Inbound Marketing

This study looks into inbound marketing practice through the process of secondary research. This insight on best practices and market examples have been employed in order to identify the benefits of Inbound Marketing for the School of Professional Studies at Clark University. Through the research, this team has consolidated a number of recommendations for the SPS marketing strategies moving forward. A focus has been placed on identifying solutions, which were effective and financially feasible. The primary solutions are internally sourced; with a future long term recommendation of seeking advice from a third party firm to automate the process

Evolution and development of Miocene “island dolostones” on Xisha Islands, South China Sea

On Xisha Islands, located in the South China Sea, the Neogene succession includes the unconformity-bounded Huangliu Formation that is 210.5 m thick in well CK-2 and formed almost entirely of dolostones. The diverse biota in the Huangliu Formation, which includes corals, algae, bivalves and foraminifera, indicates that the original carbonate sediments accumulated in water that was < 30 m deep. The dolostones are formed of various mixtures of low- and high-calcium calcian dolomite with limpid dolomite lining the walls of many cavities. The O-18 and C-13 stable isotopes suggest that dolomitization was mediated by slightly modified seawater. The Sr-87/Sr-86 ratios from the dolostones suggest that dolomitization took place similar to 9.4 and 2.3 Ma ago, with the age of dolomitization becoming progressively younger towards the top of the formation. "Island dolostones" like these, found on many islands throughout the Pacific Ocean and the Caribbean Sea, have commonly been linked to eustatic changes in sea-level with dolomitization taking place during lowstands, highstands, or transgressive phases. Data from the Huangliu Formation in well CK-2 suggests that dolomitization was associated with (semi-) continuous transgressive conditions that were controlled by the interaction of tectonic subsidence and eustatic changes in sea level

Coral perspective on temperature seasonality and interannual variability in the northern South China Sea during the Roman Warm Period

Few reconstructions of sea-surface temperature (SST) have focused on seasonal and interannual variability, two major components of the global climate system, due to the limited temporal resolution of proxies. This study presents a combined 228-year-long, monthly resolved strontium to calcium ratios (Sr/Ca) record covering the period of 2070-1740 a BP (years before 1950 CE (Common Era)) extracted from three U-series-based sub-fossil Porites corals located on the Xisha Islands, northern South China Sea (SCS). The composite time series allowed for accurate assessment of the natural range of SST variations during snapshots of the Roman Warm Period (RWP). Reconstructed SST revealed that the RWP was characterized by cooler conditions compared with the 20th century, consistent with climatic variations in the western Pacific and East Asia. The amplitude of SST seasonality was within the modern range, except for a lower value at 1980-1928 a BP. Interannual variability associated with El Nino-Southern Oscillation (ENSO) activity was enhanced by 39% relative to 1980-2014 CE. The results of the sliding window demonstrate that ENSO variability persistently strengthened during 2070-2010 a BP, followed by an overall fluctuating attenuation during 1980-1928 a BP. Then, the trends of rising first before descending twice during 1852-1800 a BP appeared. Furthermore, ENSO activity played a leading role in steering short-term changes in SST seasonality in the northern SCS, manifested as stronger ENSO activity with more frequent El Nino events and decreased SST seasonality. Considering that the frequency of extreme ENSO events may strengthen in the future under global warming, the climate in the northern SCS might become more variable and complex

The Prescription trends and dosing appropriateness analysis of novel oral anticoagulants in ischemic stroke patients: a retrospective study of 9 cities in China

Background: Novel oral anticoagulants (NOACs) have been recommended by guidelines as the first-line drugs for preventing cardiogenic stroke. We aimed to provide an overview of the prescription trends and dosing appropriateness of NOACs in China.Methods: We conducted a retrospective analysis of NOAC prescriptions using the Hospital Prescription Analysis Cooperation Project data from 2016 to 2022. Various patient features, such as gender, age, city, year, source, department visited, original diagnosis, dosing, cost, and insurance type, were collected and analyzed to examine the trends and dosing appropriateness of NOAC usage in ischemic stroke patients.Results: 62,014 NOAC prescriptions were analyzed, including 16,602 for dabigatran, 45,253 for rivaroxaban, and 159 for apixaban. 85.14% of the patients were aged 65 or above, and tertiary hospitals accounted for 95.97% of NOAC prescriptions. NOAC prescriptions rose from 1828 in 2016 to 13,998 in 2021 but dropped to 13,166 in 2022. The percentage of annual prescriptions for NOACs among stroke patients has increased from 0.05% in 2016 to 0.37% in 2022. Total drug cost increased from ¥704541.18 in 2016 to ¥4128648.44 in 2021, then decreased to ¥1680109.14 in 2022. Prescriptions were divided into 48,321 appropriate and 11,262 inappropriate dosing groups, showing significant differences in medications, age, year, city type, hospital level, source, insurance type, and department visited (all p &lt; 0.001). The median drug cost for inappropriate dosing was higher than for appropriate dosing (¥55.20 VS ¥83.80). The top comorbidities in ischemic stroke patients were atrial fibrillation (35.30%), hypertension (32.75%), and coronary heart disease (16.48%).Conclusion: The application of NOACs in the Chinese population is increasing. Our findings highlight the frequent deviation from labeled dosing of NOACs in clinical practice. Continued efforts are necessary to promote the appropriate use of NOACs according to the standard dosage in the drug insert

