5,827 research outputs found
Opinion dynamics on directed small-world networks
In this paper, we investigate the self-affirmation effect on formation of
public opinion in a directed small-world social network. The system presents a
non-equilibrium phase transition from a consensus state to a disordered state
with coexistence of opinions. The dynamical behaviors are very sensitive to the
density of long-range interactions and the strength of self-affirmation. When
the long-range interactions are sparse and individual generally does not insist
on his/her opinion, the system will display a continuous phase transition, in
the opposite case with high self-affirmation strength and dense long-range
interactions, the system does not display a phase transition. Between those two
extreme cases, the system undergoes a discontinuous phase transition.Comment: 6 pages, 5 figure
Expression of Oct-4 in oncogenic miR-155-positive oral squamous carcinoma cells
Purpose: To identify effective molecular diagnostic methods for oral squamous cell carcinoma (OSCC) to facilitate treatment of the disease in its initial stages.Methods: To identify molecular markers, OSCC tissue samples were collected from cancer patients and healthy controls. CD44+ cells were sorted using quantitative real-time polymerase chain reaction (qRT-PCR). Immunohistochemistry and immunostaining experiments were performed to identify markers for OSCC.Results: The qRT-PCR data confirmed the presence of oncogenic miR-155 in the OSCC samples. The immunohistochemical and immunostaining results confirmed the expression of Oct-4, an important target for the early diagnosis of OSCC, in oncogenic miR-155-positive OSCCs.Conclusion: Detection of the expression of miR-155 and Oct-4, which are key molecular markers, may be useful in improving the early diagnosis of OSCC.Keywords: CD44, oral squamous cell carcinoma, oncogenic miR-155, Oct-
Lurasidone hydroÂchloride
In the crystal structure of the title compound, C28H37N4O2S+·Cl− [systematic name: 4-(1,2-benzothiaÂzol-3-yl)-1-({2-[(3,5-dioxo-4-azaÂtricycloÂ[5.2.1.02,6]decan-4-yl)methÂyl]cycloÂhexÂyl}methÂyl)piperazin-1-ium chloride], the anions and cations are linked by N—H⋯Cl hydrogen bonds. The crystal structure is further stabilized by C—H⋯π and C—H⋯O interÂactions
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