1′-Acetyl-3-phenyl-6-oxa-4-thia-2-aza­spiro­[bicyclo­[3.2.0]hept-2-ene-7,3′-indolin]-2′-one

In the title indoline compound, C19H14N2O3S, the pyrrolidine ring adopts an envelope conformation with the four-connected (spiro) C atom as the flap [displacement = 0.148 (3) Å]. The mean plane formed through the indoline unit is inclined at dihedral angles of 89.92 (16) and 59.54 (12)° with the thia­zole and phenyl rings, respectively; the dihedral angle between the latter rings is 9.55 (14)°. In the crystal, pairs of inter­molecular C—H⋯O hydrogen bonds link neighbouring mol­ecules into inversion dimers, producing R 2 2(6) hydrogen-bond ring motifs. Weak inter­molecular C—H⋯π as well as π–π inter­actions [centroid–centroid distance = 3.4041 (15) Å] further consolidate the crystal structure

Radiative decays of the heavy-quark-spin molecular partner of Tcc+T_{cc}^+

With the assumptions that the $T_{cc}^+$ discovered at LHCb is a $D^{*}D$ hadronic molecule, using a nonrelativistic effective field theory we calculate the radiative partial widths of $T_{cc}^* \to D^*D\gamma$ with $T_{cc}^*$ being a $D^{*}D^{*}$ shallow bound state and the heavy-quark-spin partner of $T_{cc}^+$. The $I=0$ $D^*D$ rescattering effect with the $T_{cc}$ pole is taken into account. The results show that the isoscalar $D^{\ast} D$ rescattering can increase the tree-level decay width of $T_{cc}^{\ast +}\rightarrow D^{*+}D^0\gamma$ by about $50\%$, while decrease that of $T_{cc}^{\ast +}\rightarrow D^{*0}D^+\gamma$ by a similar amount. The two-body partial decay widths of the $T_{cc}^{*+}$ into $T_{cc}^+\gamma$ and $T_{cc}^+\pi^0$ are also calculated, and the results are about $6~\rm{keV}$ and $3~\rm{keV}$, respectively. Considering that the $D^*$ needs to be reconstructed from the $D\pi$ or $D\gamma$ final state in an experimental measurement, the four-body partial widths of the $T_{cc}^{*+}$ into $DD\gamma\gamma$ and $DD\pi\gamma$ are explicitly calculated, and we find that the interference effect between different intermediate $D^*D\gamma$ states is small. The total radiative decay width of the $T_{cc}^*$ is predicted to be about $24~\rm{keV}$. Adding the hadronic decay widths of $T_{cc}^* \to D^*D\pi$, the total width of the $T_{cc}^*$ is finally predicted to be $(65\pm2)$ keV.Comment: 27 pages, 13 figures. arXiv admin note: text overlap with arXiv:2211.0247

Water-Soluble Flexible Organic Frameworks That Include and Deliver Proteins.

Four water-soluble hydrazone-based three-dimensional (3D) flexible organic frameworks FOF-1-4 have been synthesized from a semirigid tetracationic tetraaldehyde and four flexible dihydrazides. 1H NMR spectroscopy indicated the quantitative formation of FOF-1-4 in D2O, while dynamic light scattering experiments revealed that, depending on the concentration, these porous frameworks display hydrodynamic diameters ranging from 50 to 120 nm. The porosity of the frameworks is confirmed by ethanol vapor adsorption experiments of the solid samples as well as the high loading capacity for a 2.3 nm porphyrin guest in water. The new water-soluble frameworks exhibit low cytotoxicity and form inherent pores with diameters of 5.3 or 6.7 nm, allowing rapid inclusion of proteins such as bovine serum albumin and green and orange fluorescent proteins, and efficient delivery of the proteins into normal and cancer cells. Flow cytometric analysis reveals percentages of the delivered cells up to 99.8%

Electron interaction-driven insulating ground state in Bi2Se3 topological insulators in the two dimensional limit

We report a transport study of ultrathin Bi2Se3 topological insulators with thickness from one quintuple layer to six quintuple layers grown by molecular beam epitaxy. At low temperatures, the film resistance increases logarithmically with decreasing temperature, revealing an insulating ground state. The sharp increase of resistance with magnetic field, however, indicates the existence of weak antilocalization, which should reduce the resistance as temperature decreases. We show that these apparently contradictory behaviors can be understood by considering the electron interaction effect, which plays a crucial role in determining the electronic ground state of topological insulators in the two dimensional limit.Comment: 4 figure