101 research outputs found

    Making use of CO2 Capture for Saving Earth and Human - A Comparison of “Carbon Capture and Storage--CCS ”and“ Sarbon Capture and Storage Energy--CCSE”

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    Two technical routes of Carbon Capture and Storage- CCS with Carbon Capture and Storage Energy- CCSE or Smoke Storage Energy-SSE have compared The results show that there are many problems in CCS such as high cost limited application and the application research has not done as yet limited storage zone and safety hazard Therefore author considers that CCS is not a feasible technical route On CCSE or SSE It shows that there are many advantages For example The CO2 considered waste becomes the main raw material for gas production Theoretical calculation shows that energy stored is 3 52 times that of energy consumption unlimlted storage place no safety risks protect the environment conservation of resource

    Phosphorylation of NF-κB in Cancer

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    The proinflammatory transcription factor nuclear factor-κB (NF-κB) has emerged as a central player in inflammatory responses and tumor development since its discovery three decades ago. In general, aberrant NF-κB activity plays a critical role in tumorigenesis and acquired resistance to chemotherapy. This aberrant NF-κB activity frequently involves several post-translational modifications of NF-κB, including phosphorylation. In this chapter, we will specifically cover the phosphorylation sites reported on the p65 subunit of NF-κB and their relationship to cancer. Importantly, phosphorylation is catalyzed by different kinases using adenosine triphosphate (ATP) as the phosphorus donor. These kinases are frequently hyperactive in cancers and thus may serve as potential therapeutic targets to treat different cancers

    Sequential Condition Evolved Interaction Knowledge Graph for Traditional Chinese Medicine Recommendation

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    Traditional Chinese Medicine (TCM) has a rich history of utilizing natural herbs to treat a diversity of illnesses. In practice, TCM diagnosis and treatment are highly personalized and organically holistic, requiring comprehensive consideration of the patient's state and symptoms over time. However, existing TCM recommendation approaches overlook the changes in patient status and only explore potential patterns between symptoms and prescriptions. In this paper, we propose a novel Sequential Condition Evolved Interaction Knowledge Graph (SCEIKG), a framework that treats the model as a sequential prescription-making problem by considering the dynamics of the patient's condition across multiple visits. In addition, we incorporate an interaction knowledge graph to enhance the accuracy of recommendations by considering the interactions between different herbs and the patient's condition. Experimental results on a real-world dataset demonstrate that our approach outperforms existing TCM recommendation methods, achieving state-of-the-art performance

    Impact of epicardial adipose tissue volume on hemodynamically significant coronary artery disease in Chinese patients with known or suspected coronary artery disease

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    BackgroundEpicardial adipose tissue (EAT) is directly related to coronary artery disease (CAD), but little is known about its role in hemodynamically significant CAD. Therefore, our goal is to explore the impact of EAT volume on hemodynamically significant CAD.MethodsPatients who underwent coronary computed tomography angiography (CCTA) and received coronary angiography within 30 days were retrospectively included. Measurements of EAT volume and coronary artery calcium score (CACs) were performed on a semi-automatic software based on CCTA images, while quantitative flow ratio (QFR) was automatically calculated by the AngioPlus system according to coronary angiographic images.ResultsThis study included 277 patients, 112 of whom had hemodynamically significant CAD and showed higher EAT volume. In multivariate analysis, EAT volume was independently and positively correlated with hemodynamically significant CAD [per standard deviation (SD) cm3; odds ratio (OR), 2.78; 95% confidence interval (CI), 1.86–4.15; P < 0.001], but negatively associated with QFRmin (per SD cm3; β coefficient, −0.068; 95% CI, −0.109 to −0.027; P = 0.001) after adjustment for traditional risk factors and CACs. Receiver operating characteristics curve analysis demonstrated a significant improvement in predictive value for hemodynamically significant CAD with the addition of EAT volume to obstructive CAD alone (area under the curve, 0.950 vs. 0.891; P < 0.001).ConclusionIn this study, we found that EAT volume correlated substantially and positively with the existence and severity of hemodynamically significant CAD in Chinese patients with known or suspected CAD, which was independent of traditional risk factors and CACs. In combination with obstructive CAD, EAT volume significantly improved diagnostic performance for hemodynamically significant CAD, suggesting that EAT could be a reliable noninvasive indicator of hemodynamically significant CAD

