (238670)
- Muy-Kheng Tea (308359)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane Lindor (154074)
- Norbert Arnold (112045)
- Núria Bonifaci (196493)
- Olga M. Sinilnikova (196738)
- Orland Díez (5663002)
- Pablo Librado (716099)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Pascaline Berthet (395233)
- Penny Soucy (21792)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Ramunas Janavicius (71877)
- Raymonda Varon-Mateeva (196729)
- Rita K. Schmutzler (112064)
- Rob B. van der Luijt (196627)
- Robert L. Nussbaum (263844)
- Rosa B. Barkardottir (238688)
- Sabine Preisler-Adams (395251)
- Sandra Fert Ferrer (196769)
- Sergi Sayols (126193)
- Shan Wang-Gohrke (89910)
- Shani Shimon Paluch (395262)
- Simona Agata (395280)
- Siranoush Manoukian (146603)
- Stacy R. Nerenstone (716105)
- Steven A. Narod (230773)
- Sue Healey (41187)
- Susan L. Neuhausen (238692)
- Susan M. Domchek (154078)
- Susan Peock (154155)
- Sylvie Mazoyer (196744)
- Teresa Ramón y Cajal (460449)
- Thomas V. Hansen (716102)
- Timothy R. Rebbeck (230766)
- Tom Van Maerken (105035)
- Torben A. Kruse (92928)
- Trinidad Caldés (196674)
- Uffe Birk Jensen (395267)
- Ute Hamann (89879)
- Vernon S. Pankratz (395294)
- Victoria L. Bae-Jump (284536)
- Wendy K. Chung (51418)
- Xianshu Wang (146610)
- Yael Laitman (196595)
- Yves-Jean Bignon (54433)
- Publication venue
- Publication date
- Field of study
<p>(<b>A</b>) Forest plots showing rs299290 HRs and 95% CIs (retrospective likelihood trend estimation) for participating countries (relatively small sample sets are not shown) ordered by sample size. Left and right panels show results for <i>BRCA1</i> and <i>BRCA2</i> mutation carriers, respectively. The sizes of the rectangles are proportional to the corresponding country/study precision. (<b>B</b>) The rs299290-containing region, including the genes, variation and regulatory evidence mentioned in HMECs. Exons are marked by black-filled rectangles and the direction of transcription is marked by arrows in the genomic structure. The chromosome 5 positions (base pairs (bp)) and linkage disequilibrium structure from Caucasian HapMap individuals are also shown.</p
p-values of association (−log10 scale) with breast cancer risk in <i>BRCA2</i> carriers for genotyped and imputed SNPs in the <i>NEIL2</i> gene.
- Author
- A. H. van der Hout (547063)
- Alan Donaldson (239924)
- Alessandra Viel (10416)
- Alex Teulé (395273)
- Alfons Meindl (112058)
- Alice S. Whittemore (218502)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Anders Bojesen (447688)
- Andrea Gehrig (395248)
- Andreas Berger (547070)
- Andrew K. Godwin (131285)
- Andrew Lee (74302)
- Anna Jakubowska (146752)
- Anna Marie Mulligan (146672)
- Anne-Marie Gerdes (395264)
- Anneliese Fink-Retter (395258)
- Antonis C. Antoniou (146788)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Belén Herráez (547043)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Beth Y. Karlan (184236)
- Brita Arver (395252)
- Bruce Poppe (797)
- Carole Brewer (196650)
- Carolien H. M. van Deurzen (395214)
- Catherine M. Phelan (219497)
- Cecilia M. Dorfling (395285)
- Cezary Cybulski (196608)
- Christi J. van Asperen (89901)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Maugard (91027)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Claire Foo (547054)
- Conxi Lázaro (142579)
- Cristina Martinez-Bouzas (436091)
- Csilla I. Szabo (395202)
- Curtis Olswold (73571)
- Daniel Barrowdale (395192)
- Daniela Zaffaroni (547046)
- Daphne Geschwantler Kaulich (547069)
- Debra Frost (154160)
- Diana Eccles (154169)
- Dieter Niederacher (93623)
- Dominique Stoppa-Lyonnet (29241)
- Doris Steinemann (214253)
- Douglas F. Easton (89956)
- Drakoulis Yannoukakos (4758)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elizabeth J. van Rensburg (395205)
- Encarna B. Gómez García (154147)
- Esther M. John (107266)
- Fergus J. Couch (146607)
- Fiona Douglas (154179)
- Fiona Lalloo (196644)
- Flavio Lejbkowicz (196544)
- Floor Backes (547056)
- Francesca Damiola (5331)
- Frederique Mariette (181306)
