14 research outputs found
Statistical parametric map showing the significant differences in the ALFF between three groups: depressed PD patients, non-depressed PD patients and NCs.
<p>A) The differences between depressed PD patients and non-depressed PD patients. B) The differences between non-depressed PD patients and NCs. C) The differences between depressed PD patients and NCs. The threshold for display was set to p<0.005, cluster size> = 432 mm<sup>3</sup>.</p
Brain regions exhibiting an altered ALFF between depressed PD patients and non-depressed PD patients.
<p>BA: Brodmann area; MNI: Montreal neurological institute.</p
Brain regions exhibiting an altered ALFF between non-depressed PD patients and NCs.
<p>BA: Brodmann area; MNI: Montreal neurological institute; SMA: supplementary motor area.</p
UiO-66-NH<sub>2</sub>@PMAA: A Hybrid Polymer–MOFs Architecture for Pectinase Immobilization
A hybrid polymer–MOFs architecture
UiO-66-NH<sub>2</sub>@PMAA was synthesized by tethering polymethacrylic
acid (PMAA) onto
the surface of the metal–organic frameworks UiO-66-NH<sub>2</sub>, and it was further employed for pectinase immobilization by electrostatic
interactions. The hybrid architecture was prepared through a combination
of atom transfer radical polymerization (ATRP), click chemistry and
postsynthetic modification (PSM). The optimal immobilization parameters
were at 25 °C and pH 4.0 with 10 U/mL of pectinase for 2 h, under
which pectinase showed the highest enzymatic activity (1.215 U/mg)
and protein loading (448.5 mg/g), respectively. Compared with free
pectinase, the immobilized was found to exhibit higher pH, thermo,
and storage stability. Additionally, the immobilized pectinase had
remarkable reusability, the residual activity reached as high as 81%
after 8 cycles continuously. Meanwhile, the desorption of immobilized
pectinase can be achieved by changing pH values of the medium. Obviously,
the UiO-66-NH<sub>2</sub>@PMAA with attractive properties is highly
promising for enzyme immobilization
Clinical and demographic characteristics.
<p>Note: Abbreviations: HY–Hoehn and Yahr; UPDRS–Unified Parkinson’s Disease Rating Scale; MMSE–Mini Mental state examination.</p
Covalent Organic Network Membranes with Tunable Nanoarchitectonics from Macrocycle Building Blocks for Graded Molecular Sieving
Traditional piperazine-based polyamide
membranes usually suffer
from the intrinsic trade-off relationship between selectivity and
permeance. The development of macrocycle membranes with customized
nanoscale pores is expected to address this challenge. Herein, we
introduce 1,4-diazacyclohexane (2N), 1,4,7-triazacyclononane (3N),
and 1,4,8,11-tetraazacyclotetradecane (4N) as molecular building blocks
to construct the nanoarchitectonics of polyamide membranes prepared
from interfacial polymerization (IP). The permeance of covalent organic
network membranes follows the trend of 4N-TMC > 3N-TMC > 2N-TMC,
while
the molecular weight cutoff (MWCO) also follows the same trend of
4N-TMC > 3N-TMC > 2N-TMC, according to their nanopore size of
the
membranes. The microporosity, orientation, and surface chemistry of
covalent organic network membranes can be rationally designed by macrocycle
building units. The ordered nanoarchitectonics allows the membranes
to attain an excellent performance in graded molecular sieving. Importantly,
the novel covalent organic network membranes with tunable nanoarchitectonics
prepared from macrocycle building units exhibited high water permeance
(32.5 LMH/bar) and retained long-term stability after 100 h of test
and bovine serum albumin fouling. These results reveal the enormous
potential of 3N-TMC and 4N-TMC membranes in saline textile wastewater
treatments and precise molecular sieving
Covalent Organic Network Membranes with Tunable Nanoarchitectonics from Macrocycle Building Blocks for Graded Molecular Sieving
Traditional piperazine-based polyamide
membranes usually suffer
from the intrinsic trade-off relationship between selectivity and
permeance. The development of macrocycle membranes with customized
nanoscale pores is expected to address this challenge. Herein, we
introduce 1,4-diazacyclohexane (2N), 1,4,7-triazacyclononane (3N),
and 1,4,8,11-tetraazacyclotetradecane (4N) as molecular building blocks
to construct the nanoarchitectonics of polyamide membranes prepared
from interfacial polymerization (IP). The permeance of covalent organic
network membranes follows the trend of 4N-TMC > 3N-TMC > 2N-TMC,
while
the molecular weight cutoff (MWCO) also follows the same trend of
