3 research outputs found
Chiral Selenide-Catalyzed Enantioselective Allylic Reaction and Intermolecular Difunctionalization of Alkenes: Efficient Construction of C‑SCF<sub>3</sub> Stereogenic Molecules
New
approaches for the synthesis of enantiopure trifluoromethylthiolated
molecules by chiral selenide-catalyzed allylic trifluoromethylthiolation
and intermolecular difunctionalization of unactivated alkenes
are disclosed. In these transformations, functional groups were well
tolerated, and the desired products were obtained in good yields with
excellent chemo-, enantio-, and diastereoselectivities. This
reaction is nicely complementary to enantioselective trifluoromethylthiolation,
allylic functionalization, and intermolecular alkene difunctionalization
Chiral Selenide-Catalyzed Enantioselective Allylic Reaction and Intermolecular Difunctionalization of Alkenes: Efficient Construction of C‑SCF<sub>3</sub> Stereogenic Molecules
New
approaches for the synthesis of enantiopure trifluoromethylthiolated
molecules by chiral selenide-catalyzed allylic trifluoromethylthiolation
and intermolecular difunctionalization of unactivated alkenes
are disclosed. In these transformations, functional groups were well
tolerated, and the desired products were obtained in good yields with
excellent chemo-, enantio-, and diastereoselectivities. This
reaction is nicely complementary to enantioselective trifluoromethylthiolation,
allylic functionalization, and intermolecular alkene difunctionalization
Chiral Selenide-Catalyzed Enantioselective Allylic Reaction and Intermolecular Difunctionalization of Alkenes: Efficient Construction of C‑SCF<sub>3</sub> Stereogenic Molecules
New
approaches for the synthesis of enantiopure trifluoromethylthiolated
molecules by chiral selenide-catalyzed allylic trifluoromethylthiolation
and intermolecular difunctionalization of unactivated alkenes
are disclosed. In these transformations, functional groups were well
tolerated, and the desired products were obtained in good yields with
excellent chemo-, enantio-, and diastereoselectivities. This
reaction is nicely complementary to enantioselective trifluoromethylthiolation,
allylic functionalization, and intermolecular alkene difunctionalization