8 research outputs found
Power-law scaling of plasma pressure on laser-ablated tin microdroplets
The measurement of the propulsion of metallic microdroplets exposed to nanosecond laser pulses provides an elegant method for probing the ablation pressure in a dense laser-produced plasma. We present the measurements of the propulsion velocity over three decades in the driving Nd:YAG laser pulse energy and observe a near-perfect power law dependence. Simulations performed with the RALEF-2D radiation-hydrodynamic code are shown to be in good agreement with the power law above a specific threshold energy. The simulations highlight the importance of radiative losses which significantly modify the power of the pressure scaling. Having found a good agreement between the experiment and the simulations, we investigate the analytic origins of the obtained power law and conclude that none of the available analytic theories is directly applicable for explaining our power exponent. (C) 2018 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)
Power-law scaling of plasma pressure on laser-ablated tin microdroplets
The measurement of the propulsion of metallic microdroplets exposed to
nanosecond laser pulses provides an elegant method for probing the ablation
pressure in dense laser-produced plasma. We present the measurements of the
propulsion velocity over three decades in the driving Nd:YAG laser pulse
energy, and observe a near-perfect power law dependence. Simulations performed
with the RALEF-2D radiation-hydrodynamic code are shown to be in good agreement
with the power law above a specific threshold energy. The simulations highlight
the importance of radiative losses which significantly modify the power of the
pressure scaling. Having found a good agreement between the experiment and the
simulations, we investigate the analytic origins of the obtained power law and
conclude that none of the available analytic theories is directly applicable
for explaining our power exponent.Comment: 11 pages, 8 figure
Towards a rapid molecular diagnostic for melioidosis: Comparison of DNA extraction methods from clinical specimens
Whole Genome Sequence Typing to Investigate the <em>Apophysomyces</em> Outbreak following a Tornado in Joplin, Missouri, 2011
<div><p>Case reports of <em>Apophysomyces</em> spp. in immunocompetent hosts have been a result of traumatic deep implantation of <em>Apophysomyces</em> spp. spore-contaminated soil or debris. On May 22, 2011 a tornado occurred in Joplin, MO, leaving 13 tornado victims with <em>Apophysomyces trapeziformis</em> infections as a result of lacerations from airborne material. We used whole genome sequence typing (WGST) for high-resolution phylogenetic SNP analysis of 17 outbreak <em>Apophysomyces</em> isolates and five additional temporally and spatially diverse <em>Apophysomyces</em> control isolates (three <em>A. trapeziformis</em> and two <em>A. variabilis</em> isolates). Whole genome SNP phylogenetic analysis revealed three clusters of genotypically related or identical <em>A. trapeziformis</em> isolates and multiple distinct isolates among the Joplin group; this indicated multiple genotypes from a single or multiple sources. Though no linkage between genotype and location of exposure was observed, WGST analysis determined that the Joplin isolates were more closely related to each other than to the control isolates, suggesting local population structure. Additionally, species delineation based on WGST demonstrated the need to reassess currently accepted taxonomic classifications of phylogenetic species within the genus <em>Apophysomyces</em>.</p> </div
List of strains used in study, by isolation site, species and geographic location, along with sequencing coverage results.
<p>NA = Not Applicable; N/A = Not Available; C = Cluster;</p>*<p>indicates multiple isolates from the same patient.</p
WGST phylogeny of outbreak and background Apophysomyces isolates.
<p>A single maximum parsimony tree was reconstructed using ∼28K SNPs from 22 whole genome sequences, resulting in a CI of 0.62. The tree was rooted with Apo-7449 (A. variabilis). The root was derived from an expanded phylogenetic analyses that included a distant outgroup, which enabled the identification of the most basal member of the samples in the dataset described in this figure (data not shown). Genomes are labeled with a Strain ID # (APO-XXXX) and a Cluster ID #-Letter (CX-A). Clusters of identical and nearly identical genome SNP profiles are also labeled. Branch lengths represent genetic distance based on the number of SNP differences; bar represents 1000 SNPs. Tree constructed using MEGA5.</p
<i>De novo</i> assembled reference statistics for Strain Apo-097.
<p><i>De novo</i> assembled reference statistics for Strain Apo-097.</p