- Gareth Evans (547048)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulietta Scuvera (547047)
- Gord Glendon (146666)
- Guillermo Pita (81757)
- Gustavo Rodríguez (547057)
- Hanne E. J. Meijers-Heijboer (395215)
- Hans Ehrencrona (196663)
- Hans Jörg Plendl (547055)
- HEBON (154096)
- Heli Nevanlinna (83762)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene Andrulis (547071)
- Irene Konstantopoulou (387787)
- J. L. de Lange (547062)
- J. Margriet Collee (89936)
- Jacek Gronwald (218515)
- Jackie Cook (154176)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jenny Lester (395276)
- Johanna Rantala (547040)
- John Hopper (218871)
- John Kennedy (547053)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judy Garber (59512)
- Julian Adlard (395223)
- Karin Kast (112042)
- Karoline Kuchenbaecker (547036)
- Katarzyna Durda (146758)
- Katarzyna Jaworska-Bieniek (547065)
- Katherine Nathanson (547041)
- Kathleen Claes (203063)
- Kathy Tucker (62074)
- Katie Wakeley (547059)
- KConFab Investigators (41190)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kisa Weeman (547045)
- Kristiina Aittomäki (89889)
- Lars Jønson (395270)
- Laura Ottini (395244)
- Laura Papi (395245)
- Lesley McGuffog (153865)
- Leticia Thais Moreno (547044)
- Liliana Varesco (381200)
- Linda Steele (395272)
- Lisa Walker (238726)
- Liying Zhang (102453)
- Lizet van der Kolk (547061)
- Lone Sunde (547072)
- Louise Izatt (69449)
- Lucia Guidugli (547067)
- Lucy Side (547051)
- Mads Thomassen (395200)
- Manuel R. Teixeira (118886)
- Mar Infante (436090)
- Marc Tischkowitz (395208)
- Marco Montagna (238698)
- Maria Grazia Tibiletti (395246)
- Marion Piedmonte (238646)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mary B. Daly (196724)
- Mary B. Terry (547042)
- Mary Porteous (547050)
- Mary S. Beattie (395206)
- Matti A. Rookus (154108)
- Melissa Southey (81752)
- Mercedes Durán (238719)
- Miguel de la Hoya (238670)
- Mireia Menéndez (547064)
- Muy-Kheng Tea (308359)
- Nicoline Hoogerbrugge (81756)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane Lindor (154074)
- Norbert Arnold (112045)
- Olga M. Sinilnikova (196738)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Oskar Th. Johannsson (547066)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Patrick Morrison (547052)
- Penny Soucy (21792)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Radka Platte (238724)
- Ramunas Janavicius (71877)
- Raquel Andrés Conejero (547039)
- Raymonda Varon-Mateeva (196729)
- Rita Katharina Schmutzler (395199)
- Rob B. van der Luijt (196627)
- Roger L. Milne (89874)
- Rohini Rau-Murthy (102417)
- Ros Eeles (238725)
- Rosario Alonso (547038)
- Rosemarie Davidson (154164)
- Sabine Preisler-Adams (395251)
- Sara Volorio (255289)
- Saundra S. Buys (238707)
- Shan Wang-Gohrke (89910)
- Shani Paluch Shimon (547073)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Siranoush Manoukian (146603)
- Steve Ellis (395221)
- Sue Healey (41187)
- Susan L. Neuhausen (238692)
- Susan M. Domchek (154078)
- Susan Slager (547068)
- SWE-BRCA (154081)
- Sylvie Mazoyer (196744)
- Teresa Ramón y Cajal (460449)
- Tereza Vaclová (547037)
- Theo A. M. van Os (395220)
- Thomas Rutherford (547060)
- Thomas V. O. Hansen (395201)
- Timothy R. Rebbeck (230766)
- Torben A. Kruse (92928)
- Trevor Cole (547049)
- Trinidad Caldés (196674)
- Uffe Birk Jensen (395267)
- Wendy Brewster (547058)
- Yael Laitman (196595)
- Yuan Chun Ding (322601)
- Publication venue
- Publication date
- Field of study
<p>SNP rs1466785 is indicated with a purple arrow and the best causal imputed SNPs, rs804276 and rs804271 are indicated with a red arrow. Colors represent the pariwise r<sup>2</sup>. Plot generated with LocusZoom <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004256#pgen.1004256-Pruim1" target="_blank">[42]</a> (<a href="http://csg.sph.umich.edu/locuszoom/" target="_blank">http://csg.sph.umich.edu/locuszoom/</a>).</p
Associations with breast and ovarian cancer risk for SNPs observed at p-trend<0.05 in stage II of the experiment.
