Synthesis of α-Nitro Ketoximes from Styrenes and <i>tert</i>-Butyl Nitrite

<div><p></p><p>We have discovered that various α-nitro ketoximes can be synthesized in good yields starting from styrenes and <i>tert</i>-butyl nitrite. The success of the reaction was critically dependent on the use of a mixture solvent of dimethylsulfoxide and water. The reaction can tolerate a wide variety of substituents including electron-withdrawing and electron-donating groups.</p></div