Instability of Dynamic Inventory Systems

We show in this paper that instability is an intrinsic cause of production variability in a dynamic inventory system. We first show that a unique stationary optimal policy exists for both full-backlog and lost-sales case and under the policy a firm replenishes its inventory to a constant target level. We then express the constant inventory target as the unique steady state of the Euler’s equation governing the dynamics of target inventories. We finally show that the Euler’s equation is locally instable at the steady state but a sufficiently large refund to unsold inventory in lost-sales case can stabilize the inventory system.stability, production variability, dynamic inventory system, full-backlog, lost-sales

Delayed hepatic rupture post ultrasound-guided percutaneous liver biopsy: A case report.

RATIONALE: Hemorrhage, one of complications after liver biopsy, is often identified immediately after the procedure while delayed liver rupture is relatively rare. PATIENT CONCERNS: A 45-year-old woman was diagnosed with undetermined liver cirrhosis and abnormal liver function. To determine the etiology and severity of liver cirrhosis, ultrasound-guided liver biopsy was arranged. The patients did not complain any pain during the procedure. Ultrasound examination on postoperative day1 (POD 1) and MRI on POD 3 showed no evidence of hematoma and ascites. On POD 7, however, the patient was taken to the hospital with a sudden onset of pain in the right upper quadrant of the abdomen. DIAGNOSES: Contrast-enhanced computed tomography revealed liver rupture of right inferior segment of the liver with subcapsular hematoma. INTERVENTIONS: Patient was treated with infusion of 2-unit red blood cell suspension, fluid and hemostatics. OUTCOMES: The vital signs of the patient were stabilized after the therapy. The follow-up ultrasound 1 month later showed a shrunken subcapsular hematoma measuring 4.2 × 2.1 cm at the right lobe. LESSONS: Whenever a liver biopsy procedure is performed, the care should be taken to avoid puncturing those areas that may have liver incisure. Moreover, the patient need to rest for several days and to avoid heavy activities, which is one of the major risk factors for post-procedure bleeding

Regional estimation of daily to annual regional evapotranspiration with MODIS data in the Yellow River Delta wetland

Evapotranspiration (ET) from the wetland of the Yellow River Delta (YRD) is one of the important components in the water cycle, which represents the water consumption by the plants and evaporation from the water and the non-vegetated surfaces. Reliable estimates of the total evapotranspiration from the wetland is useful information both for understanding the hydrological process and for water management to protect this natural environment. Due to the heterogeneity of the vegetation types and canopy density and of soil water content over the wetland (specifically over the natural reserve areas), it is difficult to estimate the regional evapotranspiration extrapolating measurements or calculations usually done locally for a specific land cover type. Remote sensing can provide observations of land surface conditions with high spatial and temporal resolution and coverage. In this study, a model based on the Energy Balance method was used to calculate daily evapotranspiration (ET) using instantaneous observations of land surface reflectance and temperature from MODIS when the data were available on clouds-free days. A time series analysis algorithm was then applied to generate a time series of daily ET over a year period by filling the gaps in the observation series due to clouds. A detailed vegetation classification map was used to help identifying areas of various wetland vegetation types in the YRD wetland. Such information was also used to improve the parameterizations in the energy balance model to improve the accuracy of ET estimates. This study showed that spatial variation of ET was significant over the same vegetation class at a given time and over different vegetation types in different seasons in the YRD wetlan

Diagnostic Accuracy of CEUS LI-RADS for the Characterization of Liver Nodules 20 mm or Smaller in Patients at Risk for Hepatocellular Carcinoma.

Background: American College of Radiology contrast agent–enhanced US Liver Imaging Reporting and Data System (CEUS LI-RADS) was developed to improve the accuracy of hepatocellular carcinoma (HCC) diagnosis at contrast agent2enhanced US. However, to the knowledge of the authors, the diagnostic accuracy of the system in characterization of liver nodules 20 mm or smaller has not been fully evaluated. Purpose: To evaluate the diagnostic accuracy of CEUS LI-RADS in diagnosing HCC in liver nodules 20 mm or smaller in patients at risk for HCC. Materials and Methods: Between January 2015 and February 2018, consecutive patients at risk for HCC presenting with untreated liver nodules 20 mm or less were enrolled in this retrospective double-reader study. Each nodule was categorized according to the CEUS LI-RADS and World Federation for Ultrasound in Medicine and Biology (WFUMB)–European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) criteria. Diagnostic performance of CEUS LI-RADS and WFUMB-EFSUMB characterization was evaluated by using tissue histologic analysis, multiphase contrast-enhanced CT and MRI, and imaging follow-up as reference standard and compared by using McNemar test. Results: The study included 175 nodules (mean diameter, 16.1 mm 6 3.4) in 172 patients (mean age, 51.8 years 6 10.6; 136 men). The sensitivity of CEUS LR-5 versus WFUMB-EFSUMB criteria in diagnosing HCC was 73.3% (95% confidence inter-val [CI]: 63.8%, 81.5%) versus 88.6% (95% CI: 80.9%, 94%), respectively (P, .001). The specificity of CEUS LR-5 versus WFUMB-EFSUMB criteria was 97.1% (95% CI: 90.1%, 99.7%) versus 87.1% (95% CI: 77%, 94%), respectively (P = .02). No malignant lesions were found in CEUS LR-1 and LR-2 categories. Only two nodules (of 41; 5%, both HCC) were malignant in CEUS LR-3 category. The incidences of HCC in CEUS LR-4, LR-5, and LR-M were 48% (11 of 23), 98% (77 of 79), and 75% (15 of 20), respectively. Two of 175 (1.1%) histologic analysis2confirmed intrahepatic cholangiocarcinomas were categorized as CEUS LR-M by CEUS LI-RADS and misdiagnosed as HCC by WFUMB-EFSUMB criteria. Conclusion: The contrast-enhanced US Liver Imaging Reporting and Data System (CEUS LI-RADS) algorithm was an effective tool for characterization of small (≤20 mm) liver nodules in patients at risk for hepatocellular carcinoma (HCC). Compared with World Federation for Ultrasound in Medicine and Biology2European Federation of Societies for Ultrasound in Medicine and Biology criteria, CEUS LR-5 demonstrated higher specificity for diagnosing small HCCs with lower sensitivity

Time–Frequency Cepstral Features and Heteroscedastic Linear Discriminant Analysis for Language Recognition

The shifted delta cepstrum (SDC) is a widely used feature extraction for language recognition (LRE). With a high context width due to incorporation of multiple frames, SDC outperforms traditional delta and acceleration feature vectors. However, it also introduces correlation into the concatenated feature vector, which increases redundancy and may degrade the performance of backend classifiers. In this paper, we first propose a time-frequency cepstral (TFC) feature vector, which is obtained by performing a temporal discrete cosine transform (DCT) on the cepstrum matrix and selecting the transformed elements in a zigzag scan order. Beyond this, we increase discriminability through a heteroscedastic linear discriminant analysis (HLDA) on the full cepstrum matrix. By utilizing block diagonal matrix constraints, the large HLDA problem is then reduced to several smaller HLDA problems, creating a block diagonal HLDA (BDHLDA) algorithm which has much lower computational complexity. The BDHLDA method is finally extended to the GMM domain, using the simpler TFC features during re-estimation to provide significantly improved computation speed. Experiments on NIST 2003 and 2007 LRE evaluation corpora show that TFC is more effective than SDC, and that the GMM-based BDHLDA results in lower equal error rate (EER) and minimum average cost (Cavg) than either TFC or SDC approaches