- Author
- A. H. van der Hout (547063)
- Alan Donaldson (239924)
- Alessandra Viel (10416)
- Alex Teulé (395273)
- Alfons Meindl (112058)
- Alice S. Whittemore (218502)
- Amanda Ewart Toland (164514)
- Ana Osorio (81750)
- Anders Bojesen (447688)
- Andrea Gehrig (395248)
- Andreas Berger (547070)
- Andrew K. Godwin (131285)
- Andrew Lee (74302)
- Anna Jakubowska (146752)
- Anna Marie Mulligan (146672)
- Anne-Marie Gerdes (395264)
- Anneliese Fink-Retter (395258)
- Antonis C. Antoniou (146788)
- Banu K. Arun (395211)
- Barbara Wappenschmidt (112030)
- Belén Herráez (547043)
- Bent Ejlertsen (395269)
- Bernard Peissel (181321)
- Bernardo Bonanni (196561)
- Beth Y. Karlan (184236)
- Brita Arver (395252)
- Bruce Poppe (797)
- Carole Brewer (196650)
- Carolien H. M. van Deurzen (395214)
- Catherine M. Phelan (219497)
- Cecilia M. Dorfling (395285)
- Cezary Cybulski (196608)
- Christi J. van Asperen (89901)
- Christian F. Singer (308365)
- Christian Sutter (196732)
- Christine Maugard (91027)
- Christine Rappaport (395259)
- Christine Walsh (219475)
- Christoph Engel (218744)
- Claire Foo (547054)
- Conxi Lázaro (142579)
- Cristina Martinez-Bouzas (436091)
- Csilla I. Szabo (395202)
- Curtis Olswold (73571)
- Daniel Barrowdale (395192)
- Daniela Zaffaroni (547046)
- Daphne Geschwantler Kaulich (547069)
- Debra Frost (154160)
- Diana Eccles (154169)
- Dieter Niederacher (93623)
- Dominique Stoppa-Lyonnet (29241)
- Doris Steinemann (214253)
- Douglas F. Easton (89956)
- Drakoulis Yannoukakos (4758)
- Edith Olah (395204)
- Eitan Friedman (196582)
- Elena Fineberg (395222)
- Elizabeth J. van Rensburg (395205)
- Encarna B. Gómez García (154147)
- Esther M. John (107266)
- Fergus J. Couch (146607)
- Fiona Douglas (154179)
- Fiona Lalloo (196644)
- Flavio Lejbkowicz (196544)
- Floor Backes (547056)
- Francesca Damiola (5331)
- Frederique Mariette (181306)
- Gareth Evans (547048)
- Georg Pfeiler (395261)
- Georgia Chenevix-Trench (361)
- Giulietta Scuvera (547047)
- Gord Glendon (146666)
- Guillermo Pita (81757)
- Gustavo Rodríguez (547057)
- Hanne E. J. Meijers-Heijboer (395215)
- Hans Ehrencrona (196663)
- Hans Jörg Plendl (547055)
- HEBON (154096)
- Heli Nevanlinna (83762)
- Ignacio Blanco (196711)
- Inge Sokilde Pedersen (395265)
- Irene Andrulis (547071)
- Irene Konstantopoulou (387787)
- J. L. de Lange (547062)
- J. Margriet Collee (89936)
- Jacek Gronwald (218515)
- Jackie Cook (154176)
- Jacques Simard (15589)
- Jan Lubinski (59925)
- Javier Benitez (81758)
- Jeffrey N. Weitzel (238722)
- Jenny Lester (395276)
- Johanna Rantala (547040)
- John Hopper (218871)
- John Kennedy (547053)
- Josef Herzog (395277)
- Joseph Vijai (102398)
- Judy Garber (59512)
- Julian Adlard (395223)
- Karin Kast (112042)
- Karoline Kuchenbaecker (547036)
- Katarzyna Durda (146758)
- Katarzyna Jaworska-Bieniek (547065)
- Katherine Nathanson (547041)
- Kathleen Claes (203063)
- Kathy Tucker (62074)
- Katie Wakeley (547059)
- KConFab Investigators (41190)
- Kenneth Offit (63812)
- Kerstin Rhiem (112049)
- Kisa Weeman (547045)
- Kristiina Aittomäki (89889)
- Lars Jønson (395270)
- Laura Ottini (395244)
- Laura Papi (395245)
- Lesley McGuffog (153865)
- Leticia Thais Moreno (547044)
- Liliana Varesco (381200)
- Linda Steele (395272)
- Lisa Walker (238726)
- Liying Zhang (102453)
- Lizet van der Kolk (547061)
- Lone Sunde (547072)
- Louise Izatt (69449)
- Lucia Guidugli (547067)
