Raw data associated with sample storage stability.

Raw data associated with sample storage stability.</p

Raw data associated with clinical samples in healthy dogs and dogs with cardiac disease.

Raw data associated with clinical samples in healthy dogs and dogs with cardiac disease.</p

Cardiac troponin I concentrations measured at baseline and after repeated freeze-thaw cycles.

Cardiac troponin I measured in serum from dogs utilizing the ADVIA Centaur XP High-Sensitivity Troponin I assay are depicted graphically at baseline and after six consecutive freeze-thaw cycles. Freezer storage was at -80°C. * indicates a significant difference from baseline.</p

Results of spiking recovery for the ADVIA Centaur cardiac troponin I high sensitivity assay for measurement of cardiac troponin I in serum from dogs.

Results of spiking recovery for the ADVIA Centaur cardiac troponin I high sensitivity assay for measurement of cardiac troponin I in serum from dogs.</p

Effect of age and sex on cardiac troponin I concentrations in healthy dogs.

The significant positive correlation between age and cardiac troponin I concentrations (rs = 0.80, P < 0.0001) amongst the dogs in Group 1 (Healthy) with the ADVIA Centaur XP High-Sensitivity Troponin I assay is displayed in panel A, while the lack of difference (P = 0.186) between females and males in this group is displayed in panel B.</p

Reproducibility and precision of the measurement of cardiac troponin I in canine serum using the ADVIA Centaur cardiac troponin I high sensitivity assay.

Reproducibility and precision of the measurement of cardiac troponin I in canine serum using the ADVIA Centaur cardiac troponin I high sensitivity assay.</p

Raw data associated with analytical validation of the AC-cTnI-HS assay including inter- and intra-assay variability, dilutional parallelism, spiking recovery, and limit of the blank analysis.

Raw data associated with analytical validation of the AC-cTnI-HS assay including inter- and intra-assay variability, dilutional parallelism, spiking recovery, and limit of the blank analysis.</p

Demographic data and serum cardiac troponin I concentrations in healthy dogs and dogs with cardiac disease.

Demographic data and serum cardiac troponin I concentrations in healthy dogs and dogs with cardiac disease.</p

Results for dilutional parallelism of the ADVIA Centaur cardiac troponin I high sensitivity assay for measurement of cardiac troponin I in canine serum.

Results for dilutional parallelism of the ADVIA Centaur cardiac troponin I high sensitivity assay for measurement of cardiac troponin I in canine serum.</p

Bland-Altman analysis, comparing the ADVIA Centaur XP High-Sensitivity Troponin I assay and the ADVIA Centaur TnI-Ultra assay.

Method comparison with Bland-Altman analysis revealed a mean difference of -49 pg/mL, with limits of agreement between -291 to 193 pg/mL. A proportional bias whereby the ADVIA Centaur XP High-Sensitivity Troponin I assay measured proportionally lower values than the ADVIA Centaur TnI-Ultra assay was noted.</p