Manifested psychiatric adverse events and levetiracetam dosages at the point of the symptoms occurrence.

<p>Manifested psychiatric adverse events and levetiracetam dosages at the point of the symptoms occurrence.</p

Demographics and clinical characteristics of the patients with levetiracetam-induced psychiatric adverse events.

<p>Demographics and clinical characteristics of the patients with levetiracetam-induced psychiatric adverse events.</p

In-silico modeling of the molecular interaction between HLA-A*1101 and LEV.

<p>The LEV molecule was predicted to be docked into the P1 pocket of HLA-A*1101 with relatively higher affinity (5.1 kcal/mol) compared to other HLA-A subtypes. HLA, human leukocyte antigen; LEV, levetiracetam.</p

Additional file 1: Table S1. of Orthostatic intolerance symptoms are associated with depression and diminished quality of life in patients with postural tachycardia syndrome

Correlations among the questionnaire parameters (full details). Table S2. Univariate analysis for a significant functional deterioration. (DOCX 34 kb

Additional file 1: Table S1. of Orthostatic intolerance symptoms are associated with depression and diminished quality of life in patients with postural tachycardia syndrome

Correlations among the questionnaire parameters (full details). Table S2. Univariate analysis for a significant functional deterioration. (DOCX 34 kb

Human leukocyte antigen genotype of the patients with levetiracetam-induced psychiatric adverse events.

<p>Human leukocyte antigen genotype of the patients with levetiracetam-induced psychiatric adverse events.</p

Daily frequency of spontaneous recurrent seizures in all individual mice.

<p>The seizure frequencies (spontaneous recurrent seizures/day) in individual mice are represented by the gray bar: light color indicates a low seizure frequency, and dark color indicates a high seizure frequency. The start and end of the monitoring period are marked by the vertical dotted lines. (A) Chronic phase 1. (B) Chronic phase 2. SE = status epilepticus, SRS = spontaneous recurrent seizure.</p

Scatter plots of various parameters.

<p>Scatter plots of cluster duration vs total number of spontaneous recurrent seizures during a single cluster (A), cluster duration vs duration of the following seizure-free period (B), number of days from cluster onset to the day of peak seizure frequency vs peak seizure frequency (C), and number of days from cluster onset to the day of peak seizure frequency vs number of days from the day of peak seizure frequency to cluster end (D). The dotted line represents a slope of 1.</p

Comparison of characteristics of spontaneous recurrent seizures with a previous study using our definition of seizure cluster.

<p>Comparison of characteristics of spontaneous recurrent seizures with a previous study using our definition of seizure cluster.</p

Characteristics of spontaneous recurrent seizures in a mouse pilocarpine-induced epilepsy model in chronic phase.

<p>Characteristics of spontaneous recurrent seizures in a mouse pilocarpine-induced epilepsy model in chronic phase.</p