149 research outputs found
Non-biased investigation of standardized <em>Ginkgo biloba</em> preparations by <sup>1</sup>H NMR-based metabolomics and HPLC-PDA-MS-SPE-NMR
HPLC-SPE-NMR hyphenation in natural products research: optimization of analysis of <em>Croton membranaceus</em> extract
Multivariate analysis of integrated and full-resolution <sup>1</sup>H-NMR spectral data from complex pharmaceutical preparations: St. John's wort
The effects of conformational constraints in the polyamine moiety of philanthotoxins on AMPAR inhibition
Structural analysis of complex saponins of <em>Balanites aegyptiaca</em> by 800 MHz <sup>1</sup>H NMR spectroscopy
Application of rotated PCA models to facilitate interpretation of metabolite profiles:commercial preparations of St. John's wort
Terpenoids of <em>Salvia hydrangea</em>: two new, rearranged 20-norabietanes and the effect of oleanolic acid on erythrocyte membrane
The antiparasitic compound Licochalcon A is a potent echinocytogenic agent that modifies erythrocyte membrane in the concentration region where the antiplasmodial activity is observed
The well-known antiparasitic compound licochalcone A is a potent membrane-active agent that transforms normal erythrocytes into echinocytes in parallel with the inhibition of growth of Plasmodium falciparum cultures, the in vitro antiplasmodial effect apparently being an indirect effect on the host cell. In vitro experiments with synchronous cultures demonstrate that inhibition of invasion is the principal mechanism of growth inhibition. The erythrocyte membrane-modifying effect was also transiently observed in vivo in mice after intravenous administration
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