Recent advances in the diagnosis of Kawasaki disease

Kawasaki disease (KD) has been increasing recently in Korea. Although the delayed diagnosis of KD can cause coronary artery abnormalities, no specific test is available. Thus, optimal guidelines for early diagnosis and treatment of KD are the best way to prevent the development of coronary artery abnormalities. The 2017 updated American Heart Association guidelines for diagnosis, treatment, and long-term management of KD are informative for physicians who face with children having manifestations suggestive of KD

HD-DEMUCS: General Speech Restoration with Heterogeneous Decoders

This paper introduces an end-to-end neural speech restoration model, HD-DEMUCS, demonstrating efficacy across multiple distortion environments. Unlike conventional approaches that employ cascading frameworks to remove undesirable noise first and then restore missing signal components, our model performs these tasks in parallel using two heterogeneous decoder networks. Based on the U-Net style encoder-decoder framework, we attach an additional decoder so that each decoder network performs noise suppression or restoration separately. We carefully design each decoder architecture to operate appropriately depending on its objectives. Additionally, we improve performance by leveraging a learnable weighting factor, aggregating the two decoder output waveforms. Experimental results with objective metrics across various environments clearly demonstrate the effectiveness of our approach over a single decoder or multi-stage systems for general speech restoration task.Comment: Accepted by INTERSPEECH 202

Evaluation of Classification Possibility of Coke Breeze by Drag Force

Sintered ore used as blast furnace burden materials is produced by mixing iron ore, coke, and limestone, then burning the coke and sintering the iron ore with the combustion heat. Among the coke charged, A particle size of 0.25 mm or less has an insignificant effect as a heat source and adhere to the surface of other materials to inhibit the reaction between oxygen and raw materials, thereby decreasing the quality of sintered ore. Therefore, to increase combustion efficiency, it is necessary to reduce the ratio of coke breeze in the charged coke. In this study, theoretical calculation, experiment and simulation were conducted to investigate the possibility of size classification by drag force in the process of dropping coke after being transported through a belt conveyor. The height of belt conveyor was at 1m, and velocity of the belt was 1.5, 2.3, and 2.6 m/s, which were considered as experimental variables. After falling, the distribution of coke particle size according to the horizontal travel distance was confirmed, and a fall trajectory prediction formula model was created through the drag model of polydisperse system and compared with the experimental and analysis results

A Distributed Inference System for Detecting Task-wise Single Trial Event-Related Potential in Stream of Satellite Images

Brain-computer interface (BCI) has garnered the significant attention for their potential in various applications, with event-related potential (ERP) performing a considerable role in BCI systems. This paper introduces a novel Distributed Inference System tailored for detecting task-wise single-trial ERPs in a stream of satellite images. Unlike traditional methodologies that employ a single model for target detection, our system utilizes multiple models, each optimized for specific tasks, ensuring enhanced performance across varying image transition times and target onset times. Our experiments, conducted on four participants, employed two paradigms: the Normal paradigm and an AI paradigm with bounding boxes. Results indicate that our proposed system outperforms the conventional methods in both paradigms, achieving the highest $F_{\beta}$ scores. Furthermore, including bounding boxes in the AI paradigm significantly improved target recognition. This study underscores the potential of our Distributed Inference System in advancing the field of ERP detection in satellite image streams

Effect of Hydraulic Activity on Crystallization of Precipitated Calcium Carbonate (PCC) for Eco-Friendly Paper

Wt% of aragonite, a CaCO3 polymorph, increased with higher hydraulic activity (°C) of limestone in precipitated calcium carbonate (PCC) from the lime-soda process (Ca(OH)2-NaOH-Na2CO3). Only calcite, the most stable polymorph, was crystallized at hydraulic activity under 10 °C, whereas aragonite also started to crystallize over 10 °C. The crystallization of PCC is more dependent on the hydraulic activity of limestone than CaO content, a factor commonly used to classify limestone ores according to quality. The results could be effectively applied to the determination of polymorphs in synthetic PCC for eco-friendly paper manufacture

Epstein-Barr Virus Antibodies in Kawasaki Disease

The prevalent ages at onset for Kawasaki Disease (KD) and Epstein-Barr virus (EBV) infection are known to be similar in Korea and Japan. We evaluated the correlation between EBV infection and KD. The antibodies to EBV such as anti-viral capsid antigen (VCA) IgG and IgM, anti-diffuse and restricted early antigen IgG (anti-EADR IgG), and the anti-EBV determined nuclear antigen IgG (anti-EBNA IgG) were examined in 29 KD patients at five separate times sequentially during a period of one year, and also in 14 other children with a past history of KD. The results of each group were compared with those of age-matched controls. The positive rates of anti-VCA IgG and IgM at presentation in the KD patients were 41.4% (12/29) and 0% (0/29), respectively. Only one patient was found to be anti-VCA IgM-positive within two months. There were no cases of anti-VCA IgG except one, anti-EADR IgG and anti-EBNA IgG positive to negative seroconversion during the year. The children with a past history of KD showed higher anti-EBNA IgG-positive rates than the controls (p = 0.04). There was no difference in the seropositive rates of the antibodies to EBV, cytomegalovirus, herpes simplex virus and herpes zoster virus. In conclusion, children with KD were noted to have normal immune responses to EBV infection. Children with a past history of KD seemed to be infected with EBV at a later age than children with no history of KD

A Presumed Etiology of Kawasaki Disease Based on Epidemiological Comparison With Infectious or Immune-Mediated Diseases

Background: Kawasaki disease (KD) may be associated with infection of unknown pathogen(s). For predicting of the etiology of KD, we evaluated epidemiological characteristics in KD, common infectious diseases and immune-mediated diseases in childhood.Methods: We respectively, reviewed the data of patients with KD, influenza, aseptic meningitis, exanthem subitum (ES), Mycoplasma pneumoniae (MP) pneumonia, acute pyelonephritis (APN), Henoch-Schönlein purpura (HSP), acute poststreptococcal glomerulonephritis (APSGN), and childhood asthma. We compared and interpreted epidemiological data across the groups.Results: In age distribution, KD, APN, and ES showed a similar pattern in that majority of patients were infants or young children, and other diseases showed a relatively even age-distribution which had a peak age, mainly 5–6 years, with bell-shape patterns. In annual-case pattern, there were epidemic years in aseptic meningitis and MP pneumonia, and the fluctuated annual cases were seen in other diseases. The trends of decreasing cases were seen in APSGN, HSP, and childhood asthma in recent years. In seasonal frequency, influenza or aseptic meningitis occurred in mainly winter or summer season, respectively. HSP and APSGN cases had less in summer, and KD, APN, and ES showed relatively even occurrence throughout a year without significant seasonal variations.Conclusions: Our results suggest that KD agents may be associated with normal flora that are influenced by environmental changes, since pathogens of APN and ES could be regarded as normal flora that originate from the host itself or ubiquitously existing human reservoirs