Vanishing viscosity limits for the degenerate lake equations with Navier boundary conditions

The paper is concerned with the vanishing viscosity limit of the two-dimensional degenerate viscous lake equations when the Navier slip conditions are prescribed on the impermeable boundary of a simply connected bounded regular domain. When the initial vorticity is in the Lebesgue space $L^q$ with $2<q\le\infty$, we show the degenerate viscous lake equations possess a unique global solution and the solution converges to a corresponding weak solution of the inviscid lake equations. In the special case when the vorticity is in $L^\infty$, an explicit convergence rate is obtained

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead