5,538 research outputs found
Angle-of-Arrival Estimation with Practical Phone Antenna Configurations
With the advances of the Internet of Things and mobile connectivity, location-based services are becoming increasingly popular and continue to enhance our experience. Multiple antennas have been pivotal in providing reliable wireless communications and high-resolution localization. If the antennas of the array are isotropic, then the simplified array manifold determined by the array geometry can be used to estimate the angle-of-arrival (AOA). However, in the real world, mobile handsets tend to have very limited space, where the practical antennas are equipped on the same ground plane, and the array geometry hardly obeys the rule of half-wavelength spacing. Therefore, a practical antenna couples signals from other antennas, causing a mutual coupling effect. Complex array manifolds are produced on an antenna even if the received signal is propagated through a single path channel. In addition, the irregular radiation pattern of each antenna further impairs the AOA estimation capability. Given the above effects, the simplified array manifold determined by the array geometry can no longer provide precise localization. In this paper, we propose a generic array manifold model for both isotropic and practical antennas. We also present an efficient algorithm to enable AOA estimation on practical antennas on the basis of the proposed model and implement it on a 5G phone at a mid-band spectrum with a 100MHz channel bandwidth. Results reveal the promising performance of the proposed model, with the AOA estimation errors lower than 10∘ in over 90% of the scenarios
Effects of different doses of melamine in the diet on melamine concentrations in milk, plasma, rumen fluid, urine and feces in lactating dairy cows
The objectives of this paper were to evaluate the effects of feeding diets containing different levels of melamine on melamine concentrations in milk, plasma, rumen fluid, urine and feces in Holstein dairy cows. Sixteen Chinese Holstein dairy cows fixed with permanent ruminal cannulas were assigned to 1 of 4 treatments within a completely randomized design for 10 days. Cows were fed different amounts of melamine {20 (group 1), 40 (group 2), 60 (group 3) or 80 (group 4) g/day/cow} once daily in the morning mixed with a melamine free basal diet for 7-days adaptation followed by 3-days urine and feces sample collections. Melamine was found in all samples tested and its concentration generally increased as dose increased in the diet. These results indicated that different doses of melamine in the diet could result in different concentrations of melamine in milk, plasma, rumen fluid, urine and feces. Data suggested that melamine primarily cleared by urinary excretion, followed by fecal excretion in lactating dairy cows. Mammary tissue was apparently not a major tissue to dispose melamine, especially when fed a relatively low dose (lower than 40 g/day/cow).Key words: Melamine, excretion, lactating dairy cow
Nucleosynthesis in Advective Accretion Disks Around Galactic and Extra-Galactic Black Holes
We compute the nucleosynthesis of materials inside advective disks around
black holes. We show that composition of incoming matter can change
significantly depending on the accretion rate and accretion disks. These works
are improvements on the earlier works in thick accretion disks of Chakrabarti,
Jin & Arnett (1987) in presence of advection in the flow.Comment: Latex pages including figures. Kluwer Style files included. Appearing
in `Observational Evidence for Black Holes in the Universe', ed. Sandip K.
Chakrabarti, Kluwer Academic Publishers (DORDRECHT: Holland
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Icosahedral and dodecagonal quasicrystal plus glass alloys with plastic deformability
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NALP1 in vitiligo-associated multiple autoimmune disease.
BACKGROUND: Autoimmune and autoinflammatory diseases involve interactions between genetic risk factors and environmental triggers. We searched for a gene on chromosome 17p13 that contributes to a group of epidemiologically associated autoimmune and autoinflammatory diseases. The group includes various combinations of generalized vitiligo, autoimmune thyroid disease, latent autoimmune diabetes in adults, rheumatoid arthritis, psoriasis, pernicious anemia, systemic lupus erythematosus, and Addison's disease. METHODS: We tested 177 single-nucleotide polymorphisms (SNPs) spanning the 17p13 linkage peak for association with disease and identified a strong candidate gene. We then sequenced DNA in and around the gene to identify additional SNPs. We carried out a second round of tests of association using some of these additional SNPs, thus elucidating the association with disease in the gene and its extended promoter region in fine detail. RESULTS: Association analyses resulted in our identifying as a candidate gene NALP1, which encodes NACHT leucine-rich-repeat protein 1, a regulator of the innate immune system. Fine-scale association mapping with the use of DNA from affected families and additional SNPs in and around NALP1 showed an association of specific variants with vitiligo alone, with an extended autoimmune and autoinflammatory disease phenotype, or with both. Conditional logistic-regression analysis of NALP1 SNPs indicated that at least two variants contribute independently to the risk of disease. CONCLUSIONS: DNA sequence variants in the NALP1 region are associated with the risk of several epidemiologically associated autoimmune and autoinflammatory diseases, implicating the innate immune system in the pathogenesis of these disorders
Effect of gold coating on sensitivity of rhombic silver nanostructure array
The sensitivity is the most important parameter in the sensing field. Effort was made to study the effect of gold coating on the sensitivity of rhombic silver nanostructure array through numerical simulation using the discrete dipole approximation method. This study shows that thickness of the gold coating can be varied to tune the sensitivity of the rhombic silver nanostructure array. The Au-Ag nanostructure array is found to possess the maximum refractive index sensitivity of 714 nm/RIU when thickness of gold is 20 nm, thickness of silver is 25 nm, and refractive index of the medium is around 1.35. The condition for achieving the maximum refractive index sensitivity can be used for detecting many species of biomolecules and drugs in the future
