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Nanoslit Confined DNA at Low Ionic Strengths
We present nanoslit confined DNA
conformations at very low ionic
strengths and a theory to explain most measurements for single DNA
molecule size under strong nanoslit confinement. Very low ionic strength
conditions not only increase the DNA persistence length dramatically,
but also cause DNA molecules to swell to the extent that the effective
diameter of DNA becomes larger than the nanoslit height. By accounting
for these effects, our results and theory provide a reasonable clue
for a current controversy regarding the dependence of the DNA conformation
on slit height (<i>h</i>), persistence length (<i>p</i>), and effective diameter (<i>w</i>)