Antiviral Effects of a Synthetic Aluminium-Magnesium Silicate on Avian Influenza Virus

Effects of a synthetic Aluminium-Magnesium Silicate (AMS) on Avian Influenza Virus (AIV) were tested. Equal amounts of H5N1 AIV samples and of AMS were mixed, left one hour, at room temperature before centrifuging. The supernatants were remeasured and tested for viral titre, for Mean Death Time (MDT) and Embryo Mortality Rate (EMR) of chicken eggs. Volumes of the viral samples reduced at rate of 23.4 ± 5.48 %. Viral titres reduced significantly (P from HA, 73 ± 32.72 to 1.4 ±0.43). Also, mortality of infected embryos reduced from 100 % to 65% while MDT of those that died, increased significantly (P = 0.001) from 76 ± 4.38 to 130 ±17.27 hours. When incubation with AMS was repeated on portions of the same sample, MDT increased from 64 to 104 hours with the portion incubated once. Two AIV portions on which incubation with AMS was repeated could not kill chick embryos