Dynamic model for piezotronic and piezo-phototronic devices under low and high frequency external compressive stresses (Featured)
In this work, we aim to establish a theoretical method for modelling the dynamic characteristics of piezotronics and piezo-phototronic devices. By taking the simplest piezotronic device, PN junction as an example, we combine the small signal model and the unified approach to investigate its diffusion capacitance and conductance when it is under both low and high frequency external compressive stresses. This approach is different from the traditional considerations that treat the piezopotential as a static value. Furthermore, we expand the theory into piezo-phototronic devices, e.g., a light emitting diode. The dynamic recombination rate and light emitting intensity are quantitatively calculated under different frequencies of external compressive stresses
Mathematically Gifted Adolescents Have Deficiencies in Social Valuation and Mentalization
Many mathematically gifted adolescents are characterized as being indolent, underachieving and unsuccessful despite their high cognitive ability. This is often due to difficulties with social and emotional development. However, research on social and emotional interactions in gifted adolescents has been limited. The purpose of this study was to observe differences in complex social strategic behaviors between gifted and average adolescents of the same age using the repeated Ultimatum Game. Twenty-two gifted adolescents and 24 average adolescents participated in the Ultimatum Game. Two adolescents participate in the game, one as a proposer and the other as a responder. Because of its simplicity, the Ultimatum Game is an apt tool for investigating complex human emotional and cognitive decision-making in an empirical setting. We observed strategic but socially impaired offers from gifted proposers and lower acceptance rates from gifted responders, resulting in lower total earnings in the Ultimatum Game. Thus, our results indicate that mathematically gifted adolescents have deficiencies in social valuation and mentalization
Creation of ultracold molecules from a Fermi gas of atoms
Since the realization of Bose-Einstein condensates (BEC) in atomic gases an
experimental challenge has been the production of molecular gases in the
quantum regime. A promising approach is to create the molecular gas directly
from an ultracold atomic gas; for example, atoms in a BEC have been coupled to
electronic ground-state molecules through photoassociation as well as through a
magnetic-field Feshbach resonance. The availability of atomic Fermi gases
provides the exciting prospect of coupling fermionic atoms to bosonic
molecules, and thus altering the quantum statistics of the system. This
Fermi-Bose coupling is closely related to the pairing mechanism for a novel
fermionic superfluid proposed to occur near a Feshbach resonance. Here we
report the creation and quantitative characterization of exotic, ultracold
K molecules. Starting with a quantum degenerate Fermi gas of atoms
at T < 150 nanoKelvin we scan over a Feshbach resonance to adiabatically create
over a quarter million trapped molecules, which we can convert back to atoms by
reversing the scan. The small binding energy of the molecules is controlled by
detuning from the Feshbach resonance and can be varied over a wide range. We
directly detect these weakly bound molecules through rf photodissociation
spectra that probe the molecular wavefunction and yield binding energies that
are consistent with theory
Coordination of opposing sex-specific and core muscle groups regulates male tail posture during Caenorhabditis elegans male mating behavior
Background
To survive and reproduce, animals must be able to modify their motor behavior in response to changes in the environment. We studied a complex behavior of Caenorhabditis elegans, male mating behavior, which provided a model for understanding motor behaviors at the genetic, molecular as well as circuit level. C. elegans male mating behavior consists of a series of six sub-steps: response to contact, backing, turning, vulva location, spicule insertion, and sperm transfer. The male tail contains most of the sensory structures required for mating, in addition to the copulatory structures, and thus to carry out the steps of mating behavior, the male must keep his tail in contact with the hermaphrodite. However, because the hermaphrodite does not play an active role in mating and continues moving, the male must modify his tail posture to maintain contact. We provide a better understanding of the molecular and neuro-muscular pathways that regulate male tail posture during mating.
Results
Genetic and laser ablation analysis, in conjunction with behavioral assays were used to determine neurotransmitters, receptors, neurons and muscles required for the regulation of male tail posture. We showed that proper male tail posture is maintained by the coordinated activity of opposing muscle groups that curl the tail ventrally and dorsally. Specifically, acetylcholine regulates both ventral and dorsal curling of the male tail, partially through anthelmintic levamisole-sensitive, nicotinic receptor subunits. Male-specific muscles are required for acetylcholine-driven ventral curling of the male tail but dorsal curling requires the dorsal body wall muscles shared by males and hermaphrodites. Gamma-aminobutyric acid activity is required for both dorsal and ventral acetylcholine-induced curling of the male tail and an inhibitory gamma-aminobutyric acid receptor, UNC-49, prevents over-curling of the male tail during mating, suggesting that cross-inhibition of muscle groups helps maintain proper tail posture.
Conclusion
Our results demonstrated that coordination of opposing sex-specific and core muscle groups, through the activity of multiple neurotransmitters, is required for regulation of male tail posture during mating. We have provided a simple model for regulation of male tail posture that provides a foundation for studies of how genes, molecular pathways, and neural circuits contribute to sensory regulation of this motor behavior
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