202 research outputs found

    High contribution of anthropogenic combustion sources to atmospheric inorganic reactive nitrogen in South China evidenced by isotopes

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    Due to the intense release of reactive nitrogen (Nr) from anthropogenic activity, the source layout of atmospheric nitrogen aerosol has changed. The inorganic nitrogen (NH4+ and NO3-) was essential part of atmospheric nitrogen aerosol and accounted for 69 %. To comprehensively clarify the level, sources, and environmental fate of NH4+ and NO3-, their concentrations and stable isotopes (&delta;15N) in fine particulate matters (PM2.5) were measured in a subtropical megacity of South China. N-NH4+ and N-NO3- contributed 45.8 % and 23.2 % to total nitrogen (TN), respectively. The source contributions of NH4+ and NO3- were estimated by &delta;15N, which suggested that anthropogenic combustion activities including coal combustion, biomass burning, and vehicles were dominant sources. Especially, biomass burning was the predominant source of NH4+ (27.9 %). Whereas, coal combustion was the dominant source of NO3- (40.4 %). This study emphasized the substantial impacts of human activities on inorganic Nr. With the rapid development of industry and transportation, nitrogen emissions will be even higher. The promotion of clean energy and efficient use of biomass would help reduce nitrogen emissions and alleviate air pollution.</p

    Birefringence of GaN/AlGaN optical waveguides

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    This is the published version. Copyright © 2003 American Institute of PhysicsWe have experimentally studied the birefringence of wurtzite GaNgrown on a sapphire substrate. The measurements were done with single-mode GaN/AlGaN planar optical waveguides on c-plane grownheterostructure films. The refractive indices were found to be different for signal optical field perpendicular or parallel to the crystal c axis (n⊥≠n∥). More importantly, we found an approximately 10% change in index difference Δn=n∥−n⊥ with variation of the waveguide orientation in the a–b plane, and a 60° periodicity was clearly observed. This is attributed to the hexagonal structure of nitride materials

    Emission and absorption cross-sections of an Er:GaN waveguide prepared with metal organic chemical vapor deposition

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    This is the published version. ©Copyright 2011 American Institute of PhysicsWe repost the characterization of emission and absorption cross-sections in an erbium-doped GaN waveguide prepared by metal organic chemical vapor deposition. The emission cross-section was obtained with the Füchtbauer–Ladenburg equation based on the measured spontaneous emission and the radiative carrier lifetime. The absorption cross-section was derived from the emission cross-section through their relation provided from the McCumber’s theory. The conversion efficiency from a 1480 nm pump to 1537 nm emission was measured, which reasonably agreed with the calculation based on the emission and absorption cross-sections

    GaN-based waveguide devices for long-wavelength optical communications

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    This is the published version. Copyright © 2003 American Institute of PhysicsRefractive indices of AlxGa1−xN with different Al concentrations have been measured in infrared wavelength regions. Single-mode ridged optical waveguidedevices using GaN/AlGaN heterostructures have been designed, fabricated, and characterized for operation in 1550 nm wavelength window. The feasibility of developing photonic integrated circuits based on III-nitride wide-band-gap semiconductors for fiber-optical communications has been discussed

    A New Fuzzy System Based on Rectangular Pyramid

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    A new fuzzy system is proposed in this paper. The novelty of the proposed system is mainly in the compound of the antecedents, which is based on the proposed rectangular pyramid membership function instead of t-norm. It is proved that the system is capable of approximating any continuous function of two variables to arbitrary degree on a compact domain. Moreover, this paper provides one sufficient condition of approximating function so that the new fuzzy system can approximate any continuous function of two variables with bounded partial derivatives. Finally, simulation examples are given to show how the proposed fuzzy system can be effectively used for function approximation

    Material Properties of GaN in the Context of Electron Devices

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    AbstractWide bandgap nitride semiconductors have recently attracted a great level of attention owing to their direct bandgaps in the visible to ultraviolet regions of the spectrum as emitters and detectors. However, this material system with its favorable heterojunctions and transport properties began to produce very respectable power levels in microwave amplifiers. If and when the breakdown fields achieved experimentally approaches the predicted values, this material system may also be very attractive for switching power devices. In addition to the premature breakdown, a number of scientific challenges remain including a clear experimental investigation of polarization effects. In this paper, transport properties as pertained to electronic devices and potential switching devices, and polarization effects will be treated

    Association between Ghrelin gene (GHRL) polymorphisms and clinical response to atypical antipsychotic drugs in Han Chinese schizophrenia patients

