Raw ERP with all subjects pooled together.

<p>Green traces correspond to the occipital lateral location displayed with a green circle in the inset while blue correspond to the central occipital location. Solid line correspond to the Control group and the dashed one to the ASD group. The red arrows show an 8ms delay between the minimum of the solid line to the minimum of the dashed one.</p

Time-frequency plots of ICOH for 9 different COI.

<p>Frequencies span only from 0 to 20: Control, right: ASD. Each row corresponds to a different COI, from top to bottom: bilateral (b), frontal-occipital (fo), left (l), right (r), ln (long), o (occipital), occipital temporal (ot), right frontal-parietal (rfp), right parietal-temporal (rpt). See each site description on <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0075941#pone-0075941-t001" target="_blank">table 1</a>.</p

Time-Frequency plots of ICOH values corresponding to control group (top panel), ASD (middle panel) and their difference (bottom panel).

<p>Channels, Tasks and Participants have been pooled together and averaged within each group.</p

ERP averages across groups (Control and ASD) for each scalp site.

<p>Values are interpolated for areas between electrodes. Frequencies and times are the same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0075941#pone-0075941-g003" target="_blank">figure 3</a>.</p

Curves are base-10 logarithms of Pvalues from a number of 3-way ANOVA’s. ANOVA’s were repeated for 181 sliding time windows.

<p>Within each single time window 20 ICOH values were averaged corresponding to a period of 128ms. The 3 factors in the analysis were, the two Groups, Frequencies (considered here as a continuous factor) and COI. Only interaction effects with Groups are shown.</p

. Topographic view of ICOH values. The average of ICOH values of a single channel is mapped to the position of the channel. Values are interpolated for areas between electrodes. Top panel displays the average head of each group for different time points at a fixed frequency (9.8 Hz). Bottom panel the frequency is then varied and the time fixed (196ms).

<p>. Topographic view of ICOH values. The average of ICOH values of a single channel is mapped to the position of the channel. Values are interpolated for areas between electrodes. Top panel displays the average head of each group for different time points at a fixed frequency (9.8 Hz). Bottom panel the frequency is then varied and the time fixed (196ms).</p

Results from a Mann–Whitney <i>U</i> test over 5 putative EEG frequency bands, 48 COI and 20 disjoint time windows of 64 ms each.

<p>There is one panel for each frequency band. Within each panel y-axis denotes time and x-axis COI. White corresponds to regions in which there is a significant difference between both groups where ASD is bigger in ICOH values than Control group. Black denotes significant differences where control is higher. Gray means there are not significant differences. Blue rectangles are shown only to organize the spatial information into 3 distinct anatomical, bilateral, left and right COI. Red rectangles are labeled with red uppercase letters and are used to highlight regions and frequencies that seem to contain a high frequency of significant values.</p

ICOH values are mapped to a line connecting the involved channels, the darker the line the higher the ICOH value.

<p>Frequencies and times are the same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0075941#pone-0075941-g004" target="_blank">figure 4</a>. For clarity, only channels whose ICOH are more than ten standard deviations than the control baseline are shown.</p

Curves are base-10 logarithms of Pvalues, from a number of 3-way ANOVA’s. ANOVA’s were repeated for 181 sliding time windows.

<p>Within each single time window 20 ICOH values were averaged corresponding to a period of 128ms. The 3 factors in the analysis were, the two Groups, Frequencies (considered here as a continuous factor) and Task. The y-axis on the left correspond to factors Task, Group x Task and Frequency x Task. The one on the right is only for Group.</p

Connections of Interest (COI). Connectivity values (ICOH) are averaged into 48 groups of interest.

<p>Connections of Interest (COI). Connectivity values (ICOH) are averaged into 48 groups of interest.</p