Data_Sheet_1_Big Five personality and mind wandering in athletes: mediating role of trait anxiety.CSV

ObjectiveMind wandering is a common phenomenon among athletes during training and competition, and can lead to poor performance. We attempt to clarify which personality type is more prone to mind wandering and the role of trait anxiety between them.MethodsSix hundred and eighty-one athletes participated in this cross sectional study. Participants completed the Athlete Mind Wandering Scale, The Chinese adjectives scale of Big-Five factor personality short scale version and Pre-Competition Emotion Scale-Trait questionnaires. The survey data was tested for common method biases, Pearson correlation analysis, and structural equation model by SPSS 25.0 and Mplus 7.0.ResultsCommon method biases can be accepted in this study. (1) Athletes' neuroticism was significantly and positively correlated with trait anxiety and mind wandering, respectively, athletes' extraversion, agreeableness, conscientiousness, and openness were significantly and negatively correlated with trait anxiety and mind wandering respectively; the athletes' trait anxiety was significantly and positively correlated with mind wandering; (2) By constructing mediating models, the direct effects of athletes' extraversion, agreeableness, conscientiousness, neuroticism, and openness on mind wandering were insignificant. The mediating effect of athletes' trait anxiety between the five personalities and mind wandering was significant.ConclusionTrait anxiety in athletes plays a fully mediating role between the relationship of personality and mind wandering. Athletes' extraversion, agreeableness, conscientiousness, neuroticism, and openness can all have an impact on mind wandering through the mediating role of trait anxiety. Athletes can use the mediating role of trait anxiety to intervene the frequency of mind wandering.</p

Modification, characterization and peroxidase-mimetic properties of calcined product of a cobalt compound

<p>One-pot solvothermal treatment of Co(NO₃)₂·6H₂O, H₂<b>L</b> (5-(3-methyl-5-(pyridin-4-yl)-4<i>H</i>-1,2,4-triazol-4-yl) isophthalic acid), and 4,4<i>′</i>-bipyridine (4,4<i>′</i>-bipy) in H₂O/DMF (V/V = 1 : 1) yielded a cobalt-organic chain, [Co(<b>L</b>)(O)(H₂O)₂]_n·1.25nH₂O (<b>1</b>). Compound <b>1</b> as raw materials was calcined to obtain Co₃O₄, which could be confirmed by PXRD and SEM. Via the modification, Co₃O₄@SiO₂-NH₂ and Co₃O₄@SiO₂-NH₂-FA samples could be obtained. Compared to Co₃O₄@SiO₂-NH₂, Co₃O₄@SiO₂-NH₂-FA seems to have better peroxidase-mimetic properties. UV–vis results showed that optimal conditions of peroxidase-mimetic experiments were at 50°C in sodium acetate-acetic acid buffer (pH 3.6, 0.2 M), when the concentration of tetramethylbenzidine (TMB) was 0.2 mM. A concentration-dependent manner was shown between the concentration of glucose and absorbance in the measurement experiments for glucose.</p

Systematic Study in Mammalian Cells Showing No Adverse Response to Tetrahedral DNA Nanostructure

The advent of DNA technology has demonstrated great potential in a wide range of applications, especially in the field of biology and biomedicine. However, current understanding of the toxicological effects and cellular responses of DNA nanostructures remains to be improved. Here, we chose tetrahedral DNA nanostructures (TDNs), a type of nanocarriers for delivering molecular drugs, as a model for systematic live-cell analysis of the biocompatibility of TDNs to normal bronchial epithelial cells, carcinoma cells, and macrophage. We found that the interaction behaviors of TDNs in different cell lines were very different, whereas after internalization, most of the TDNs in diverse cell lines were positioned to lysosomes. By a systematic assessment of cell responses after TDN exposure to various cells, we demonstrate that internalized TDNs have good innate biocompatibility. Interestingly, we found that TDN-bearing cells would not affect the cell cycle progression and accompany cell division and that TDNs were separated equally into two daughter cells. This study improves our understanding of the interaction of DNA nanostructures with living systems and their biocompatibility, which will be helpful for further designing DNA nanostructures for biomedical applications

Systematic Study in Mammalian Cells Showing No Adverse Response to Tetrahedral DNA Nanostructure

The advent of DNA technology has demonstrated great potential in a wide range of applications, especially in the field of biology and biomedicine. However, current understanding of the toxicological effects and cellular responses of DNA nanostructures remains to be improved. Here, we chose tetrahedral DNA nanostructures (TDNs), a type of nanocarriers for delivering molecular drugs, as a model for systematic live-cell analysis of the biocompatibility of TDNs to normal bronchial epithelial cells, carcinoma cells, and macrophage. We found that the interaction behaviors of TDNs in different cell lines were very different, whereas after internalization, most of the TDNs in diverse cell lines were positioned to lysosomes. By a systematic assessment of cell responses after TDN exposure to various cells, we demonstrate that internalized TDNs have good innate biocompatibility. Interestingly, we found that TDN-bearing cells would not affect the cell cycle progression and accompany cell division and that TDNs were separated equally into two daughter cells. This study improves our understanding of the interaction of DNA nanostructures with living systems and their biocompatibility, which will be helpful for further designing DNA nanostructures for biomedical applications

Systematic Study in Mammalian Cells Showing No Adverse Response to Tetrahedral DNA Nanostructure

The advent of DNA technology has demonstrated great potential in a wide range of applications, especially in the field of biology and biomedicine. However, current understanding of the toxicological effects and cellular responses of DNA nanostructures remains to be improved. Here, we chose tetrahedral DNA nanostructures (TDNs), a type of nanocarriers for delivering molecular drugs, as a model for systematic live-cell analysis of the biocompatibility of TDNs to normal bronchial epithelial cells, carcinoma cells, and macrophage. We found that the interaction behaviors of TDNs in different cell lines were very different, whereas after internalization, most of the TDNs in diverse cell lines were positioned to lysosomes. By a systematic assessment of cell responses after TDN exposure to various cells, we demonstrate that internalized TDNs have good innate biocompatibility. Interestingly, we found that TDN-bearing cells would not affect the cell cycle progression and accompany cell division and that TDNs were separated equally into two daughter cells. This study improves our understanding of the interaction of DNA nanostructures with living systems and their biocompatibility, which will be helpful for further designing DNA nanostructures for biomedical applications

Systematic Study in Mammalian Cells Showing No Adverse Response to Tetrahedral DNA Nanostructure

The advent of DNA technology has demonstrated great potential in a wide range of applications, especially in the field of biology and biomedicine. However, current understanding of the toxicological effects and cellular responses of DNA nanostructures remains to be improved. Here, we chose tetrahedral DNA nanostructures (TDNs), a type of nanocarriers for delivering molecular drugs, as a model for systematic live-cell analysis of the biocompatibility of TDNs to normal bronchial epithelial cells, carcinoma cells, and macrophage. We found that the interaction behaviors of TDNs in different cell lines were very different, whereas after internalization, most of the TDNs in diverse cell lines were positioned to lysosomes. By a systematic assessment of cell responses after TDN exposure to various cells, we demonstrate that internalized TDNs have good innate biocompatibility. Interestingly, we found that TDN-bearing cells would not affect the cell cycle progression and accompany cell division and that TDNs were separated equally into two daughter cells. This study improves our understanding of the interaction of DNA nanostructures with living systems and their biocompatibility, which will be helpful for further designing DNA nanostructures for biomedical applications