Quantifying the Impact of Climate Change and Human Activities on Streamflow in a Semi-Arid Watershed with the Budyko Equation Incorporating Dynamic Vegetation Information

Understanding hydrological responses to climate change and land use and land cover change (LULCC) is important for water resource planning and management, especially for water-limited areas. The annual streamflow of the Wuding River Watershed (WRW), the largest sediment source of the Yellow River in China, has decreased significantly over the past 50 years at a rate of 5.2 mm/decade. Using the Budyko equation, this study investigated this decrease with the contributions from climate change and LULCC caused by human activities, which have intensified since 1999 due to China’s Grain for Green Project (GFGP). The Budyko parameter that represents watershed characteristics was more reasonably configured and derived to improve the performance of the Budyko equation. Vegetation changes were included in the Budyko equation to further improve its simulations, and these changes showed a significant upward trend due to the GFGP based on satellite data. An improved decomposition method based on the Budyko equation was used to quantitatively separate the impact of climate change from that of LULCC on the streamflow in the WRW. Our results show that climate change generated a dominant effect on the streamflow and decreased it by 72.4% in the WRW. This climatic effect can be further explained with the drying trend of the Palmer Severity Drought Index, which was calculated based only on climate change information for the WRW. In the meantime, although human activities in this watershed have been very intense, especially since 1999, vegetation cover increase contributed a 27.6% decline to the streamflow, which played a secondary role in affecting hydrological processes in the WRW

Assessment of the Effects of Climate Change on Evapotranspiration with an Improved Elasticity Method in a Nonhumid Area

Climatic elasticity is a crucial metric to assess the hydrological influence of climate change. Based on the Budyko equation, this study performed an analytical derivation of the climatic elasticity of evapotranspiration (ET). With this derived elasticity, it is possible to quantitatively separate the impacts of precipitation, air temperature, net radiation, relative humidity, and wind speed on ET in a watershed. This method was applied in the Wuding River Watershed (WRW), located in the center of the Yellow River Watershed of China. The estimated rate of change in ET caused by climatic variables is −10.69 mm/decade, which is close to the rate of change inET (−8.06 mm/decade) derived from observable data. The accurate estimation with the elasticity method demonstrates its reliability. Our analysis shows that ET in the WRW had a significant downward trend, but the ET ratio in the WRW has increased continually over the past 52 years. Decreasing precipitation is the first-order cause for the reduction of ET, and decreasing net radiation is the secondary cause. Weakening wind speed also contributed to this reduction. In contrast, regional warming led to an increase in ET that partly offset the negative contributions from other climatic variables. Moreover, reforestation can affect the energy budget of a watershed by decreasing albedo, compensating for the negative influence of global dimming. The integrated effect from precipitation and temperature can affect the energy budget of a watershed by causing a large fluctuation in winter albedo

Assessment of the Effects of Climate Change on Evapotranspiration with an Improved Elasticity Method in a Nonhumid Area

Climatic elasticity is a crucial metric to assess the hydrological influence of climate change. Based on the Budyko equation, this study performed an analytical derivation of the climatic elasticity of evapotranspiration (ET). With this derived elasticity, it is possible to quantitatively separate the impacts of precipitation, air temperature, net radiation, relative humidity, and wind speed on ET in a watershed. This method was applied in the Wuding River Watershed (WRW), located in the center of the Yellow River Watershed of China. The estimated rate of change in ET caused by climatic variables is −10.69 mm/decade, which is close to the rate of change inET (−8.06 mm/decade) derived from observable data. The accurate estimation with the elasticity method demonstrates its reliability. Our analysis shows that ET in the WRW had a significant downward trend, but the ET ratio in the WRW has increased continually over the past 52 years. Decreasing precipitation is the first-order cause for the reduction of ET, and decreasing net radiation is the secondary cause. Weakening wind speed also contributed to this reduction. In contrast, regional warming led to an increase in ET that partly offset the negative contributions from other climatic variables. Moreover, reforestation can affect the energy budget of a watershed by decreasing albedo, compensating for the negative influence of global dimming. The integrated effect from precipitation and temperature can affect the energy budget of a watershed by causing a large fluctuation in winter albedo

Naturally Occurring Core Protein Mutations Compensate for the Reduced Replication Fitness of a Lamivudine-Resistant HBV Isolate

Hepatitis B virus (HBV) replicates its DNA genome through reverse transcription of an RNA intermediate. The lack of proofreading capacity of the viral DNA polymerase results in a high mutation rate of HBV genome. Under the selective pressure created by the nucleos(t)ide analogue (NA) antiviral drugs, viruses with resistance mutations are selected. However, the replication fitness of NA-resistant mutants is markedly reduced compared to wild-type. Compensatory mutations in HBV polymerase, which restore the viral replication capacity, have been reported to arise under continuous treatment with lamivudine (LMV). We have previously identified a highly replicative LMV-resistant HBV isolate from a chronic hepatitis B patient experiencing acute disease exacerbation. Besides the common YMDD drug-resistant mutations, this isolate possesses multiple additional mutations in polymerase and core regions. The transcomplementation assay demonstrated that the enhanced viral replication is due to the mutations of core protein. Further mutagenesis study revealed that the P5T mutation of core protein plays an important role in the enhanced viral replication through increasing the levels of capsid formation and pregenomic RNA encapsidation. However, the LMV-resistant virus harboring compensatory core mutations remains sensitive to capsid assembly modulators (CpAMs). Taken together, our study suggests that the enhanced HBV nucleocapsid formation resulting from core mutations represents an important viral strategy to surmount the antiviral drug pressure and contribute to viral pathogenesis, and CpAMs hold promise for developing the combinational antiviral therapy for hepatitis B

