Significant differences in activation within the anterior cingulate cortex (ACC), medial prefrontal cortex (MPFC, left and right), and superior temporal gyrus (STG) obtained with the <i>t</i>-contrast on the within-subjects analysis of variance ([<i>Self>Semantic</i>]>[<i>Other>Semantic</i>]).

<p>1 indicates Self>Semantic; 2, Other>Semantic. Activations were considered significant at <i>p</i><0.05 FDR corrected. Bars depict variance loadings and 90% confidence intervals.</p

Glass brain and rendered view depicting the main effect of task, as characterized with a one-way within-subjects ANOVA.

<p>Significant differences were recognized at <i>p</i><0.05 (FDR corrected) and extent threshold of 10 voxels.</p

Brain regions with significantly greater activation for Self-reflection, identified at <i>p</i><0.05, FDR corrected, extent threshold of at least 10 voxels.

<p>Activation in the insula is depicted in the sagittal view, plotting its differential activation as obtained with the <i>t</i>-test conducted on the within-subjects design ([<i>Self>Semantic</i>]>[<i>Other>Semantic</i>]). Bars depict variance loadings and 90% confidence intervals.</p

Brain activation differentially associated with Self and Other conditions.

<p>SMA = Supplementary Motor Area. Activations were identified with a <i>t</i>-test between [self>semantic]>[other>semantic], and vice-versa. Significance was set at <i>p</i><0.05 (FDR corrected), encompassing at least 10 voxels.</p

Neural activation produced by the main effects of task.

<p>SMA = Supplementary Motor AreaActivations were identified with a <i>t</i>-test between [self>semantic]>[other>semantic], and vice-versa. Significance was set at <i>p</i><0.05 (FDR corrected), encompassing at least 10 voxels.</p

Brain regions with significantly greater activation for Other-reflection, identified at <i>p</i><0.05, FDR corrected, extent threshold of at least 10 voxels.

<p>Activation in the precuneus is depicted in the sagittal view, plotting its differential activation as obtained with the <i>t</i>-test conducted on the within-subjects design ([<i>Other>Semantic</i>]>[<i>Self>Semantic</i>]). Bars depict variance loadings and 90% confidence intervals.</p

Mean individual severity sum and total scores, and unadjusted odds ratios (OR) with 95% confidence intervals (95% CI) for the associations of individual severity sum scores and total scores with continuation of smoking and alcohol consumption.

<p>Scores were standardized to a value ranging from 0 to 1 before entrance into logistic regression models as independent variables.</p><p>Estimates were not calculated for the category ‘domestic violence and abuse’ due to low prevalence rates.</p><p>p<0.05.</p><p>p<0.01.</p

Descriptive information of the dependent, independent and confounding variables.

<p>Chi-square tests are performed for categorical variables and one-way ANOVA analyses for continuous variables.</p

Multivariable associations between intelligence and telomere length at T3.

1<p>Age in years at T2.</p>2<p>Body mass index in kg/m².</p>3<p>Smoking in number of cigarettes/day with “0” = 0, “1” = 1–5, “2” = 6–10, “3” = 11–15, “4” = 16–20”, “5” = >20.</p>4<p>Frequency of exercise with “0” = no exercise, “1” = once/week, “2” = twice or more/week.</p>5<p>Educational level with “1” = none, “2” = low, “3” =  middle, “4” = high.</p>6<p>Work situation with “1” = unwillingly unemployed, “2” = willingly unemployed, “3” = employed.</p>7<p>Household income divided by the square root of number of people living with this income.</p

Receiver Operating Characteristics curve of the Child Behavior Checklist-Mania Scale for Bipolar Disorder vs. healthy TRAILS participants.

<p>Receiver Operating Characteristics curve of the Child Behavior Checklist-Mania Scale for Bipolar Disorder vs. healthy TRAILS participants.</p