4N-TMC > 3N-TMC > 2N-TMC, according to their nanopore size of
the
membranes. The microporosity, orientation, and surface chemistry of
covalent organic network membranes can be rationally designed by macrocycle
building units. The ordered nanoarchitectonics allows the membranes
to attain an excellent performance in graded molecular sieving. Importantly,
the novel covalent organic network membranes with tunable nanoarchitectonics
prepared from macrocycle building units exhibited high water permeance
(32.5 LMH/bar) and retained long-term stability after 100 h of test
and bovine serum albumin fouling. These results reveal the enormous
potential of 3N-TMC and 4N-TMC membranes in saline textile wastewater
treatments and precise molecular sieving
Covalent Organic Network Membranes with Tunable Nanoarchitectonics from Macrocycle Building Blocks for Graded Molecular Sieving
Traditional piperazine-based polyamide
membranes usually suffer
from the intrinsic trade-off relationship between selectivity and
permeance. The development of macrocycle membranes with customized
nanoscale pores is expected to address this challenge. Herein, we
introduce 1,4-diazacyclohexane (2N), 1,4,7-triazacyclononane (3N),
and 1,4,8,11-tetraazacyclotetradecane (4N) as molecular building blocks
to construct the nanoarchitectonics of polyamide membranes prepared
from interfacial polymerization (IP). The permeance of covalent organic
network membranes follows the trend of 4N-TMC > 3N-TMC > 2N-TMC,
while
the molecular weight cutoff (MWCO) also follows the same trend of
4N-TMC > 3N-TMC > 2N-TMC, according to their nanopore size of
the
membranes. The microporosity, orientation, and surface chemistry of
covalent organic network membranes can be rationally designed by macrocycle
building units. The ordered nanoarchitectonics allows the membranes
to attain an excellent performance in graded molecular sieving. Importantly,
the novel covalent organic network membranes with tunable nanoarchitectonics
prepared from macrocycle building units exhibited high water permeance
(32.5 LMH/bar) and retained long-term stability after 100 h of test
and bovine serum albumin fouling. These results reveal the enormous
potential of 3N-TMC and 4N-TMC membranes in saline textile wastewater
treatments and precise molecular sieving
Covalent Organic Network Membranes with Tunable Nanoarchitectonics from Macrocycle Building Blocks for Graded Molecular Sieving
Traditional piperazine-based polyamide
membranes usually suffer
from the intrinsic trade-off relationship between selectivity and
permeance. The development of macrocycle membranes with customized
nanoscale pores is expected to address this challenge. Herein, we
introduce 1,4-diazacyclohexane (2N), 1,4,7-triazacyclononane (3N),
and 1,4,8,11-tetraazacyclotetradecane (4N) as molecular building blocks
to construct the nanoarchitectonics of polyamide membranes prepared
from interfacial polymerization (IP). The permeance of covalent organic
network membranes follows the trend of 4N-TMC > 3N-TMC > 2N-TMC,
while
the molecular weight cutoff (MWCO) also follows the same trend of
4N-TMC > 3N-TMC > 2N-TMC, according to their nanopore size of
the
membranes. The microporosity, orientation, and surface chemistry of
covalent organic network membranes can be rationally designed by macrocycle
building units. The ordered nanoarchitectonics allows the membranes
to attain an excellent performance in graded molecular sieving. Importantly,
the novel covalent organic network membranes with tunable nanoarchitectonics
prepared from macrocycle building units exhibited high water permeance
(32.5 LMH/bar) and retained long-term stability after 100 h of test
and bovine serum albumin fouling. These results reveal the enormous
potential of 3N-TMC and 4N-TMC membranes in saline textile wastewater
treatments and precise molecular sieving
Values of mitochondrial respiratory chain complexes in cultures of normal chondrocytes treated with 20 ng/ml T-2 toxin for 5 days.
<p>Values are the mean ± SD. CS = citrate synthase. †CS-corrected complex activity is expressed as (nmoles/minute/mg protein)/(CS specific activity) ×100. *<i>P</i><0.05 versus normal chondrocytes. #<i>P</i><0.05 versus 20 ng/ml T-2 toxin group. Complex I = rotenone-sensitive NADH-coenzyme Q1 reductase; complex II = succinate dehydrogenase; complex III = antimycin-sensitive ubiquinol cytochrome c reductase; complex IV = cytochrome c oxidase; complex V = ATP synthase.</p><p>Values of mitochondrial respiratory chain complexes in cultures of normal chondrocytes treated with 20 ng/ml T-2 toxin for 5 days.</p