Univariate Cox Survival Analysis for NGAL expression.

<p>Abbreviations: NGAL, Neutrophil gelatinase-associated lipocalin; pCR, pathologic complete response; HER2, human epidermal growth factor receptor 2; E, number of events; N, total sample size.</p

Multivariate Cox Survival Analysis - Overall survival.

<p>Multivariate Cox Survival Analysis - Overall survival.</p

Multivariate Cox Survival Analysis - Disease-free survival.

<p>Multivariate Cox Survival Analysis - Disease-free survival.</p

Long-term outcome of patients depending on NGAL expression and intensity in months.

<p>(<b>A</b>) DFS in all patients by NGAL expression neg. vs. pos. (<b>B</b>) DFS in all patients by NGAL intensity 0–1 vs. 2–3. (<b>C</b>) DFS in HR positive patients by NGAL expression neg. vs. pos. (<b>D</b>) DFS in HR positive patients by NGAL intensity 0–1 vs. 2–3. (<b>E</b>) DFS in patients without pCR by NGAL expression neg. vs. pos. (<b>F</b>) OS in patients without pCR by NGAL intensity 0–1 vs. 2–3. NGAL: neutrophil gelatinase-associated lipocalin. DFS: disease-free survival. OS: overall survival. HR: hormone.</p

NGAL expression in human breast cancer tissues.

<p>(A) Negative NGAL staining (staining intensity score 0). (B) Weak NGAL staining (staining intensity score 1). (C) Moderate NGAL staining (staining intensity 2). (D) Strong NGAL staining (staining intensity 3). Original magnification: 400×.</p

Univariate Cox Survival Analysis for NGAL staining intensity.

<p>Abbreviations: NGAL: Neutrophil gelatinase-associated lipocalin. pCR: pathologic complete response. HER: human epidermal growth factor receptor; E, number of events; N, total sample size.</p

Association between NGAL-expression and clinicopathologic variables.

<p>Abbreviations: NGAL, Neutrophil gelatinase-associated lipocalin; HER2, human epidermal growth factor receptor 2.</p

Association between NGAL expression and pCR.

<p>Abbreviations: NGAL, Neutrophil gelatinase-associated lipocalin; pCR, pathologic complete response; HER2, human epidermal growth factor receptor 2.</p