Embedded Based Miniaturized Universal Electrochemical Sensing Platform

We created an embedded sensing platform based on STM32 embedded system, with integrated carbon-electrode ionic sensor by using a self-made plug. Given ration of concentration-unknown nitrate liquid samples, this platform is able to measure the nitrate concentration in neutral environment. Response signals which were transmitted by the sensor can be displayed via a serial port to the computer screen or via Bluetooth to the smartphone. Processed by a fitting function, signals are transformed into related concentration. Through repeating the experiment many times, the accuracy and repeatability turned out to be excellent. The results can be automatically stored on smartphone via Bluetooth. We created this embedded sensing platform for field water quality measurement. This platform also can be applied for other micro sensors’ signal acquisition and data processing

Inferring subsidence characteristics in Wuhan (China) through multitemporal InSAR and hydrogeological analysis

Wuhan (China) is facing severe consolidation subsidence of soft soil and karst collapse hazards. To quantitatively explore the extent and causes of land subsidence in Wuhan, we performed multitemporal interferometry (MTI) analysis using synthetic aperture radar (SAR) data from the TerraSAR-X satellite from 2013 to 2017 and the Sentinel-1A satellite from 2015 to 2017. MTI results reveal four major subsidence zones in Wuhan, namely, Hankou (exceeding −6 cm/yr), Xudong-Qingshan (−3 cm/yr), Baishazhou-Jiangdi (−3 cm/yr), and Jianshe-Yangluo (−2 cm/yr). Accuracy assessment using 106 levelling benchmarks and cross-validation between the two InSAR-based results indicate an overall root-mean-square error (RMSE) of 2.5 and 3.1 mm/yr, respectively. Geophysical and geological analyses suggest that among the four major subsiding zones, Hankou, Xudong-Qingshan, and Jianshe-Yangluo are located in non-karstic soft soil areas, where shallow groundwater (< 30 m) declines driven by engineering dewatering and industrial water depletion contribute directly to soft soil compaction. Subsidence in the Baishazhou-Jiangdi zone develops in the karst terrain with abundant underground caves and fissures, which are major natural factors for gradual subsidence and karst collapse. Spatial variation analysis of the geological conditions indicates that the stage of karst development plays the most important role in influencing kart subsidence, followed by municipal construction, proximity to major rivers, and overlying soil structure. Moreover, land subsidence in this zone is affected more via coupling effects from multiple factors. Risk zoning analysis integrating subsidence horizontal gradient, InSAR deformation rates, and municipal construction density show that the high-risk areas in Wuhan are mainly distributed in the Tianxingzhou and Baishazhou-Jiangdi zone, and generally spread along the metro lines. © 202

Ultrawideband Frequency-Selective Absorber Designed with an Adjustable and Highly Selective Notch

In this paper, the working mechanism of a wideband absorber designed with an adjustable and highly selective notch band is studied, in which the narrow notch band is independently controlled by the lower lossless layer of the absorber, while the upper lossy layer loaded with lumped resistors realizes absorption. We present two instances with geometrically controlled and electrically controlled notch bands, respectively. Without decreasing absorption performance, the notch position can be flexibly adjusted throughout the entire frequency band by simply modifying the dimension of the lossless frequency-selective surface (FSS) or changing the capacitance of the varactor, i.e., using geometric control or electrical control. The narrow notch band allows two wide absorption bands to be retained on both sides; therefore, good stealth performance is still guaranteed. Equivalent circuit models (ECM) are proposed to further explain the principle. The frequency-domain simulation, ECM, time-domain simulation, and experimental results are in good agreement and validate the adjustability and high selectivity of the notched absorbers. At the end of this paper, an FSA-backed monopole antenna is simulated and measured, which clearly illustrates that these FSAs can serve as the ground plane for antennas and realize out-of-band RCS reduction

End-of-treatment anti-HBs levels and HBeAg status identify durability of HBsAg loss after PEG-IFN discontinuation

BackgroundHepatitis B surface antigen (HBsAg) loss, namely, the functional cure, can be achieved through the pegylated interferon (PEG-IFN)-based therapy. However, it is an unignorable fact that a small proportion of patients who achieved functional cure develop HBsAg reversion (HRV) and the related factors are not well described.MethodsA total of 112 patients who achieved PEG-IFN-induced HBsAg loss were recruited. HBV biomarkers and biochemical parameters were examined dynamically. HBV RNA levels were assessed in the cross-sectional analysis. The primary endpoint was HRV, defined as the reappearance of HBsAg after PEG-IFN discontinuation.ResultsHRV occurred in 17 patients during the follow-up period. Univariable analysis indicated that hepatitis B e antigen (HBeAg) status, different levels of hepatitis B surface antibody (anti-HBs), and hepatitis B core antibody (anti-HBc) at the end of PEG-IFN treatment (EOT) were significantly associated with the incidence of HRV through using the log-rank test. Additionally, time-dependent receiver operating characteristic (ROC) analysis showed that the anti-HBs was superior to anti-HBc in predictive power for the incidence of HRV during the follow-up period. Multivariable Cox proportional hazard analysis found that anti-HBs ≥1.3 log10IU/L (hazard ratio (HR), 0.148; 95% confidence interval (CI), 0.044-0.502) and HBeAg negativity (HR, 0.183; 95% CI, 0.052-0.639) at EOT were independently associated with lower incidence of HRV. Cross-sectional analysis indicated that the HBV RNA levels were significantly correlated with the HBsAg levels in patients with HRV (r=0.86, p=0.003).ConclusionsEOT HBeAg negativity and anti-HBs ≥1.3 log10IU/L identify the low risk of HRV after PEG-IFN discontinuation