10,367 research outputs found
Research on forming quality of poly-wedge pulley spinning
As an important power transmission part, pulleys are widely used in automobile industry, agricultural machinery, pumps and machines. A near-net forming process for six-wedge belt pulleys manufacturing was put forward. For this purpose, the required tooth shape and size can be formed directly by spinning without machining. The whole manufacturing procedures include blanking, drawing and spinning. The spinning procedure includes five processes, performing, drumming, thickening, toothing and finishing. The forming defects occurred during each forming processes of poly-wedge pulley spinning, such as the drumming failure, flanged opening-end, folded side-wall, insufficient bottom size, flashed opening-end, cutting-off bottom, are introduced, and the factors influencing the defects are analyzed. The corresponding preventive measures are put forward
Macrophage migration inhibitory factor (MIF) family in arthropods : Cloning and expression analysis of two MIF and one D-dopachrome tautomerase (DDT) homologues in Mud crabs, Scylla paramamosain
Acknowledgements This research was supported by grants from the National Natural Science Foundation of China (Nos. 31172438 and U1205123), the Natural Science Foundation of Fujian Province (No. 2012J06008 and 201311180002) and the projects-sponsored by SRF. TW received funding from the MASTS pooling initiative (The Marine Alliance for Science and Technology for Scotland) funded by the Scottish Funding Council (grant reference HR09011) and contributing institutions.Peer reviewedPostprin
Polymorphisms of CYP1A1 I462V and GSTM1 genotypes and lung cancer susceptibility in Mongolian
Aim: To study the genotype of cytochrome P450 1A1(CYP1A1) I462V and glutathions S-transferase M1( GSTM1) and the relationship of the genetic polymorphism of them with the susceptibility of lung cancer in Mongolia of China. 

Methods: Allele-specific PCR and a multiplex PCR were employed to identify the genotypes of I462V of CYP1A1 and GSTM1 in a case-control study of 210 lung cancer patients with bronchoscopy diagnosis and 210 matched controls free of malignancy.

Results: The frequencies of the variant CYP1A1(Val/Val) genotypes and GSTM1(-) in lung cancer groups were higher than that in control groups (15.24% vs 7.4% and 56.67% vs 40.95% ). The individuals who carried with CYP1A1(Val/Val) or GSTM1(-) genotype had a significantly higher risk of lung cancer, the OR is 2.56 and 1.89 respectively. Stratified histologically the relative risk increased to 2.6 - fold when the patients carried with two valine alleles than the ones carried one valine allele in cases of SCC. GSTM1(-) genotype is the risk factor of SCC (OR=2.39) and AC(OR=2.16). The presence of at least one Val allele of CYP1A1 and GSTM1(-), the risk of lung cancer was increased, the OR was 4.15 for one Val allele and GSTM1(-) and 2.67 for two Val alleles and GSTM1 Considering ages and smoking status, the risk of lung cancer increased when the age less than 50 who carried with CYP1A1 valine (one or two) alleles or the age during the 51 to 65 who carried with GSTM1(-) genotype. The light smokers with CYP1A1 valine alleles and GSTM1(-) have a high risk for lung cancer. No association was found between the light and heavy drinkers with the susceptibility of lung cancer and the genetic polymorphisms of CYP1A1 I462V and GSTM1(-). 

Conclusion: The valine allele of CYP1A1 was the risk factors of lung cancer especially for SCC and GSTM1(-) also was the risk factor of lung cancer and especially for SCC and AC of Mongolian, China. Light smoking has a influence each other with genotype of CYP1A1 I462V and GSTM1(-) and susceptibility of lung cancer. No relationship was found between the susceptibility of lung cancer and drinkers with genetic polymorphisms of CYP1A1 I462V and GSTM1(-). The influence of genotypes on the susceptibility of lung cancer may depend on the ages. There may be a synergetic interaction between CYP1A1 valine allele and GSTM1(-) genotypes on the elevated susceptibility of lung cancer. So do those genotypes with light smokers. Key words polymorphism; genotype; lung cancer; cytochrome P450;glutathione S-transferase Abbreviations: SCC, squamous cell carcinoma; AC, adenocarcinoma; SCLC, small cell lung cancer; LCLC, large cell lung cance
Time-Range FDA Beampattern Characteristics
Current literature show that frequency diverse arrays (FDAs) are able of
producing range-angle-dependent and time-variant transmit beampatterns, but the
resulting time and range dependencies and their characteristics are still not
well understood. This paper examines the FDA transmission model and the model
for the FDA array factor, considering their time-range relationship. We develop
two novel FDA transmit beampatterns, both yielding the auto-scanning capability
of the FDA transmit beams. The scan speed, scan volume, and initial mainlobe
direction of the beams are also analyzed. In addition, the equivalent
conditions for the FDA integral transmit beampattern and the multiple-input
multiple-output (MIMO) beampattern are investigated. Various numerical
simulations illustrate the auto-scanning property of the FDA beampattern and
the proposed equivalent relationship with the MIMO beampattern, providing the
basis for an improved understanding and design of the FDA transmit beampattern.Comment: 10 pages, 9 figure
Coherent FDA Receiver and Joint Range-Space-Time Processing
When a target is masked by mainlobe clutter with the same Doppler frequency,
it is difficult for conventional airborne radars to determine whether a target
is present in a given observation using regular space-time adaptive processing
techniques. Different from phased-array and multiple-input multiple-output
(MIMO) arrays, frequency diverse arrays (FDAs) employ frequency offsets across
the array elements, delivering additional range-controllable degrees of
freedom, potentially enabling suppression for this kind of clutter. However,
the reception of coherent FDA systems employing small frequency offsets and
achieving high transmit gain can be further improved. To this end, this work
proposes an coherent airborne FDA radar receiver that explores the
orthogonality of echo signals in the Doppler domain, allowing a joint
space-time processing module to be deployed to separate the aliased returns.
The resulting range-space-time adaptive processing allows for a preferable
detection performance for coherent airborne FDA radars as compared to current
alternative techniques.Comment: 11 pages, 9 figure
Research progress of the diagnosis and treatment for retinal vein occlusion
Retinal vein occlusion( RVO)is a common vascular disease of the retina and is one of the main reasons for blindness. In recent years,there have been some new understanding about the diagnosis and treatment of the disease,especially some new researches about treatment,for example,in the therapy of the intravitreal injection of triamcinolone acetonide and anti-VEGFs as well as dexamethasone implant(Ozurdex).This article will make a brief summarization of the progress about the diagnosis and treatment of RVO
A Model of Two-Way Selection System for Human Behavior
We propose a model of two-way selection system. It appears in the processes
like choosing a mate between men and women, making contracts between job
hunters and recruiters, and trading between buyers and sellers. In this paper,
we propose a model of two-way selection system, and present its analytic
solution for the expectation of successful matching total and the regular
pattern that the matching rate trends toward an inverse proportion to either
the ratio between the two sides or the ratio of the state total to the smaller
people number. The proposed model is verified by empirical data of the
matchmaking fairs. Results indicate that the model well predicts this typical
real-world two- way selection behavior to the bounded error extent, thus it is
helpful for understanding the dynamics mechanism of the real-world two-way
selection system.Comment: 8 pages, 4 figure
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