Commanding Wheelchair in Virtual Reality with Thoughts by Multiclass BCI based on Movement-related Cortical Potentials

Brain-driven wheelchair control is an attractive application in theBrain-Computer Interface (BCI) field. In this research, wedesigned and validated a virtual wheelchair navigation systemcontrolled by our latest multiclass BCI Menu interface based on afast brain switch, which provides five commands: move forward,turn left, turn right, move backward, and stop. Preliminary resultshave shown that subjects can successfully control the wheelchairto hit all targets in the immersive virtual reality (VR)environment. This system proves an avenue to bridge the gapbetween simulation control in VR environments and real-lifewheelchair applications for mobility impairment

Targeted drug delivery for the treatment of blood cancers

Blood cancers are a type of liquid tumor which means cancer is present in the body fluid. Multiple myeloma, leukemia, and lymphoma are the three common types of blood cancers. Chemotherapy is the major therapy of blood cancers by systemic administration of anticancer agents into the blood. However, a high incidence of relapse often happens, due to the low efficiency of the anticancer agents that accumulate in the tumor site, and therefore lead to a low survival rate of patients. This indicates an urgent need for a targeted drug delivery system to improve the safety and efficacy of therapeutics for blood cancers. In this review, we describe the current targeting strategies for blood cancers and recently investigated and approved drug delivery system formulations for blood cancers. In addition, we also discuss current challenges in the application of drug delivery systems for treating blood cancers

The research on the performance of linear ultrasonic motor under different temperature

Linear ultrasonic motor (LUSM) is a new type of driver. LUSM has many advantages, so it is taken seriously in aeronautics and astronautics. But, because of the deficiency of studies on the performance of LUSM in abnormal temperature, it’s necessary to do research on the performance of LUSM in different ambient temperature, to confirm whether it can work under abnormal temperature and how it works. In this research, we use V type LUSM (VLUSM) as the test object, owing to that VLUSM is one basic type of linear ultrasonic motor. When doing research, we pay close attention to the moment of force and the rotation rate of VLUSM, to discover how much they change in abnormal temperature environment. This research compares all datum partitioned by different temperature, and uses figures to show the tendency of those mechanical properties in abnormal temperature. At the same time, we explain the changing by means of theories. Finally, through detailed experimental demonstration, we believe that as the temperature rises, both moment of force and rotation rate of VLUSM increase, and we can also conclude that VLUSM can work normally under abnormal temperature environment

Bond formation of surface-tethered receptor-ligand pairs in relative separation

published_or_final_versio

Proper Orthogonal Decomposition in the Generation of Reduced Order Models for Interconnects

In this paper, reduced order models are generated using the technique of proper orthogonal decomposition (POD), also known as Karhunen-Loève decomposition (KLD) for the simulations of interconnect problems. Model order reduction is achieved by projecting the state-space of the original problems onto a subspace spanned by a few numbers of proper orthogonal modes (POMs) extracted by the POD procedure from an ensemble of system responses at a series of selected frequencies. the proper orthogonal values (POVs) corresponding to the POMs indicate the level of the importance of each POM and provide a guidance for the number of POMs to be used in the reduced order models in order to have enough accuracy. Numerical experiment results obtained from the simulations of a two-conductor interconnect and a spiral inductor demonstrate that the reduced order models generated in this way can simulate the original system more effectively and faithfully than those generated with the standard Krylov subspace method with moment matching at a single point. © 2008 IEEE

The Determinants, Inverses, Norm, and Spread of Skew Circulant Type Matrices Involving Any Continuous Lucas Numbers

We consider the skew circulant and skew left circulant matrices with any continuous Lucas numbers. Firstly, we discuss the invertibility of the skew circulant matrices and present the determinant and the inverse matrices by constructing the transformation matrices. Furthermore, the invertibility of the skew left circulant matrices is also discussed. We obtain the determinants and the inverse matrices of the skew left circulant matrices by utilizing the relationship between skew left circulant matrices and skew circulant matrix, respectively. Finally, the four kinds of norms and bounds for the spread of these matrices are given, respectively