NLO QCD corrections to Single Top and W associated production at the LHC with forward detector acceptances

In this paper we study the Single Top and W boson associated photoproduction via the main reaction $\rm pp\rightarrow p\gamma p\rightarrow pW^{\pm}t+Y$ at the 14 TeV Large Hadron Collider (LHC) up to next-to-leading order (NLO) QCD level assuming a typical LHC multipurpose forward detector. We use the Five-Flavor-Number Schemes (5FNS) with massless bottom quark assumption in the whole calculation. Our results show that the QCD NLO corrections can reduce the scale uncertainty. The typical K-factors are in the range of 1.15 to 1.2 which lead to the QCD NLO corrections of 15$$ to 20$$ correspond to the leading-order (LO) predictions with our chosen parameters.Comment: 41pages, 12figures. arXiv admin note: text overlap with arXiv:1106.2890 by other author

The Arabidopsis EAR-motif-containing protein RAP2.1 functions as an active transcriptional repressor to keep stress responses under tight control

<p>Abstract</p> <p>Background</p> <p>Plants respond to abiotic stress through complex regulation of transcription, including both transcriptional activation and repression. Dehydration-responsive-element binding protein (DREB)-type transcription factors are well known to play important roles in adaptation to abiotic stress. The mechanisms by which DREB-type transcription factors activate stress-induced gene expression have been relatively well studied. However, little is known about how DREB-type transcriptional repressors modulate plant stress responses. In this study, we report the functional analysis of RAP2.1, a DREB-type transcriptional repressor.</p> <p>Results</p> <p>RAP2.1 possesses an APETALA2 (AP2) domain that binds to dehydration-responsive elements (DREs) and an ERF-associated amphiphilic repression (EAR) motif, as the repression domain located at the C-terminus of the protein. Expression of <it>RAP2.1 </it>is strongly induced by drought and cold stress via an ABA-independent pathway. Arabidopsis plants overexpressing <it>RAP2.1 </it>show enhanced sensitivity to cold and drought stresses, while <it>rap2.1-1 </it>and <it>rap2.1-2 </it>T-DNA insertion alleles result in reduced sensitivity to these stresses. The reduced stress sensitivity of the plant containing the <it>rap2.1 </it>allele can be genetically complemented by the expression of <it>RAP2.1</it>, but not by the expression of EAR-motif-mutated <it>RAP2.1</it>. Furthermore, chromatin immunoprecipitation (ChIP) analysis has identified <it>Responsive to desiccation/Cold-regulated </it>(<it>RD/COR</it>) genes as downstream targets of RAP2.1 <it>in vivo</it>. Stress-induced expression of the <it>RD/COR </it>genes is repressed by overexpression of <it>RAP2.1 </it>and is increased in plants expressing the <it>rap2.1 </it>allele. In addition, RAP2.1 can negatively regulate its own expression by binding to DREs present in its own promoter. Our data suggest that RAP2.1 acts as a negative transcriptional regulator in defence responses to cold and drought stress in Arabidopsis.</p> <p>Conclusions</p> <p>A hypothetical model for the role of RAP2.1 in modulating plant responses to cold and drought is proposed in this study. It appears that RAP2.1 acts as a negative "subregulon" of DREB-type activators and is involved in the precise regulation of expression of stress-related genes, acting to keep stress responses under tight control.</p

Tetra­kis(1-allyl-1H-imidazole-κN 3)bis­(thio­cyanato-κN)manganese(II)

The structure of the title compound, [Mn(NCS)2(C6H8N2)4], consists of isolated mol­ecules of [Mn(NCS)2(Aim)4] (Aim = 1-allyl­imidazole), which contain a compressed octa­hedral MnN6 chromophore (site symmetry ). The NCS− anions are trans and four N atoms from the Aim ligands define the equatorial plane. The mean Mn—N(Aim) and Mn—N(NCS) distances are 2.270 and 2.229 Å, respectively. Weak C—H⋯N inter­actions contribute to the crystal packing stability

Comparison of capecitabine and tegafur/gimeracil/oteracil (S-1) in the treatment of advanced breast carcinoma in the elderly