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    <p>Abstract</p> <p>Background</p> <p>Ghrelin (<it>GHRL</it>) is a pivotal peptide regulator of food intake, energy balance, and body mass. Weight gain (WG) is a common side effect of the atypical antipsychotics (AAPs) used to treat schizophrenia (SZ). Ghrelin polymorphisms have been associated with pathogenic variations in plasma lipid concentrations, blood pressure, plasma glucose, and body mass index (BMI). However, it is unclear whether <it>GHRL </it>polymorphisms are associated with WG due to AAPs. Furthermore, there is no evidence of an association between <it>GHRL </it>polymorphisms and SZ or the therapeutic response to AAPs. We explored these potential associations by genotyping <it>GHRL </it>alleles in SZ patients and controls. We also examined the relation between these SNPs and changes in metabolic indices during AAP treatment in SZ subgroups distinguished by high or low therapeutic response.</p> <p>Methods</p> <p>Four SNPs (Leu72Met, -501A/C, -604 G/A, and -1062 G > C) were genotyped in 634 schizophrenia patients and 606 control subjects.</p> <p>Results</p> <p>There were no significant differences in allele frequencies, genotype distributions, or the distributions of two SNP haplotypes between SZ patients and healthy controls (<it>P </it>> 0.05). There was also no significant difference in symptom reduction between genotypes after 8 weeks of AAP treatment as measured by positive and negative symptom scale scores (PANSS). However, the -604 G/A polymorphism was associated with a greater BMI increase in response to AAP administration in both APP responders and non-responders as distinguished by PANSS score reduction (<it>P </it>< 0.001). There were also significant differences in WG when the responder group was further subdivided according to the specific AAP prescribed (<it>P </it>< 0.05).</p> <p>Conclusions</p> <p>These four <it>GHRL </it>gene SNPs were not associated with SZ in this Chinese Han population. The -604 G/A polymorphism was associated with significant BW and BMI increases during AAP treatment. Patients exhibiting higher WG showed greater improvements in positive and negative symptoms than patients exhibiting lower weight gain or weight loss.</p

    III-nitride-based planar lightwave circuits for long wavelength optical communications

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    ©2005 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.Planar lightwave circuits based on III-nitride wide-bandgap semiconductors are proposed and the feasibility of developing III-nitride-based novel photonic integrated circuits for applications in fiber-optical communications is discussed. III-nitrides have low attenuation in the near-infrared wavelength region because of their wide bandgaps, while as semiconductors their refractive indexes can be modulated by carrier injection. III-nitrides are also well known for their ability to operate at high temperatures, high power levels and in harsh environments. These characteristics make III-nitrides ideal candidates for tunable optical phased-array (PHASAR) devices for optical communications. We have characterized the optical properties of AlxGa1-xN epilayers in the 1550-nm wavelength region, including the refractive indexes and the impact of Al concentrations. Single-mode ridged optical waveguide devices using GaN-AlGaN heterostructures have been designed, fabricated and characterized for operation in the 1550-nm wavelength window. The birefringence of wurtzite GaN grown on sapphire substrate has been observed. Refractive indexes were found to be different for signal optical field perpendicular and parallel to the crystal c axis (n(perpendicular to) not equal n(//)). More importantly, we found an approximately 10% change in the index difference Deltan = n(//) - n(perpendicular to) with varying the waveguide orientation within the c plane, and a 60degrees periodicity was clearly observed. This is attributed to the hexagonal structure of the nitride materials. Various functional waveguide devices have been realized, including 2 x 2 directional couplers and eight-wavelength array-waveguide gratings. Theoretical predictions of temperature sensitivity and the efficiency of carrier-induced refractive change are provided

    Common and Specific Functional Activity Features in Schizophrenia, Major Depressive Disorder, and Bipolar Disorder

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    Objectives: Schizophrenia (SZ), major depressive disorder (MDD), and bipolar disorder (BD) are serious mental disorders with distinct diagnostic criteria. They share common clinical and biological features. However, there are still only few studies on the common and specific brain imaging changes associated with the three mental disorders. Therefore, the aim of this study was to identify the common and specific functional activity and connectivity changes in SZ, MDD, and BD.Methods: A total of 271 individuals underwent functional magnetic resonance imaging: SZ (n = 64), MDD (n = 73), BD (n = 41), and healthy controls (n = 93). The symptoms of SZ patients were evaluated by the Positive and Negative Syndrome Scale. The Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI) were used to evaluate the symptoms of MDD patients. The BDI, BAI, and Young Mania Rating Scale were used to evaluate the symptoms of MDD and BD patients. In addition, we compared the fALFF and functional connectivity between the three mental disorders and healthy controls using two sample t-tests.Results: Significantly decreased functional activity was found in the right superior frontal gyrus, middle cingulate gyrus, left middle frontal gyrus, and decreased functional connectivity (FC) of the insula was found in SZ, MDD, and BD. Specific fALFF changes, mainly in the ventral lateral pre-frontal cortex, striatum, and thalamus were found for SZ, in the left motor cortex and parietal lobe for MDD, and the dorsal lateral pre-frontal cortex, orbitofrontal cortex, and posterior cingulate cortex in BD.Conclusion: Our findings of common abnormalities in SZ, MDD, and BD provide evidence that salience network abnormality may play a critical role in the pathogenesis of these three mental disorders. Meanwhile, our findings also indicate that specific alterations in SZ, MDD, and BD provide neuroimaging evidence for the differential diagnosis of the three mental disorders
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