RESTful web service to build loosely coupled web based simulation of human physiology

Abstract-This work introduces a concept based on RESTful web service bringing a new layer into the architecture of web based simulation for the domain of modeling and simulation of physiological systems. The result is growing set of models and simulation application controllable by less powerful client devices but allowing long term simulation or identification of physiological system on remote servers or high performance computing centers. II. SIMULATION We propose an architecture with independent RESTful web service that is loosely coupled with simulation on the server and visualization on the client. Byrne et al. III. CONCLUSION Only lightweight integration via HTTP and JSON data format is needed when changing or introducing new type of visualization technology. The client application was introduced in HTML (version 5) with Javascript and in environment for mathematical computing (MathWork's MATLAB, Wolfram's Mathematica). The same lightweight integration is needed on the simulation side for different types of simulation. In the case of identification of physiological systems, high performance computing may boost it when high number of simulation must be computed. The simulation packages can be deployed within national scientific computing centers or European Grid Iniciative (EGI

Integrované modely fyziologických systémů

Ústav patologické fyziologieInstitute of Pathological Physiology1. lékařská fakultaFirst Faculty of Medicin