Study on Traffic Status Threshold Based on Floating Taxi

AbstractThe applications of floating car in road traffic condition identification are taken seriously and gradually developed. The paper studies the variables threshold in traffic condition information based on the floating taxi: section traffic information update cycle, data sampling interval, section covering ratio, floating taxi sample size. The optimization idea of floating taxi sample size is given. The traffic condition identification algorithm based on the floating taxi is put forward. The practice in two road sections shows that the algorithm is feasible which can offer useful reference for urban traffic management and resident trips decision

FOXE1 polyalanine tract length screening by MLPA in idiopathic premature ovarian failure

<p>Abstract</p> <p>Background</p> <p>FOXE1 is one of the candidate genes for genetic predisposition to premature ovarian failure (POF) and it contains an alanine tract. Our purpose is to assess the influence of length of the alanine tract of FOXE1 on genetic susceptibility to POF.</p> <p>Methods</p> <p>The group studied consisted of 110 Chinese patients with idiopathic POF and 110 women from normal controls. The polyalanine tract and flanking sequence of FOXE1 was screened using the Multiple Ligation-dependent Probe Amplification (MLPA) technique and directly sequenced.</p> <p>Results</p> <p>Three variants of FOXE1-polyalanine length, containing 12, 14, or 16 alanine residues, and 5 different genotypes were identified. There were significantly lower frequencies of the 14/14 genotypes in cases with POF (X2 = 119.73, P = 0.001), as compared with the controls. The incidence of 16/16 genotypes of FOXE1-polyalanine was significantly higher in patients with POF (X2 = 3.403, P = 0.001) in comparison to the controls. The FOXE1 14 alanine allele was significantly less common in the POF patient group (186/220) than the controls (216/220) (X2 = 25.923, P = 0.0001). The FOXE1 16 alanine allele was significantly more common in the POF patient group (28/220) than the controls (4/220) (X2 = 19.412, P = 0.0001).</p> <p>Conclusion</p> <p>This finding provides evidence that polyalanine repeat expansions in FOXE1 may be responsible for the genetic aetiology of POF in Chinese women.</p

Exercise Intervention Associated with Cognitive Improvement in Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disease with the syndrome of cognitive and functional decline. Pharmacotherapy has always been in a dominant position for the treatment of AD. However, in most cases, drug therapy is accompanied with clinical delays when older adults have suffered from cognitive decline in episodic memory, working memory, and executive function. On the other hand, accumulating evidence suggests that exercise intervention may ameliorate the progression of cognitive impairment in aging ones while the standard strategy is lacking based on different levels of cognitive decline especially in mild cognitive impairment (MCI) and AD. MCI is the preclinical stage of AD in which neurodegeneration may be reversed via neuroplasticity. Therefore, taking exercise intervention in the early stage of MCI and healthy aging at the risk of AD could slow down the process of cognitive impairment and provide a promising cost-effective nonpharmacological therapy to dementia

Possible Origin of the Damocloids:the Scattered Disk or a New Region?

The Damocloids are a group of unusual asteroids, recently enrolling a new member of 2010 EJ104. The dynamical evolution for the Damocloids may uncover a connection passage from the Main Belt, the Kuiper Belt and the scattered disk beyond. According to our simulations, two regions may be considered as possible origin of the Damocloids: the scattered disk, or a part of Oort cloud which will be perturbed to a transient region locating between 700 AU and 1000 AU. Based on the potential origin, the Damocloids can be classified into two types, with relation to their semi-major axes, and about 65.5% Damocloids is classified into type I which mainly originate from Oort cloud. Whether the Damocloids is inactive nuclei of Halley Family Comets may rely on their origin.Comment: 10 pages, 5 figures, accepted for publication in Research in Astronomy and Astrophysic

Absolute instability modes due to rescattering of stimulated Raman scattering in a large nonuniform plasma

