104 research outputs found
Photoplethysmographic imaging and analysis of pulsatile pressure wave in palmar artery at 10 wavelengths
CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 International License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.Significance
As a noncontact method, imaging photoplethysmography (iPPG) may provide a powerful tool to measure pulsatile pressure wave (PPW) in superficial arteries and extract biomarkers for monitoring of artery wall stiffness.
Aim
We intend to develop a approach for extraction of the very weak cardiac component from iPPG data by identifying locations of strong PPW signals with optimized illumination wavelength and determining pulse wave velocity (PWV).
Approach
Monochromatic in vivo iPPG datasets have been acquired from left hands to investigate various algorithms for retrieval of PPW signals, distribution maps and waveforms, and their dependence on arterial location and wavelength.
Results
A robust algorithm of pixelated independent component analysis (pICA) has been developed and combined with spatiotemporal filtering to retrieve PPW signals. Spatial distributions of PPW signals have been mapped in 10 wavelength bands from 445 to 940 nm and waveforms were analyzed at multiple locations near the palmar artery tree. At the wavelength of 850 nm selected for timing analysis, we determined PWV values from 12 healthy volunteers in a range of 0.5 to 5.8 m/s across the hand region from wrist to midpalm and fingertip.ECU Open Access Publishing Support Fun
Non-contact and non-invasive water level measurement outside metal pipes with electromagnetic acoustic resonance
Accurate measurements of water levels within metal pipes are vital, particularly in environments where thick-walled pipes serve as critical components, such as in nuclear facilities. Measuring water levels in pipes becomes more difficult under high temperatures and pressures. In response to this need, a method involving electromagnetic acoustic measurement is proposed. This method begins with a transducer emitting a high-frequency pulse designed for precise measurements of wall thickness, then calculates the resonance frequency using the time intervals between echoes. Finally, the transducer emits an excitation signal at the fundamental resonance frequency to measure the water level. At low water levels, the measurement is conducted by manually scanning along the pipes, utilizing varying energy losses. At high water levels, the resonance echo method is employed. Numerical simulations have demonstrated that this approach effectively improves signal amplitude, thereby ensuring the robustness of the measurement. Experimental results also demonstrated that the proposed method boosted the echo signal-to-noise ratio to approximately 15 dB. Additionally, it successfully detected water levels in both aluminum and stainless-steel pipes. Therefore, it is considered to be a highly efficient non-contact and non-invasive method to measure liquid levels in metal pipes, and it has proved to hold significant potential for engineering applications
CPSAA: Accelerating Sparse Attention using Crossbar-based Processing-In-Memory Architecture
The attention mechanism requires huge computational efforts to process
unnecessary calculations, significantly limiting the system's performance.
Researchers propose sparse attention to convert some DDMM operations to SDDMM
and SpMM operations. However, current sparse attention solutions introduce
massive off-chip random memory access. We propose CPSAA, a novel crossbar-based
PIM-featured sparse attention accelerator. First, we present a novel attention
calculation mode. Second, we design a novel PIM-based sparsity pruning
architecture. Finally, we present novel crossbar-based methods. Experimental
results show that CPSAA has an average of 89.6X, 32.2X, 17.8X, 3.39X, and 3.84X
performance improvement and 755.6X, 55.3X, 21.3X, 5.7X, and 4.9X energy-saving
when compare with GPU, FPGA, SANGER, ReBERT, and ReTransformer.Comment: 14 pages, 19 figure
Manipulating Multiple Order Parameters via Oxygen Vacancies: The case of Eu0.5Ba0.5TiO3-{\delta}
Controlling functionalities, such as magnetism or ferroelectricity, by means
of oxygen vacancies (VO) is a key issue for the future development of
transition metal oxides. Progress in this field is currently addressed through
VO variations and their impact on mainly one order parameter. Here we reveal a
new mechanism for tuning both magnetism and ferroelectricity simultaneously by
using VO. Combined experimental and density-functional theory studies of
Eu0.5Ba0.5TiO3-{\delta}, we demonstrate that oxygen vacancies create Ti3+ 3d1
defect states, mediating the ferromagnetic coupling between the localized Eu
4f7 spins, and increase an off-center displacement of Ti ions, enhancing the
ferroelectric Curie temperature. The dual function of Ti sites also promises a
magnetoelectric coupling in the Eu0.5Ba0.5TiO3-{\delta}.Comment: Accepted by Physical Review B, 201
Non-contact and non-invasive water level measurement outside metal pipes with electromagnetic acoustic resonance
Accurate measurements of water levels within metal pipes are vital, particularly in environments where thick-walled pipes serve as critical components, such as in nuclear facilities. Measuring water levels in pipes becomes more difficult under high temperatures and pressures. In response to this need, a method involving electromagnetic acoustic measurement is proposed. This method begins with a transducer emitting a high-frequency pulse designed for precise measurements of wall thickness, then calculates the resonance frequency using the time intervals between echoes. Finally, the transducer emits an excitation signal at the fundamental resonance frequency to measure the water level. At low water levels, the measurement is conducted by manually scanning along the pipes, utilizing varying energy losses. At high water levels, the resonance echo method is employed. Numerical simulations have demonstrated that this approach effectively improves signal amplitude, thereby ensuring the robustness of the measurement. Experimental results also demonstrated that the proposed method boosted the echo signal-to-noise ratio to approximately 15 dB. Additionally, it successfully detected water levels in both aluminum and stainless-steel pipes. Therefore, it is considered to be a highly efficient non-contact and non-invasive method to measure liquid levels in metal pipes, and it has proved to hold significant potential for engineering applications
