Associations between VDR polymorphisms (ApaI, BsmI, Cdx-2, FokI, TaqI) and the risk of ovarian cancer under different genetic models.

<p>Associations between VDR polymorphisms (ApaI, BsmI, Cdx-2, FokI, TaqI) and the risk of ovarian cancer under different genetic models.</p

Characteristics of publications identified for the meta-analysis.

<p><b>Abbreviations:</b> PB, population-based case-control study; NCC, nested case-control study; PCR-RFLP, polymerase chain reaction-restriction fragment length polymorphism; NECC, new England case-control study; NHS, nurses’ health study; WHS, women’s health study; MALOVA, malignant ovarian cancer study; SEARCH, studies of epidemiology and risk factors in cancer heredity: ovarian cancer study; GEOCS, genetic epidemiology of ovarian cancer study; HAW, Hawaii ovarian cancer study; UKOPS, united kingdom ovarian cancer population study.</p

Forest plot for the association between variant FokI in the VDR and risk of ovarian cancer (CT vs. CC).

<p>NECC, new England case-control study; NHS, nurses’ health study; WHS, women’s health study; MALOVA, malignant ovarian cancer study; SEARCH, studies of epidemiology and risk factors in cancer heredity: ovarian cancer study; GEOCS, genetic epidemiology of ovarian cancer study; UKOPS, united kingdom ovarian cancer population study.</p

Forest plot for the association between variant FokI in the VDR and risk of ovarian cancer (TT vs. CC).

<p>NECC, new England case-control study; NHS, nurses’ health study; WHS, women’s health study; MALOVA, malignant ovarian cancer study; SEARCH, studies of epidemiology and risk factors in cancer heredity: ovarian cancer study; GEOCS, genetic epidemiology of ovarian cancer study; UKOPS, united kingdom ovarian cancer population study.</p

Flow chart for the literature search in the meta-analysis.

<p>Flow chart for the literature search in the meta-analysis.</p

The inhibition curve of some organophosphorus and carbamate pesticides.

<p>The yeast with AChE expression were collected, re-suspended in PBS buffer and seeded in 96-well plate. After incubation with various concentrations of different pesticides, the remaining enzyme activities were determined. Error bars represent the standard deviation of mean values.</p

The identification of PCR constructs.

<p>The identification of PCR constructs.</p

Analysis of the growth of yeast and the induced expression of AChE in different culture conditions.

<p>After induction in SC (A) and YPD (B) medium with 1%, 2%, or 4% of galactose for different time periods, the OD₆₀₀ values of yeast suspension were determined. After induction in SC (C) and YPD (D) minimal medium with 1%, 2%, or 4% of galactose for different time periods, the cultures were harvested and the relative enzyme activity of induced AChE was determined. Error bars represent the standard deviation of mean values.</p

Primers used in this study.

<p>Primers used in this study.</p

The construction of plasmid pYES-DEST52.

<p>The construction of plasmid pYES-DEST52.</p