    Genomic features of bacterial adaptation to plants

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    Author(s): Levy, A; Salas Gonzalez, I; Mittelviefhaus, M; Clingenpeel, S; Herrera Paredes, S; Miao, J; Wang, K; Devescovi, G; Stillman, K; Monteiro, F; Rangel Alvarez, B; Lundberg, DS; Lu, TY; Lebeis, S; Jin, Z; McDonald, M; Klein, AP; Feltcher, ME; Rio, TG; Grant, SR; Doty, SL; Ley, RE; Zhao, B; Venturi, V; Pelletier, DA; Vorholt, JA; Tringe, SG; Woyke, T; Dangl, JL | Abstract: © 2017 The Author(s). Plants intimately associate with diverse bacteria. Plant-associated bacteria have ostensibly evolved genes that enable them to adapt to plant environments. However, the identities of such genes are mostly unknown, and their functions are poorly characterized. We sequenced 484 genomes of bacterial isolates from roots of Brassicaceae, poplar, and maize. We then compared 3,837 bacterial genomes to identify thousands of plant-associated gene clusters. Genomes of plant-associated bacteria encode more carbohydrate metabolism functions and fewer mobile elements than related non-plant-associated genomes do. We experimentally validated candidates from two sets of plant-associated genes: one involved in plant colonization, and the other serving in microbe-microbe competition between plant-associated bacteria. We also identified 64 plant-associated protein domains that potentially mimic plant domains; some are shared with plant-associated fungi and oomycetes. This work expands the genome-based understanding of plant-microbe interactions and provides potential leads for efficient and sustainable agriculture through microbiome engineering

    Progress on Second-Generation High-Temperature Superconductor Tape Targeting Resistive Fault Current Limiter Application

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    The resistive superconducting fault current limiter is well known for its simple structure and outstanding current-limiting effect, and it is broadly applied in power grid systems. The second-generation high-temperature superconductor (HTS) tape, of higher structural strength and greater room-temperature resistance, is well suited for application in resistive superconducting fault current limiters. The quenching caused by overcurrent in the HTS tape is a complexed coupling effect of several physical factors. The tape structure and properties directly impact the ultimate HTS tape’s quench performance. In this study, various SS316-laminated HTS tapes, of different critical currents, room-temperature resistances, and masses, were prepared. The pulse impact parameters of the various tape samples were measured using the RLC high-current impact test platform. By analyzing the resultant data, a quantitative assessment methodology to measure a tape’s tolerance toward impact was developed. The dependence of the HTS tape’s tolerance toward impact on its critical current, room-temperature resistance, and mass was studied. This provides numerical guidance on HTS material selection for resistive superconducting fault current limiters

    A review: Magneto-optical sensor based on magnetostrictive materials and magneto-optical material

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    At present, traditional magnetic field sensors have shortcomings such as large size, complex structure, poor anti-interference ability, and low sensitivity, which are limited in large-scale applications. The magneto-optical sensor has the characteristics of small size, high-integration, stable and reliable in extreme working environment and high sensitivity, which can effectively overcome the above defects and easier to convert it into application products. In this paper, we summarize the magneto-optical sensor based on different used materials, include magnetostrictive materials and magneto-optical materials. We analyzed the sensing mechanisms of these two magneto-optical sensors in detail. The characteristics, structure and performance of magneto-optical sensors are analyzed, the current research progress is summarized, the future development direction of magneto-optical sensors is proposed, and the challenges and development prospects of magneto-optical sensors are analyzed
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