2,474 research outputs found

    Partnerships, Not Parachutists, for Zika Research.

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    Les compétences en recherche documentaire, lecture et TIC chez les étudiants du collégial

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    Titre de l'Ă©cran-titre (visionnĂ© le 12 dĂ©c. 2006)Également disponible en format papie

    Les besoins informationnels en gestion de la production dans les PME : une approche autodiagnostique assisté par ordinateur

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    Operations management in manufacturing SMEs is becoming more complex and demanding (just-in-time, ISO 9000). For managers, this implies increased information needs that only computer-based systems can adequately satisfy. This article presents a prototype computer-based tool for the self-diagnostic of these needs, including the justification of the approach, strategy and method of analysis used, and its experimentation in two enterprises

    Service-Learning Reflections: Update of Service-Learning in Pennsylvania

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    The Pennsylvania Service-Learning Resource and Evaluation Network based at the University of Pittsburgh supports service-learning programs.The network provides information, support, resources,and guidance. Its philosophy is to work with people by offering systematic data of a wide variety of types that help inform them about what they care about. The primary goal of the network is to help schools and community-based organizations to evaluate their service-learning programs

    Les compétences en recherche documentaire, lecture et TIC chez les étudiants du collégial dans le secteur technique

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    Titre de l'Ă©cran-titre (visionnĂ© le 26 aoĂ»t 2008).Également disponible en format papier.Bibliogr

    Predicting facebook users online privacy protection: Risk, trust, norm focus theory, and the theory of planned behavior

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    Journal ArticleThis is an Accepted Manuscript of an article published by Taylor & Francis in The Journal of Social Psychology on 21 April 2014, available online: http://wwww.tandfonline.com/10.1080/00224545.2014.914881The present research adopts an extended theory of the planned behavior model that included descriptive norms, risk, and trust to investigate online privacy protection in Facebook users. Facebook users (N = 119) completed a questionnaire assessing their attitude, subjective injunctive norm, subjective descriptive norm, perceived behavioral control, implicit perceived risk, trust of other Facebook users, and intentions toward protecting their privacy online. Behavior was measured indirectly 2 weeks after the study. The data show partial support for the theory of planned behavior and strong support for the independence of subjective injunctive and descriptive norms. Risk also uniquely predicted intentions over and above the theory of planned behavior, but there were no unique effects of trust on intentions, nor of risk or trust on behavior. Implications are discussed. © Copyright © Taylor & Francis Group, LLC

    Low-volume jet injection for intradermal immunization in rabbits

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    BACKGROUND: This study tested a low-volume (20–30 ÎŒl/20–30 ÎŒg DNA) jet injection method for intradermal delivery of a DNA vaccine. Jet injection offers the advantages of a needle-less system, low-cost, rapid preparation of the injected DNA solution, and a simple delivery system. More than one construct can be injected simultaneously and the method may be combined with adjuvants. RESULTS: Low-volume jet injection targeted delivery of a DNA solution exclusively to the dermis and epidermis of rabbits. A three injection series of plasmid DNA, encoding the Hepatitis B Surface Antigen stimulated a humoral immune response in 2/5 rabbits. One rabbit developed a significant rise in antibody titer after 1 injection and one following 2 injections. There were no significant differences between jet injection and particle bombardment in the maximal antibody titers or number of injections before response. A three injection series of the same plasmid DNA by particle bombardment elicited a significant rise in antibody titer in 3/5 rabbits. One rabbit developed antibody after 1 injection and two after 3 injections. In contrast, 0/5 rabbits receiving DNA by needle and syringe injection responded. In the jet injection and particle bombardment groups, gene expression levels in the skin did not predict response. While immune responses were similar, luciferase gene expression levels in the skin following particle bombardment were 10–100 times higher than jet injection. CONCLUSION: Low-volume jet injection is a simple, effective methodology for intradermal DNA immunization

    Continued circulatory support: effect of epinephrine or dopamine on 24-hour survival and neurologic function in dogs

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    The effects on 24-h survival and neurologic function were compared following continued postresuscitation circulatory support with epinephrine or dopamine. Cardiopulmonary arrest was induced by ventricular fibrillation. After 10 min, resuscitation efforts were initiated including i.v. infusion of either epinephrine (6 [mu]g/kg per min, 11 dogs) or dopamine (10 [mu]g/kg per min, 14 dogs) for continued circulatory support. There was no difference detected in duration of circulatory support, although dogs receiving epinephrine required more lidocaine (3.3 +/- 0.4 vs. 1.8 +/- 0.3 mg/kg, P = 0.005). Likewise, there was no statistically significant difference detected in MAP or HR between groups at any time tested. However, dogs receiving epinephrine had significantly worse neurologic function at 6 and 12 h postarrest. Mean survival time (20.3 +/- 1.2 vs. 15.3 +/- 1.9 h, P = 0.028) and overall survival (P = 0.027, survival curve analysis) were significantly longer for dogs receiving dopamine. Plasma glucose in the first 6 h postarrest was significantly higher in dogs receiving epinephrine (P = 0.006). These results suggest that the use of epinephrine for continued vasopressor support in cardiopulmonary resuscitation may contribute to decreased survival and poorer neurologic function in this controlled experimental setting. It is reasonable to propose that similar responses to these commonly used circulatory support agents occur clinically. Therefore, continued vasopressor support with dopamine rather than epinephrine may be justified in the setting of cardiac resuscitation.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/27916/1/0000339.pd
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