Purpose: To analyse and compare the clinical effects and safety of capecitabine and tegafur/gimeracil/oteracil (S-1) in the treatment of advanced breast carcinoma.Methods: Eighty-four metastatic breast cancer elderly patients for whom first or second-line treatment had failed, were selected from among those admitted to the oncology ward of Binjiang People’s Hospital, China between January 2014 and June 2015. They were randomly divided into S-1 group (n =41) and capecitabine group (n = 41) and received varying doses of those drugs  according to body surface area. Clinical effects, progression-free survival, and incidence of adverse reactions were compared for the two groups following treatment.Results: Disease control rate (CR) in S-1 group was 55.6 %, much higher than 35.1 % observed for capecitabine group (p &lt; 0.05). The disease control rate for the S-1 group was 93.7 %, also much higher than the 70.6 % found in capecitabine group. Survival analysis showed that the median survival times of the two groups did not differ significantly (p &gt; 0.05). Furthermore, some adverse reactions such as myelosuppression and lack of strength, did not differ significantly between the two groups (p &gt; 0.05), whereas others, including leukopenia, nausea and vomiting and hand-foot syndrome were more serious and frequent in capecitabine group than in S-1 group (p &lt; 0.05).Conclusion: Monotherapy with S-1 is more effective than that with capecitabine. Adverse reactions are minimal for both drugs.Keywords: Breast carcinoma, Capecitabine, S-1, Adverse reactions,  Myelosuppression, Leukopenia, Hand-foot syndrom

Clinical observation of macular grid photocoagulation before cataract surgery for diabetes patients with diffuse macular edema

AIM: To explore the effects and reliability of macular grid photocoagulation before cataract surgery for diabetes patients with diffuse macular edema.<p>METHODS: A total of 30 patients(40 eyes)were enrolled in the study. All the patients were randomly divided into two groups: group A: 20 eyes were treated with macular grid photocoagulation before cataract surgery; group B: 20 eyes were treated with cataract surgery only. <p>RESULTS: The patients treated with macular grid photocoagulation before cataract surgery. Postoperative visual acuity was improved, the edema of macular decreased. The patients treated with cataract surgery only, visual acuity showed no evident change and macular edema remained stable or creased. <p>CONCLUSION: Macular grid photocoagulation before cataract surgery for diabetes patients can improve the outcome and vision of the patients

Effects of Vanadium doping on BaFe2As2

We report an investigation of the structural, magnetic and electronic properties of Ba(Fe(1-x)V(x))2As2 using x-ray, transport, magnetic susceptibility and neutron scattering measurements. The vanadium substitutions in Fe sites are possible up to 40\%. Hall effect measurements indicate strong hole-doping effect through V doping, while no superconductivity is observed in all samples down to 2K. The antiferromagnetic and structural transition temperature of BaFe2As2 is gradually suppressed to finite temperature then vanishes at x=0.245 with the emergence of spin glass behavior, suggesting an avoided quantum critical point (QCP). Our results demonstrate that the avoided QCP and spin glass state which were previously reported in the superconducting phase of Co/Ni-doped BaFe2As2 can also be realized in non-superconducting Ba(Fe(1-x)V(x))2As2.Comment: 5 pages, 6 figure