Absolute instability modes due to rescattering of SRS in a large nonuniform plasma is studied theoretically and numerically. The backscattered light of convective SRS can be considered as a pump light with a finite bandwidth. The different frequency components of the backscattered light can be coupled to develop absolute stimulated Raman scattering (SRS) and two plasmon decay (TPD) instability near their quarter-critical densities via rescattering process. The absolute SRS mode develops a Langmuir wave with a high phase velocity about c/ √3 with c the light speed in vacuum. Given that most electrons are at low velocities in the linear stage, the absolute SRS mode grows with much weak Landau damping. When the interaction evolves into the nonlinear regime, the Langmuir wave can heat abundant electrons up to a few hundred keV. Our theoretical model is validated by particle-in-cell simulations. The absolute instabilities may play a considerable role for the indirect-drive experiments of inertial confined fusion

Changes in activities of both photosystems and the regulatory effect of cyclic electron flow in field-grown cotton (Gossypium hirsutum L) under water deficit

To clarify the influence of water deficit on the functionality of the photosynthetic apparatus of cotton plants, leaf gas exchange, chlorophyll a fluorescence, and P700 redox state were examined in field-grown cotton Gossypium hirsutum L. cv. Xinluzao 45. In addition, we measured changes in the P515 signal and analyzed the activity of ATP synthase and the trans-thylakoid proton gradient (ΔpH). With increasing water deficit, the net CO2 assimilation rate (AN) and stomatal conductance (gs) significantly decreased, but the maximum quantum efficiency of PSII photochemistry (Fv/Fm) did not change. The photochemical activity of photosystem II (PSII) was reflected by the photochemical quenching coefficient (qP), quantum efficiency of photosystem II [Y(II)], and electron transport rate through PSII [ETR(II)], while the activity of photosystem I (PSI) was reflected by the quantum efficiency of photosystem I [Y(I)] and the electron transport rate through PSI [ETR(I)]. Both activities were maintained under mild water deficit, but were slightly decreased under moderate water deficit. Under moderate water deficit, cyclic electron flow (CEF), the fraction of absorbed light dissipated thermally via the ΔpH- and xanthophyll-regulated process [Y(NPQ)], and the fraction of P700 oxidized under a given set of conditions [Y(ND)] increased. Our results suggest that the activities of both photosystems are stable under mild water deficit and decrease only slightly under moderate water deficit. Moderate water deficit stimulates CEF, and the stimulation of CEF is essential for protecting PSI and PSII against photoinhibition.This study was financially supported by the National Natural Science Foundation of China (U1203283; 31260295) and by the Training Program for Outstanding Young College Teachers (Grant No. CZ027201)

Correction: Hong, K. et al. Actinomycetes for Marine Drug Discovery Isolated from Mangrove Soils and Plants in China. Mar. Drugs 2009, 7, 24–44

We found an error in our paper published in Marine Drugs [1]. [...

Effect of acute exposure of Hg on physiological parameters and transcriptome expression in silkworms (Bombyx mori)

Mercury (Hg) contamination poses a global threat to the environment, given its elevated ecotoxicity. Herein, we employed the lepidopteran model insect, silkworm (Bombyx mori), to systematically investigate the toxic effects of Hg-stress across its growth and development, histomorphology, antioxidant enzyme activities, and transcriptome responses. High doses of Hg exposure induced evident poisoning symptoms, markedly impeding the growth of silkworm larvae and escalating mortality in a dose-dependent manner. Under Hg exposure, the histomorphology of both the midgut and fat body exhibited impairments. Carboxylesterase (CarE) activity was increased in both midgut and fat body tissues responding to Hg treatment. Conversely, glutathione S-transferase (GST) levels increased in the fat body but decreased in the midgut. The transcriptomic analysis revealed that the response induced by Hg stress involved multiple metabolism processes. Significantly differently expressed genes (DEGs) exhibited strong associations with oxidative phosphorylation, nutrient metabolisms, insect hormone biosynthesis, lysosome, ribosome biogenesis in eukaryotes, and ribosome pathways in the midgut or the fat body. The findings implied that exposure to Hg might induce the oxidative stress response, attempting to compensate for impaired metabolism. Concurrently, disruptions in nutrient metabolism and insect hormone activity might hinder growth and development, leading to immune dysfunction in silkworms. These insights significantly advance our theoretical understanding of the potential mechanisms underlying Hg toxicity in invertebrate organisms