3,703 research outputs found

    How Can Learning & Development be Applied to Support Employees\u27 Changing Career Paths?

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    Employees change their career path for reasons such as passion, opportunities, and interests. Companies need to prepare to support this career transition in order to improve the efficiency of the organizations. One of the most effective ways to support this transition is through learning and development. This year\u27s Global Human Capital Trends survey shows that more than 85 percent of respondents cited learning as important or very important. Yet, more companies than ever report that they are unprepared to meet this challenge [1]. To close gaps between career transition needs and lack of preparation in organizations, HR professionals and learning specialists are being asked to offer better learning platforms and products that meet new expectations of employees for on-demand learning opportunities

    Stewardship and almsgiving : a study in Luke's theology of wealth

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    This thesis starts with questions over Luke's idea of the relation between wealth and discipleship. Previous attempts are found to have failed to reconcile the matter of wealth and poverty with the theme of discipleship in Luke's theology. This failure motivates us to investigate a new paradigm, that is, stewardship. The following are the results that we have gained through our exploration. 1. With regard to the Sitz im Leben of Luke-Acts, it has been revealed that Luke's community would have been located in a urban setting steeped in the Hellenistic culture somewhere in the Roman East around the end of the first century A.D., and its members would have consisted of Gentiles in terms of their ethnic background, and in view of their socio-economic status, the rich and the poor who represented both extreme ends of the spectrum of contemporary society. 2. While Mark demands literal renunciation of wealth from Jesus' disciples which arises from his idea of discipleship, Luke wants Jesus' disciples to surrender the ownership of their wealth. 3. Luke wants to define the relation between God and his people as that of master and slave, rather than the teacher-pupil relation that constitutes a basic element of Markan discipleship. 4. When these two motifs unique to Luke are combined, it emerges that stewardship is a main motif that Luke wants his congregations to consider, particularly when they are asked to deal with material possessions (Lk 12.42-48; 16.1-13; 19.11-27). 5. Almsgiving is suggested as a proper way that Christians should use their wealth when this stewardship is adequately applied. An appeal to almsgiving appears to be the ultimate aim that Luke intends when he incorporates into his Gospel so much material on wealth

    Ethanol Extract of Dianthus chinensis L. Induces Apoptosis in Human Hepatocellular Carcinoma HepG2 Cells In Vitro

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    Dianthus chinensis L. is used to treat various diseases including cancer; however, the molecular mechanism by which the ethanol extract of Dianthus chinensis L. (EDCL) induces apoptosis is unknown. In this study, the apoptotic effects of EDCL were investigated in human HepG2 hepatocellular carcinoma cells. Treatment with EDCL significantly inhibited cell growth in a concentration- and time-dependent manner by inducing apoptosis. This induction was associated with chromatin condensation, activation of caspases, and cleavage of poly (ADP-ribose) polymerase protein. However, apoptosis induced by EDCL was attenuated by caspase inhibitor, indicating an important role for caspases in EDCL responses. Furthermore, EDCL did not alter the expression of bax in HepG2 cells but did selectively downregulate the expression of bcl-2 and bcl-xl, resulting in an increase in the ratio of bax:bcl-2 and bax:bcl-xl. These results support a mechanism whereby EDCL induces apoptosis through the mitochondrial pathway and caspase activation in HepG2 cells

    Increased Risk of Ischemic Stroke during Sleep in Apneic Patients.

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    BACKGROUND AND PURPOSE:The literature indicates that obstructive sleep apnea (OSA) increases the risk of ischemic stroke. However, the causal relationship between OSA and ischemic stroke is not well established. This study examined whether preexisting OSA symptoms affect the onset of acute ischemic stroke. METHODS:We investigated consecutive patients who were admitted with acute ischemic stroke, using a standardized protocol including the Berlin Questionnaire on symptoms of OSA prior to stroke. The collected stroke data included the time of the stroke onset, risk factors, and etiologic subtypes. The association between preceding OSA symptoms and wake-up stroke (WUS) was assessed using multivariate logistic regression analysis. RESULTS:We identified 260 subjects with acute ischemic strokes with a definite onset time, of which 25.8% were WUS. The presence of preexisting witnessed or self-recognized sleep apnea was the only risk factor for WUS (adjusted odds ratio=2.055, 95% confidence interval=1.035-4.083, p=0.040). CONCLUSIONS:Preexisting symptoms suggestive of OSA were associated with the occurrence of WUS. This suggests that OSA contributes to ischemic stroke not only as a predisposing risk factor but also as a triggering factor. Treating OSA might therefore be beneficial in preventing stroke, particularly that occurring during sleep
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