Immune responses of Helicoverpa armigera to different kinds of pathogens

<p>Abstract</p> <p>Background</p> <p>Insects react against pathogens through innate immunity. The cotton bollworm <it>Helicoverpa armigera </it>(<it>H. armigera</it>) is an important defoliator and an extremely destructive pest insect of many crops. The elucidation of the mechanism of the immune response of <it>H. armigera </it>to various pathogens can provide a theoretical basis for new approaches to biologically control this pest.</p> <p>Results</p> <p>Four kinds of pathogens <it>Bacillus thuringiensis</it>, <it>Klebsiella pneumoniae</it>, <it>Candida albicans</it>, and <it>Autographa californica </it>multiple nucleocapsid nucleopolyhedrovirus harbored green fluorescence protein and polyhedron (<it>Ac</it>MNPV-GFP) were used to challenge the insect. The cellular and humoral immune responses to the pathogens were analyzed in the challenged <it>H. armigera</it>. The results show that in the five kinds of haemocytes, only granulocytes phagocytized the Gram-negative and Gram-positive bacteria and fungi. All haemocytes can be infected by <it>Ac</it>MNPV. Fourteen immune-related genes including pattern recognition receptors (PRRs) such as peptidoglycan recognition proteins (<it>HaPGRP </it>and <it>HaPGRP C</it>) and Gram-Negative Bacteria-Binding Protein (<it>HaGNBP</it>), and antimicrobial peptides (AMPs) such as <it>cecropin-1, 2 </it>and <it>3 </it>(<it>HaCec-1, 2 </it>and <it>3</it>), <it>lysozyme </it>(<it>HaLys</it>), attacin (<it>HaAtt</it>), <it>gallerimycin-like </it>(<it>HaGall</it>), <it>gloverin-like </it>(<it>HaGlo</it>), <it>moricin-like </it>(<it>HaMor</it>), cobatoxin-like (<it>HaCob</it>), <it>galiomicin-like </it>(<it>HaGali</it>), and <it>immune inducible protein </it>(<it>HaIip</it>) appeared in different expression profiles to different pathogen infections. The transcripts of 13 immune related genes (except <it>HaPGRPC</it>) are obviously up-regulated by Gram-positive bacteria. <it>HaCec-1 and 3, HaMor, HaAtt, HaLys</it>, <it>HaIip</it>, <it>HaPGRP </it>and <it>HaGNBP </it>are greatly up-regulated after fungal infection. <it>HaGNBP, HaCec-2, HaGall, HaGlo, HaMor, HaCob, HaGali </it>obviously increased in Gram-negative bacterial infection. Only five genes, <it>HaGNBP, HaCec-1</it>, <it>HaGali</it>, <it>HaGlo</it>, and <it>HaLys</it>, are weakly up-regulated after viral infection. The AMP transcripts had higher expression levels than the PRR transcripts after the microbial challenge.</p> <p>Conclusions</p> <p>These data suggest that the granulocytes are the major phagocytes in <it>H. armigera</it>. All haemocytes can be infected by <it>Ac</it>MNPV. The transcripts of 14 immune related genes have different expression patterns in <it>H. armigera </it>infected by different pathogens, which means that the immune-related genes may have different functions against various kinds of pathogens.</p

Flank gland-secreted putative chemosignals pertaining to photoperiod, endocrine states, and sociosexual behavior in golden hamsters

Behavioral studies have shown that flank glands are involved in chemical communication in golden hamsters Mesocricetus auratus but little chemical analysis has been conducted on volatiles arising from these glands. Using gas chromatography- mass spectrometry, we detected compounds from the flank glands of males, only eight of which were also produced in females. Based on these chemical data we performed a number of further experiments. By manipulating light we found that males exposed to short-photoperiods developed smaller flank glands than those exposed to long-photoperiods. Six flank gland volatiles reduced in relative abundance, which possibly coded for reproductive status of males of this seasonally breeding hamster species. Through dyadic encounters, we were able to induce the formation of dominant-subordinate relationships and show that two glandular compounds became high in relative abundance and may function as dominance pheromones. Castration eliminated all male-specific compounds resulting from flank glands, but bilateral ovariectomies only affected one compound in females. Once these ovariectomized females were treated with testosterone, their glandular compounds resembled those of males, suggesting these compounds are under the main control of androgen. Two female putative pheromones, tetradecanoic acid and hexadecanoic acid, were used in binary choice tests and were both found to attract males over females. Applying a solution of these pheromone compounds to adult males also suppressed their agonistic behavior

Anesthetic and hemodynamic effects of etomidateremifentanil combination in laparoscopic surgery

Purpose: To study the anesthetic and hemodynamic effects of etomidate-remifentanil combination treatment in laparoscopic surgery.Methods: Patients scheduled for gynecological laparoscopic surgery (n = 120) were assigned to test and control groups (60 patients each). Etomidate combined with remifentanil anesthesia was used in the test group, while propofol-remifentanil combination anesthesia was used in the control group. The effect of anesthesia on awakening time, extubation time, pain relief time, systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) of patients before and after the extubation were observed and recorded for the two groups.Results: Excellent rating was 98.0 % in the test group, and was superior to the corresponding rating of 86.0 % in the control group. Anesthesia time, awakening time, extubation time and pain relief time were markedly shorter in the test group than in controls (p &lt; 0.05). However, there were no significant differences in SBP, DBP and HR of patients with tracheal intubation between the two groups (p &gt; 0.05). The results were similar in patients with laparoscopic placement. After laparoscopic placement and tracheal extubation, significant decreases in SBP and HR in the test group were seen, relative to control patients (p &lt; 0.05).Conclusion: The anesthetic effect of etomidate combined with remifentanil is superior to that of propofol and remifentanil, and ensures stability of hemodynamic parameters such as SBP, DBP and HR during the period of anesthesia.Keywords: Etomidate, Remifentanil, Propofol, Laparoscopic surgery, Hemodynamic parameter