Supplementary dataset for the research article "Half-meter sea level fluctuations in the western tropical Pacific during the mid-Holocene"

&lt;p&gt;Table 1. U-Th aages of microatolls from Hainan Island, the northern South China Sea&lt;/p&gt

Coral delta O-18-based reconstruction of El Nino-Southern Oscillation from the northern south China sea since 1851 AD

El Nino-Southern Oscillation (ENSO) is the largest source of interannual climate variability over the globe. Knowledge of ENSO variability back to the pre-instrumental period (and earlier) can help to enhance our un-derstanding of its mechanisms and impacts. Here we use the coral record from the northern South China Sea, where the interannual climate variability is associated with ENSO activity, to reconstruct ENSO variability over the past 150 years. Our record, together with other ENSO chronologies, indicated not only the weakened ENSO activity between-1930s and-1960s but also the larger variations of El Nino activity relative to that of La Nina based on the sliding window method. The comparison between the SCS and Pacific ENSO band coral records revealed the relatively stronger climatic coupling between the SCS and the equatorial central-eastern Pacific compared with that between SCS and western Pacific, indicating the reliability of teleconnection relationship between the SCS climate and ENSO. Our result indicated that the coral delta O-18 record from the SCS could con-tribute to the pan-Pacific ENSO reconstructions

YAG:Ce3+ Transparent Ceramic Phosphors Brighten the Next-Generation Laser-Driven Lighting

Y3Al5O12:Ce3+ (YAG:Ce3+) transparent ceramic phosphors (TCPs) are regarded as the most promising luminescent converter for laser-driven (LD) lighting. High-quality YAG:Ce3+ TCPs are still urgent for high efficiency LD lighting devices. YAG:Ce3+ TCPs in a vacuum ambience by using nano-sized raw materials are prepared. Controlling defects by adding nano-sized MgO and SiO2 simultaneously enables a high transmittance nearly 80%. After annealing in air furthermore, the luminous efficiency is enhanced greatly from 106 to 223 lm W-1, which is the best result reported now for LD lighting. These results demonstrate that the optimizing YAG:Ce3+ TCPs in a fitting strategy will brighten once again in the next-generation LD lighting. Based on scanning electron microscopy (SEM) coupled with a cathodoluminescence system, defects and Ce3+ distributions in grains are identified directly for the first time

High‐Resolution Coral Records of Cadmium in Surface Seawater: Biogeochemical Cycling and a Novel Proxy for Winter Monsoon

Abstract Cadmium (Cd) geochemical cycle plays a significant role in the composition and function of the marine ecosystem. Skeletal cadmium‐to‐calcium (Cd/Ca) ratios in hermatypic corals have been applied to reconstruct the historical changes of oceanic and climatic processes, yet there was no systematic evaluation of this tracer's natural variability in high resolution over time. Here, we reported a coral skeletal Cd/Ca record in monthly resolution from 1999 to 2008 CE and reconstructed the history of Cd contents in surface seawater in the northern South China Sea. A significant seasonal variation (higher in the winter but lower in the summer) of Cd contents in surface seawater can be identified. We found that the seasonal variations in coral skeletal Cd/Ca ratios exhibited significant trends coupled with the surface wind speeds, indicating that strong winds had likely driven the vertical seawater mixing process and then induced the process of sediment remobilization on the shelf, which significantly increased Cd contents in surface seawater. The reduction in Cd contents in surface seawater due to biological processes might be masked by the impacts of surface winds. Importantly, we also observed that coral skeletal Cd/Ca records in the winter showed significant correlations with the winter monsoon index, highlighting the possibility as a new proxy of winter monsoon in the non‐upwelling shelf environments

Integrated Infrared Radiation Characteristics of Aircraft Skin and the Exhaust Plume

Infrared radiation (IR) characteristics are important parameters for detecting, identifying, and striking military targets in the context of systematic countermeasures. Accurate calculation of IR characteristics for aircraft is significant for the simulation of war situations and the designation of combat strategy. In this work, integrated IR characteristics of aircraft skin and exhaust plume and their interaction are investigated by considering the reflection based on a bi-directional reflectance distribution function and various influence factors such as solar irradiation, ground reflection, aerodynamic heating, and projection radiation from the background. Combined with infrared emission and reflection characteristics of the skin, omnidirectional IR intensity distributions of 3−5 μm and 8−14 μm at different Mach numbers are obtained. The exhaust plume IR characteristic for different waves and wavebands are also investigated by considering the presence or absence of base and the difference in nozzle inlet temperature. On this basis, integrated IR characteristics between the skin and exhaust plume are investigated. Results show that aircraft IR characteristics of 3−5 μm are concentrated in the exhaust plume and high-temperature skin near the exhaust plume, while the signals of 8−14 μm are concentrated in the skin. The research results are expected to supply guidance for better detection and identification of typical flight targets