5,827 research outputs found

    Opinion dynamics on directed small-world networks

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    In this paper, we investigate the self-affirmation effect on formation of public opinion in a directed small-world social network. The system presents a non-equilibrium phase transition from a consensus state to a disordered state with coexistence of opinions. The dynamical behaviors are very sensitive to the density of long-range interactions and the strength of self-affirmation. When the long-range interactions are sparse and individual generally does not insist on his/her opinion, the system will display a continuous phase transition, in the opposite case with high self-affirmation strength and dense long-range interactions, the system does not display a phase transition. Between those two extreme cases, the system undergoes a discontinuous phase transition.Comment: 6 pages, 5 figure

    Expression of Oct-4 in oncogenic miR-155-positive oral squamous carcinoma cells

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    Purpose: To identify effective molecular diagnostic methods for oral squamous cell carcinoma (OSCC) to facilitate treatment of the disease in its initial stages.Methods: To identify molecular markers, OSCC tissue samples were collected from cancer patients and healthy controls. CD44+ cells were sorted using quantitative real-time polymerase chain reaction (qRT-PCR). Immunohistochemistry and immunostaining experiments were performed to identify markers for OSCC.Results: The qRT-PCR data confirmed the presence of oncogenic miR-155 in the OSCC samples. The immunohistochemical and immunostaining results confirmed the expression of Oct-4, an important target for the early diagnosis of OSCC, in oncogenic miR-155-positive OSCCs.Conclusion: Detection of the expression of miR-155 and Oct-4, which are key molecular markers, may be useful in improving the early diagnosis of OSCC.Keywords: CD44, oral squamous cell carcinoma, oncogenic miR-155, Oct-

    Lurasidone hydro­chloride

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    In the crystal structure of the title compound, C28H37N4O2S+·Cl− [systematic name: 4-(1,2-benzothia­zol-3-yl)-1-({2-[(3,5-dioxo-4-aza­tricyclo­[5.2.1.02,6]decan-4-yl)meth­yl]cyclo­hex­yl}meth­yl)piperazin-1-ium chloride], the anions and cations are linked by N—H⋯Cl hydrogen bonds. The crystal structure is further stabilized by C—H⋯π and C—H⋯O inter­actions
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