- Lucy Side (547051)
- Mads Thomassen (395200)
- Manuel R. Teixeira (118886)
- Mar Infante (436090)
- Marc Tischkowitz (395208)
- Marco Montagna (238698)
- Maria Grazia Tibiletti (395246)
- Marion Piedmonte (238646)
- Mark H. Greene (395203)
- Mark Robson (70145)
- Mary B. Daly (196724)
- Mary B. Terry (547042)
- Mary Porteous (547050)
- Mary S. Beattie (395206)
- Matti A. Rookus (154108)
- Melissa Southey (81752)
- Mercedes Durán (238719)
- Miguel de la Hoya (238670)
- Mireia Menéndez (547064)
- Muy-Kheng Tea (308359)
- Nicoline Hoogerbrugge (81756)
- Niklas Loman (26096)
- Nina Ditsch (395249)
- Noah Kauff (395268)
- Noralane Lindor (154074)
- Norbert Arnold (112045)
- Olga M. Sinilnikova (196738)
- Olufunmilayo I. Olopade (151873)
- Orland Diez (395209)
- Oskar Th. Johannsson (547066)
- Paolo Peterlongo (146602)
- Paolo Radice (146601)
- Patrick Morrison (547052)
- Penny Soucy (21792)
- Peter Devilee (13431)
- Phuong L. Mai (238716)
- Radka Platte (238724)
- Ramunas Janavicius (71877)
- Raquel Andrés Conejero (547039)
- Raymonda Varon-Mateeva (196729)
- Rita Katharina Schmutzler (395199)
- Rob B. van der Luijt (196627)
- Roger L. Milne (89874)
- Rohini Rau-Murthy (102417)
- Ros Eeles (238725)
- Rosario Alonso (547038)
- Rosemarie Davidson (154164)
- Sabine Preisler-Adams (395251)
- Sara Volorio (255289)
- Saundra S. Buys (238707)
- Shan Wang-Gohrke (89910)
- Shani Paluch Shimon (547073)
- Shirley Hodgson (154183)
- Silvia Tognazzo (395279)
- Siranoush Manoukian (146603)
- Steve Ellis (395221)
- Sue Healey (41187)
- Susan L. Neuhausen (238692)
- Susan M. Domchek (154078)
- Susan Slager (547068)
- SWE-BRCA (154081)
- Sylvie Mazoyer (196744)
- Teresa Ramón y Cajal (460449)
- Tereza Vaclová (547037)
- Theo A. M. van Os (395220)
- Thomas Rutherford (547060)
- Thomas V. O. Hansen (395201)
- Timothy R. Rebbeck (230766)
- Torben A. Kruse (92928)
- Trevor Cole (547049)
- Trinidad Caldés (196674)
- Uffe Birk Jensen (395267)
- Wendy Brewster (547058)
- Yael Laitman (196595)
- Yuan Chun Ding (322601)
- Publication venue
- Publication date
- Field of study
a<p>Hazard Ratio per allele (1 df) estimated from the retrospective likelihood analysis.</p>b<p>Hazard Ratio under the genotype specific models (2df) estimated from the retrospective likelihood analysis.</p>c<p>p-values were based on the score test.</p>d<p>HR per allele of 1.69 and p-trend of 1×10<sup>−4</sup> for <i>BRCA2</i> mutation carriers in stage I of the study.</p>e<p>HR per allele of 1.43 and p-trend of 0.01 for <i>BRCA1</i> mutation carriers in stage I of the study.</p>f<p>HR per allele of 1.30 and p-trend of 0.03 for <i>BRCA1</i> mutation carriers in stage I of the study.</p>g<p>HR per allele of 0.64 and p-trend of 0.057 for <i>BRCA2</i> mutation carriers in stage I of the study.</p>h<p>HR per allele of 1.25 and p-trend of 0.04 for <i>BRCA1</i> mutation carriers in stage I of the study.</p>i<p>HR per allele of 1.25 and p-trend of 0.058 for <i>BRCA2</i> mutation carriers in stage I of the study.</p>j<p>rs3093926 did not yield results under the genotype specific model due to the low minor allele frequency.</p><p>Complete description of results from stage I are included in Supplementary <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004256#pgen.1004256.s002" target="_blank">Table S1</a>.</p><p>Highlighted in bold are those SNPs showing strongest associations with breast or ovarian cancer risk (p<0.01).</p