Gender Difference in 2-Year Mortality and Immunological Response to ART in an HIV-Infected Chinese Population, 2006–2008
Since it was initiated in 2002, the China Free Antiretroviral Treatment (ART) Program has been progressing from an emergency response to a standardized treatment and care system. As of December 31, 2009, a total of 81,880 patients in 31 provinces, autonomous regions, and special municipalities received free ART. Gender differences, however, in mortality and immunological response to ART in this cohort have never been described.To understand whether women and men who enrolled in the China National Free ART Program responded equally well to the treatment.A retrospective analysis of the national free ART databases from June 2006-December 2008 was performed. HIV-infected subjects who were 18 years or older, ART naïve at baseline, and on a 3TC regimen enrolled in the program from June 1 to December 31, 2006, were included in this study, then followed up to 2 years.Among 3457 enrolled subjects who met the inclusion criteria, 59.2% were male and 40.8% female. The majority of the subjects were 19-44 years old (77%) and married (72%). Over the full 24 months of follow-up, the mortality rate was 19.0% in males and 11.4% in females (p = 0.0014). Males on therapy for 3-24 months were more likely to die than females (HR = 1.46, 95% CI: 1.04-2.06, p = 0.0307) after adjusting for baseline characteristics. Compared to men, women had higher CD4+ counts over time after initiating ART (p<0.0001).Our study showed that women had an overall lower mortality and higher CD4+ counts than men in response to ART treatment, which may be attributed to adherence, biological factors, social, cultural and economic reasons. Further study is needed to explore these factors that might contribute to the gender differences in mortality and immunological response to ART
In vivo imaging and modeling of artery blood pressure wave and interaction with light in time domain
Artery blood flow driven by pressure wave is essential for human life. The long-term research goal is to establish a foundation for future translation of the imaging photoplethysmography
(iPPG) method into applications such as extraction of vital health biomarkers. For this dissertation research, we focus on development of a robust framework of hardware and data processing tools for rapid acquisition and analysis of in vivo iPPG data.
Through this project, we have developed a multispectral imaging system for acquisition of time-sequenced iPPG data in vivo from hands of two volunteers with 12 wavelength bands ranging from 445 to 940 nm at a frame rate up to 250 Hz. A fluid dynamic model of blood flow
and pressure wave was employed to quantify the effects of the artery wall deformation with different Young’s modulus, artery radius and other boundary conditions on flow rate and
pressure. A voxel-based Monte Carlo (MC) simulation model has been established for quantitative analysis of the iPPG data based on the radiative transfer theory. The measured
waveforms of iPPG signals at multiple locations in palmar artery have been compared to the waveforms of blood pressure waves calculated with the coupled model of MC and the fluid
dynamic simulations. We have identified the optimal wavelength bands for iPPG illumination to detect palm artery tree and shown that the spatial and temporal distributions of the iPPG signals have strong potentials to monitor heartbeat rate and conditions of artery. The results of this dissertation study provide convincing evidences that iPPG data contain rich information on blood flow and propagation of pressure wave in artery. Consequently, future development of the iPPG method can yield a powerful and non-contact tool to rapidly acquire vital sign data
and quantitatively assess cardiovascular condition
Yield, Nutritional Content, and Antioxidant Activity of Pleurotus ostreatus on Corncobs Supplemented with Herb Residues
Improper disposal of herb residues in China has caused severe problems to the surrounding environment and human safety. Three herb residues, i.e., compound Kushen injection residues (CKI) and part one and part two of Qizhitongluo Capsule residues (QC1 and QC2, respectively), were used for the cultivation of Pleurotus ostreatus. The effect of the supplementation of corncobs (CC) with different herb residues on yield, nutritional composition, and antioxidant activity of P. ostreatus was investigated. Compared to the control, the higher mycelial growth rate was observed on substrates CC +30%Â CKI and CC +30%Â QC1, while the higher yield was obtained from substrates CC +30%Â QC2 and CC +30%Â CKI. Moreover, chemical analysis of fruit bodies revealed that the addition of herb residues to CC significantly increased proteins, amino acids, ashes, minerals (Na and Ca), and total phenolic contents but significantly reduced carbohydrates and IC50 values of DPPH radicals. In addition, no heavy metals (Pb, Cd, and As) were detected in the fruiting bodies harvested from different substrate combinations. These results demonstrated that mixtures of CC with herb residues might be utilized as a novel, practical, and easily available substrate for the cultivation of P. ostreatus, which is beneficial for the effective management of herb residues
Temperature distribution of Collins Ice Cap, King George Island, Antarctica
Temperature measurements in boreholes show that ice is of temperate state in accumulation area and of cold state in ablation area in Collins Ice Cap. Ice temperature of active layer is significantly influenced by seasonal variations of air temperature. The warming of ice by the melt water infiltration is remarkable. Snow cover also noticeably affects thermal regimes of the Collins Ice Cap. The measurements also reveal that temperature below the active layer is approximate to the melting point in the majority of the glacier except in the vicinity of the Little Dome, where ice temperature varies sharply within a surface distance of more than 10 meters. Significant water oozing from the ice cores was observed at a depth of 30m during the drilling near the Little Dome, which is probably caused by the combined effects such as internal runoffs, differential movement and high salinity of the glacier
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