Aggressive vertebral hemangioma in early adolescent age group: Atypical presentation with computed tomography and magnetic resonance imaging appearance

Vertebral hemangiomas (VH) are vertebral vascular malformations, which may remain asymptomatic until adulthood. Sometimes,young individuals present with unexplained backache, which poses the diagnostic dilemma. We present a case of 15-year-old femalewho presented with prolonged unexplained intermittent upper back pain in the dorsal region. She was diagnosed as a case of aggressiveVH after ruling out other infective and malignant pathologies and treated with decompressive therapy. The present case highlights therole of imaging studies such as computed tomography and magnetic resonance imaging in such conditions

Importance of Conventional Radiography in Diagnosis and Management of Giant Cell Tumour at an unusual location

Giant cell tumour (GCT) or osteoclastoma of the bone is mostly benign but locally aggressive primary tumour of unknownorigin occurring at epiphysis. It is a tumour of long bones and rarely seen in bones of hand and foot. The cases are reported intarsal and carpal bone but involvement of metatarsal bone is very rare. We present a case of twenty years old female patientwith GCT of second metatarsal of left foot. The patient underwent aggressive curettage and filling with bone chips and is onregular follow up

MRI based volumetric analysis of entorhinal cortex in elderly subjects with mild cognitive impairment and in subjects with normal cognition to see effects of aging on volume of ERC

Background: MCI is a transitional period between normal ageing and clinically probable early Alzheimer’s Dementia (AD). ERC volumes show early reduction in cases of MCI in comparison to the normal ageing subjects. Early cognitive impairment can be documented with ERC atrophy on MR volumetry. Aim of the study was to evaluate the volume of entorhinal cortex in patients of MCI and  to compared the volume with patients of normal cognition. Secondarily, we studied changes in the volume of entorhinal cortex with increasing ageMethods: In this study 30 patients of 60 years and above with MCI and 30 controls of normal cognition (age and sex matched) underwent brain examination on 3T MRI. Volume of entorhinal cortex was measured on 1 mm thick T1 coronal oblique MR scans by manually tracing the boundaries defined by two widely used methods i.e. Insausti et al and Goncharova et al.Results: Patients with MCI showed 17.2% decline in the entorhinal cortex volume compared to controls (p value = 0.001). Patients of older age showed significantly more ERC volume reduction, reaching up to 30.4% in comparison to younger subjects suggesting atrophy of ERC in normal aging and in MCI both, but more so in patients with cognitive impairment.Conclusions: ERC atrophy was found in MCI cases more than controls, increase atrophy trend was noted with increasing age. MR volumetry may play a role for documentation of ERC atrophy in cases of MCI